Cov tshuaj "Merkazolil" qhia

Cov tshuaj los nyob rau hauv cov ntsiav tshuaj daim ntawv. Pharmacological txiav txim raws li
antithyroid thaj chaw ntawm lub active tshuaj - methimazole (5 mg nyob rau hauv 1 ntsiav tshuaj). Tshuaj "Merkazolil", xyuas cov kws kho mob paub meej tias nws cheeb qhov uas cov enzyme peroxidase, uas yog tsis yooj yim sua yam uas tsis tau cov tshuaj tiv thaiv iodization ntawm lub qog hormones nyob rau hauv lub qog caj pas. Cov no ib tug disturbance ntawm lub tsim kho mob thyroxine thiab triiodothyronine.

Methimazole yog zoo yaim los ntawm lub hnyuv ib ntsuj av. Lub ib nrab-lub neej yog 6 teev. Nws yog metabolized nyob rau hauv lub cev, nws yog kiag li tshem tawm los ntawm ob lub raum.

Cov tshuaj "Merkazolil" qhia

Cov tshuaj no yog tshuaj:

• ntawm tireotoksicheskom Stroke ;
• nyob rau hauv diffuse lom goiter;
• nyob rau hauv mixed lom goiter nyob rau hauv lub complex kev kho mob nrog thyroid hormonal kab mob los yog tej iodine txoj kev kho.

Tshuaj "Merkazolil": cov lus qhia rau kev siv

Ntau npaum tus kws kho mob xaiv ib lub zuj zus nyob rau hauv tus neeg mob tus mob. Feem ntau cov tshuaj 20 mg rau 40 mg ntawm methimazole txhua txhua hnub. Pom zoo txhua hnub koob tshuaj muab faib mus rau hauv 2-4 koob tshuaj. Normalization ntawm lub qog muaj nuj nqi cai tom qab kev kho mob merkazolilom ntev ntawm 3-ex rau 8 lub lis piam. Tom qab qhov zoo tshwm sim tau tus neeg mob yog pauv mus rau ib tug txij nkawm Thiamazolum kho nyob rau hauv koob tshuaj xws li los ntawm 2.5 mg rau 10 mg ib hnub twg.

Therapeutic hnub koob tshuaj rau cov me nyuam ntawm los ntawm 1 mus rau 300 micrograms per kg 500 mg rau ib 1 kg. Supportive hnub koob tshuaj rau cov me nyuam yog los ntawm 1 mus rau 200 micrograms per kg mus rau 300 mg rau ib 1 kg. Tu koob tshuaj methimazole muab ib-lub sij hawm, nyob rau hauv thaum sawv ntxov tom qab noj tshais.

Txhais tau hais tias "Merkazolil": phiv

Thaum lub sij hawm soj ntsuam ntawm cov tshuaj muaj cai tsis tshua kev tsis haum tshuaj nyob rau hauv daim ntawv ntawm ib tug ua pob liab vog los yog kub taub hau; nyob rau hauv ib tug neeg cov neeg mob qhia cov tsos mob volchanochnopodobnogo syndrome.

Kev ua txhaum ntawm lub hematopoietic system tsis tshua muaj leukopenia, agranulocytosis; tsos mob ntawm generalized lymphadenopathy muaj cai nyob rau hauv ib cov neeg mob.

Irregularities nyob rau hauv lub digestive system tsis tshua muaj kev hloov nyob rau hauv saj; nyob rau hauv ib tug neeg cov neeg mob nws twb ntes tau koj lub siab mob, yuav txhawb kom mus ntuav thiab xeev siab.

Teeb nyob rau hauv lub paj hlwb yog los nrog nkawd tham xwb nyob rau hauv ib tug ob peb tus neeg mob, tshwm sim neuritis thiab polyneuritis, mob taub hau.

Disruptions rau lub endocrine system tsom hyperplasia ntawm lub qog caj pas.

Cov tshuaj "Merkazolil" qhia: contraindications

Nws yog tsis yooj yim sua rau muab ib tug yeeb tshuaj:

• nyob rau hauv kev mob loj leukopenia los yog granulocytopenia;
• npau taws me ntsis rau methimazole;
• thaum lub sij hawm cev xeeb tub;
• lactation.

Tshwm sim los ntawm cov tshuaj "Merkazolil" cev xeeb tub cov poj niam uas muaj feem xyuam rau nws muaj peev xwm yuav hla tus placental barrier. Yog li ntawd, txoj kev siv cov methimazole tom qab kuv peb lub hlis fraught nrog txoj kev loj hlob ntawm hypothyroidism nyob rau hauv lub fetus.

Tshwm sim los ntawm cov tshuaj "Merkazolil" mis-pub niam yog vim nws muaj peev xwm mus txeem mus rau hauv niam cov kua mis.

Tshuaj "Merkazolil" Kev qhia: tshwj xeeb cov lus qhia

Thiamazolum kev kho mob yuav yuav tsum tau mus tsis tu ncua saib xyuas cov ntshav duab.

Kev kho mob ntawm loj strum Thyroid nyuab constriction ntawm lub raj cua yuav tsum tau muab luv luv. Heev kev kho mob yuav ua rau txoj kev loj hlob ntawm lub Struma.

Nco ntsoov nqa tawm ib tug sab laj rau tus neeg mob ua ntej kev kho mob merkazolilom mus piav qhia txog qhov yuav tsum tau mus ntsib ib tug kws kho mob thaum thawj cov cim qhia ntawm tsis zoo hloov nyob rau hauv lub xeev. Qhov no ua npaws, mob caj pas, mob ntawm lub qog ua kua week ntawm lub qhov ncauj, qhov tsos ntawm lub rwj - raug cov tsos mob ntawm agranulocytosis.

Thaum lub yavtom ntej phais lub sij hawm Merkazolil tso tseg 1-2 lub lis piam. Kev npaj rau strumectomy nqa iodine-muaj tshuaj.

Nws yog ib qho tseem ceeb los ua tim nyob rau hauv lub siab hais tias tsis muaj ntawm iodine nyob rau hauv lub cev ntawm tus neeg mob tsub kom cov nyhuv ntawm methimazole, thiab iodine tshaj txo cov nyhuv ntawm methimazole.