"Hydrea": phau ntawv qhia, xyuas, cov duab, analogues

Tshuaj "Hydrea" belongs rau anticancer tshuaj. Cov tshuaj muaj ib tug cytostatic nyhuv, lub mechanism ntawm uas yog raws li nyob rau hauv lub inhibition ntawm DNA synthesis, nrog cov teebmeem nyob ntawm RNA thiab protein synthesis yog uas ploj lawm.

Nyob rau hauv dab tsi daim ntawv nws yog manufactured yeeb tshuaj, yog dab tsi nws muaj?

Lub medicament yog tawm nyob rau hauv daim ntawv ntawm cov tshuaj ua raws li hydroxycarbamide, uas yog 500 mg rau hauv txhua capsule. Cov tshuaj no muaj nyob rau hauv lub khob vial (100 tsiav tshuaj), los yog ib tug sawv hlwv pob (10 tsiav tshuaj). Ntawm koom haum pab Cheebtsam siv magnesium stearate thiab citric acid. Tsis tas li ntawd, cov muaj pes tsawg leeg yog supplemented nrog sodium phosphate hydrogen dihydrate thiab lactose monohydrate.

Cov tshuaj uas tshwm sim tawm lub plhaub ntawm tsiav tshuaj "Hydrea" cov lus qhia yog titanium dioxide, dyes thiab gelatin. Lub inscription yog tsim los ntawm ib tug number case uas yog tau vim muaj ib tug compound ntawm propylene glycol, shellac, haus cawv (isopropyl, methylated muaj thiab N-butyl), thiab lim dej thiab hlau oxide dub.

pharmacodynamics

Cov tshuaj no yog ib qho antimetabolite, nws cov nyhuv yog manifested nyob rau hauv lub cell voj voog S theem. "Hydrea" tso cai rau kom tsis txhob loj hlob ntawm lub hlwb nyob rau hauv interphase G1-S, uas yog tseem ceeb heev rau ib txhij nrog lub txais tos ntawm cov medicament nqa radiotherapy, raws li nyob rau hauv G1 theem mob hlwb yog nkag mus irradiation. Cov kev npaj tej qhov kev txiav txim sib sib zog tsa ribonukleoziddifosfatreduktazoy (RNA reductase inhibitor). Los ntawm txoj kev siv inhibited DNA synthesis, tab sis tsis cuam tshuam protein thiab RNA tsim.

tshuaj

Haum ntawm cov tshuaj nyob rau hauv lub mob huam "Hydrea" phau ntawv qhia no qhia txog yuav ua li cas ceev tsis tau los ntawm khoom noj khoom haus kom tsawg thiab ua rau kev kawm tau ntawm cov qib siab tshaj plaws ntawm active tshuaj nyob rau hauv lub cev txog ob teev tom qab noj nqos tau cov ib tug nrog txhais tau tias. Lub medicament kis tau los ntawm cov ntshav-hlwb barrier, yus muaj los ntawm ib tug sai faib tam sim no nyob rau hauv ascites thiab hlwb txha nqaj qaum kua. Cov tshuaj no yog tsim nyob rau hauv erythrocytes thiab leukocytes cov tas tsis pub dhau peb mus rau plaub lub sij hawm. Ib nrab metabolism hauv lub siab. Feem ntau ntawm cov tshuaj no yog tas los ntawm ob lub raum nyob rau hauv daim ntawv ntawm cov hydroxyurea, ib tug yam ntxwv ntev ntawm tus txheej txheem no yog kaum ob teev. Nws tsis hloov ib co ntawm nws cov tsos, ib tug me me npaum li cas yog muab tshem tawm los ntawm lub cev nyob rau hauv cov zis. Ntawm qhov ua pa ib ntsuj av tau tshuaj tas li carbon dioxide. Tom qab tau txais "Hydrea" qhia tshaj tawm nws tiav tshem tawm nyob rau hauv ib hnub twg. Txij li thaum lub feem tseem ceeb ntawm cov tshuaj kis tau los ntawm ob lub raum, nyob rau hauv cov neeg mob uas muaj ib tug pathology hauv nruab nrog cev, txo lub koob tshuaj ntawm cov tshuaj.

zaj lus tim khawv

"Hydrea" qhia ntawv nyob rau daim ntawv thov tso cai rau koj mus muab nyob rau hauv xws tej yam kev mob ntawm tus kab mob:

• melanoma;
• myelogenous leukemia;
• cancer, txoj kev loj hlob ntawm cov uas muaj feem xyuam rau lub ncauj tsev menyuam, mob ntsws, prostate, nyuv los yog zes qe menyuam (txoj kev kho yuav tsum tau ua ke);
• osteomyelofibrosis;
• erythremia;
• lub xub ntiag ntawm ib tug phem qhov xwm ntawm hlav nyob rau hauv lub caj dab thiab taub hau, tsuas kos yog ib tug mob cancer uas muaj feem xyuam rau ob daim di ncauj (muaj ib tug xav rau ib tug kev kho mob);
• Qhov tseem ceeb thrombocythemia;
• horionepitelioma tsev menyuam;
• mob lymphoblastic leukemia txaus;
• thrombocytosis raws li ib tug mob myeloproliferative syndrome;
• Hodgkin tus kab mob;
• tshwm sim ntawm metastasis nyob rau hauv cancer, cov ua mammary caj pas thiab lub plab.

Contraindications

Muaj mob nyob rau hauv uas cov kev kho mob yog tsis tsim nyog txhais tau tias "Hydrea". Tshuaj qhia txwv tsis pub tsa nyob rau hauv xws li mob:

• High rhiab heev rau lub tsiav tshuaj;
• thrombocytopenia thiab leukopenia ntawm cov nqi uas tsawg tshaj li 100,000 thiab 2500 / ml feem;
• cev xeeb tub, mis-pub mis.

Txawm tias nyob rau hauv cov nram no tus neeg mob thiab cov tshuaj tsis yog txhob, thaum nws tau raug tsa thiab daim ntawv thov yuav tsum tau kev pab tshwj xeeb:

• glucose-galactose malabsorption;
• lactose intolerance;
• tsis muaj lactase;
• Heavy ntws anemia;
• tsis ua hauj lwm lub raum thiab lub siab.

Yog hais tias tus neeg mob tau yav tas los raug rau cov kws khomob los yog tawg txoj kev kho, txoj kev pheej hmoo ntawm mob tawg erythema thiab kev loj hlob ntawm myelosuppression, yog li ntawd, nyob rau hauv cov ntaub ntawv no, dhau lawm, yuav tsum maj mam muab thov rau cov tshuaj.

Thaum lub sij hawm txoj kev kho xav tau txhim khu kev qha pov, yog tias cuaj kaum lub cev xeeb tub, tus neeg mob yuav tsum tau paub txog cov kev pheej hmoo tias tshwm sim rau lub fetus. Vim lub allergic ntawm cov tshuaj mus rau hauv cov mis mis nyuj ntawm cov poj niam uas pub niam mis, nws yog tsim nyog mus lawm no hom ntawm noj. Yog hais tias cov tshuaj yog npaj mus rho, ib tug kws yuav tsum coj mus rau hauv tus account lub ntau yam ntsiab lus ua ntej nws yuav tso cai rau tus neeg mob tsis kam kho raws li nyob rau hauv lub txais tos ntawm tsiav tshuaj "Hydrea".

kev kho mob

Thaum lub sij hawm kev kho mob lub medicament "Hydrea" phau ntawv qhia xav siv ntau koob tshuaj neeg sawv cev nyob rau hauv sib txawv xeev, muab cov yam ntxwv ntawm tus neeg mob.

Yog hais tias tus neeg mob yog ib qhov nyuaj rau nqos lub tshuaj ntsiav, nws yog siv tau rau cov qhib ntawm lub tshuaj yaj nyob rau hauv dej. Nyob rau hauv xws li mob, tus neeg saib xyuas yuav tsum tau haus tam sim ntawd. Nws yuav tsum tau borne nyob rau hauv lub siab hais tias tsis yog tag nrho cov Cheebtsam ntawm lub tsiav tshuaj yaj nyob rau hauv dej, ntxiv rau nws saum npoo. Cov neeg mob uas raug kho "Hydrea", nws yog tsim nyog los haus dej kom ntau.

Myelogenous leukemia (mob daim ntawv no)

Kev kho mob yog ua tsis tau cuam tshuam. Rau txhua kilogram ntawm lub cev hnyav noj 20-30 mg ntawm cov tshuaj. Qhov no txhua txhua hnub tus nqi, cov tshuaj yog noj ib zaug txhua txhua hnub. Opportunity rau kev ntsuam xyuas cov hauj lwm zoo ntawm txoj kev kho tau lawm tam sim no rau 1.5 lub hlis ntawm nws siv. Yog hais tias zoo tau yog muab sau, cov kev kho mob yuav ua tau ntev txaus (nyob rau hauv kev xav tau thereof), nyob ntog theem ntawm platelets thiab leukocytes hauv qab no nws cai nres. Yog hais tias tom qab peb hnub (tsis tau ua ntej) cov ntshav rov qab mus rau li qub, koj yuav tau rov pib dua txoj kev kho nrog "Hydrea". Cov lus qhia rau kev siv qhia tau hais tias hais tias xws li ib lub sij hawm los sai sai.

erythremia

Cov kev kawm tshuaj rau lub hnub koom haum saib xyuas ntawm 15-20 mg. Raws li nyob rau hauv lub yav dhau los cov ntaub ntawv, qhov no npaum li cas cov tshuaj yog xam rau ib kilogram ntawm lub cev hnyav. Lub hnub tus neeg mob yog feem ntau muab 1 los yog 2 tsiav tshuaj. Kawg koob tshuaj rau txhua tus neeg mob yog txiav txim los ntawm nws qhov hnyav, nws nyob ntawm tus nqi ntawm cov tshuaj uas platelets thiab hematocrit ntau ntau li qub qhov tseem ceeb.

Qhov tseem ceeb thrombocythemia

Cov thawj zaug koob tshuaj rau ib kilogram ntawm lub cev hnyav coj mus rau 15 mg. Lub sij hawm tshuaj tom ib lub zuj zus li ntawd ib qho tseem ceeb yam nyob rau hauv txoj cai theem. Yog hais tias txwv tsis pub txoj kev siv tshuaj "Hydrea" qhia lus tus kws kho mob tshuaj xyuas thiab xaiv lub feem ntau tsim nyog txhais tau tias.

melanoma

Nrog loj hlav kev kho mob yuav tsum yog sib quas ntus los yog mus li, ntsig txog, rau qhov tsim nyog koob tshuaj medicament ib muaj ib tug kilogram ntawm qhov ceeb thawj yog 80 mg los sis 20-30. Thaum peb lub lis piam, qhov ntev ntawm tas mus li txoj kev kho tshuaj txhua txhua hnub haus ib zaug. Yog hais tias txoj kev kho yog nqa tawm intermittently rau peb hnub, haus dej haus ib yam nkaus thiab ib zaug, tab sis nyob rau ib tug ntau dua koob tshuaj.

Carcinoma (lub tsev me nyuam lesion, lub taub hau los yog lub caj dab)

Ib kilogram lub cev hnyav lawm 80 mg ntawm yeeb tshuaj. Cov kev kawm koob tshuaj yog noj txhua txhua peb hnub (ib zaug).

phiv

Thaum tshuaj kho "Hydrea" kev qhia ntawv, kev txheeb xyuas tau qhia ib co kev phiv rau lub hematopoietic system, lub paj hlwb, urinary, ua pa thiab digestive systems. Tsis tas li ntawd, daim tawv nqaij yuav muaj cuam tshuam thiab lawv appendages yog tau los tsim xws li ib tus kab mob, raws li gangrene. Yuav cim thiab lwm yam kev phiv tshuaj.

Tus nqi ntawm cov tshuaj, analogues

Yuav pob "Hydrea" yuav ua tau rau 243-250 rubles. (20 tsiav tshuaj). Ntawm cov hloov - preparations uas muaj qhov tib active ingredient ua tus "Hydrea" thiab cov tshuaj uas muaj ib tug zoo li cov nyhuv.

Ntawm txhais koj mus yuav "hydroxyurea" los yog "Hydroxycarbamide Medak." Thaum txwv tsis pub kho mob "Hydrea" phau ntawv no, analogs yuav tau xaiv los ntawm ib tug loj tus naj npawb ntawm medicaments, xws li "Tromboreduktina" "amyl FS", "Kolotekana", "Milanfor", "Prospidin", "iritis", "halava", "Estratsita" "Irinotela", "Kamptotekana" los yog "Estratsita". Koj muaj peev xwm yuav hloov xws li "Agrilin", "Kamptera" los yog "Erivedzh". Ntawm cov chaw muaj xws li cov kev nqis tes ua "Aranoza", "Irinaks", "Arglabin". Daim ntawv teev cov uas zoo sib xws tshuaj roos "Zaltrap", "Irnokam", "Geksalen". Nws muaj peev xwm yuav kho tau "Proksifeinom", "Gikamtinom", "Campto", "Verotekanom", "Hloditanom", "prospidin", "Onkofagom", "irinotecan" los yog "Velcade".

Xyuas

Muaj ntau cov neeg mob ntseeg tau hais tias ua ntej pib txoj kev kho yuav tsum tau tshawb hauj lwm txhais tau tias "Hydrea" kev qhia ntawv. Duab ua ntej thiab koj yuav tau saib cov post-kev kho mob. Judging los ntawm cov kev txheeb xyuas, cov neeg xav yuav tsum tau kho xwb nyob rau hauv kev kho mob saib xyuas thiab yuav raug tsis rau nws tus kheej-medicate, raws li qhov no yog txaus ntshai, haus dej kom ntau. Yog hais tias tsis noj tshuaj ua ke nrog tawg txoj kev kho, kev phiv los yog tshwm sim (nyob rau hauv tus neeg mob qhov twg yav tas los tsis tuaj kawm ntawv), los yog ua ntau txawm tias pronounced. Tab sis nws tsis yeej ib txwm tshwm sim.