Levonorgestrel: yog dab tsi no lawm, thiab rau cov uas nws yog lub luag hauj lwm nyob rau hauv lub cev?

Muaj coob tus neeg xav: levonorgestrel - yog dab tsi no lawm? Qhov no yog ib tug hluavtaws progestagen uas converts endometrium minimizes ovulation inhibiting fertilization oocyte npaj. Tsis tas li ntawd, nws muaj peev xwm mucosal receptors tsis rhiab heev yog tau. Nyob rau hauv no tsab xov xwm peb yuav saib kev npaj muaj ib yam tshuaj hu ua.

pharmacology

Cov tshuaj "Levonorgestrel" - yog cov tshuaj no, uas tiv thaiv qhov ua kom cov phev vim kom hnoos qeev viscosity zog. Cov tshuaj ua zos nyob rau hauv lub tsev me nyuam nyob rau hauv txoj hlab qe raj, lub endometrium, lub taub hau ntawm lub hnoos qeev, ua follicle-stimulating lawm thiaj li txoj kev.

Haus hu ua tshuaj nquag yaim nyob rau hauv lub mob huam, Bioindication txog li 100%. Nyob rau hauv cov ntshav, nws cov Cheebtsam yog feeb meej nyob rau hauv lub siab tshaj plaws kev txais tos razovo 75 ml tom qab 60 - 130 feeb. Saib hormone ua num ua ke nrog ntshav thiab globulin losis tswvyim dabtsi yog kwv yees li 50%.

Metabolism hauv yog teem rau hauv lub siab, lub passive daim ntawv pharmacologically metaboliks. Lub ntsiab isoenzyme ntawm no lawm yog CYP3A4. Lub ib nrab-lub neej lub sij hawm tej zaum yuav kav mus txog 30 teev.

zog

Nyob rau hauv cov lus teb rau cov nqe lus nug "Levonorgestrel - dab tsi yog no lawm?" yuav tsum tau ua los ntawm cov kev qhia ntawv ntawm lub tib lub npe tshuaj thiab lub tswv yim pom zoo ntawm cov mus kawm tus kws kho mob. Indicators feem ntau txawv tus nqi ntawm qhov kev txiav txim ntawm 1.0 ml / min. / Kg (cov ntshav). Cov tshuaj yog tshem tawm mas los ntawm lub ureter, ib feem me me yog muab tshem tawm los ntawm cov quav.

Nyob rau hauv cov kev kho mob ntawm muaj quag xwm ntog ceev ntsuas nyob rau hauv lub tsev me nyuam yog tsis ntau tshaj 20 mg txhua hnub, thiab tom qab tsib xyoo lub caij nplooj zeeg mus rau 11 Qhov nruab nrab tso zis nqi ntawm cov hormone txawv nyob ib ncig ntawm 14 ug / 24 hr. Nyob 50-60 lub hlis.

Intrauterine txoj kev kho tso cai rau cov poj niam nrog ib tug hloov lawm kev kho mob nyob rau hauv nrog cov tshuaj no, progestin yog tsis xws li muaj pes tsawg leeg. Levonorgestrel - ib yam tshuaj kev cog hniav nyob rau hauv ntshav 60 feeb tom qab thawj coj. Maximum concentration therein yog kaw tom qab 14 hnub ntawm daim ntawv thov.

zaj lus tim khawv

Kev siv cov tshuaj no yog tau nrog intrauterine txoj kev kho, raws li tau zoo raws li nyob rau hauv cov nram no mob:

• Idiopathic menorrhagia orientation.
• Long-term contraceptive tiv thaiv.
• Kev tiv thaiv rau hloov yuav txo tau nrog cov tshuaj no.
• Thaum muaj xwm ceev thaum muaj xwm ceev pov.

Cov tshuaj levonorgestrel, cov nyhuv uas muaj ib tug broad tau, cov nram qab no yuav tsum thov tsuas yog tom qab kev pom zoo ntawm ib tug kws kho mob.

Siv thiab ntau npaum

Xam tias yog ib tug yeeb tshuaj tshuab txais los ntawm intrauterine txhaj - txhaj mus rau hauv lub uterine kab noj hniav. Siv rau 4 hnub tom qab com nyob rau hauv tus nqi ntawm cov 0.75 rau 1.5 mg. Thaum muaj xwm ceev pov cov kws txawj xav qhia tsis tau xyaum ntau tshaj li ib zaug txhua rau lub hlis.

Yuav kom tshem tawm lub cev ntas, nws yog tsim nyog los ua raws li cov pom zoo npaum tsis rov siv. Tsis txhob siv qhia tshuaj hais raws li ib tug txoj kev ntawm mus tas li pov, raws li qhov no provokes cov tsos mob tshwm sim thiab thiaj li cov hauj lwm zoo ntawm cov tshuaj. Nyob rau hauv cov ntaub ntawv ntawm uterine ntshav tsim tom qab thaum muaj xwm ceev pov no mas pom zoo txoj kev xeem los ntawm ib tug gynecologist, thiab nyob rau hauv txoj kev ua txhaum lawm ntau tshaj ib lub lim tiam yog tsim nyog los mus ncua cov conception.

Tsuas yog tom qab sib tham thiab qhia kev txiav txim siab gynecologist rau hauv dog dig tus neeg mob, nws yuav ua rau qhov kev koom tes ntawm cov tshuaj rau pov nyob rau hauv hnub nyoog thaum muaj xwm ceev.

Raws li siv yam tshuaj levonorgestrel?

Yuav ua li cas rau hauv lub cev siv cov tshuaj piav, thiab yuav ua li cas kom tsis txhob muaj cov mob tshwm sim los? Yog li ntawd, lo lus nug yog tsa los ntawm ntau. Nruj raws li cov kws muaj txuj tawm tswv yim, hwm ntau npaum thiab ua raws li cov lus qhia - nws guarantees zoo siv ntawm cov tshuaj.

Ua ntej siv, koj yuav tsum xeem kom dhau tus soj ntsuam ntawm cov rog gynecologist, xws li daim tshev mammary qog, pelvic kabmob, ua lub tsev me nyuam smear.

Re-kev soj ntsuam yog nqa tawm tom qab 30-40 hnub tom qab lub installation ntawm ib tug kauv, ces ib xyoos twg, thiab thaum twg muaj ib tug presuppositions - feem ntau. Qhov no intrauterine txoj kev kho yog zoo rau 4 mus rau 5 xyoo. Nws installation yuav tsum hais heev dua lwm yam nrog rau cov kws kho mob specializing nyob rau hauv daim teb no los yog muaj kev nrog qhov suav hais tias tsi ntawm cov tshuaj.

txaus ntshai

Poj niam kev noj tshuaj nrog progestogen, nws yog ua tau qhov kev nce rau ntawm venous thrombosis nyob rau hauv ib tug tseem ceeb lub sij hawm ntawd. Thaum xws li cov tsos mob yog ib qho mob ceev heev yuav tsum tau siv sij hawm ceev kev ntsuas rau mob thiab kev kho mob.

Tom qab tshem ntawm cov rog ntawm nyuam resuscitated tom qab rau lub hlis nyob rau hauv ib nrab ntawm cov poj niam uas thov tom qab 12 lub hlis - ntau tshaj 96 feem pua. Contraceptive orientation yog tsis tshua zoo rau cov neeg mob nrog kev rog.

Contraindications

Wondering "Levonorgestrel - dab tsi yog no lawm?" yuav tsum xav txog tag nrho cov contraindications. Cov lawv:

• Beyond (cus) rhiab heev, tromboflebitnye tsim.
• Thromboembolism, kev hloov nyob rau hauv cov hlab ntsha.
• Cerebrovascular kab mob orientation, cev xeeb tub.
• Hais txog haus: daj ntseg (xws li keeb kwm), pathological mob cov kua tsib tso zis los yog siab, lactation.
• Kev sib deev kom loj hlob.
• Tsis tas li ntawd, rau qhov IUD - node urogenital kab mob recurrences los yog active o nyob rau hauv lub plab mog, excesses postpartum endometritis, mob siab tus kab mob.
• Lub taub dej khawb abortifacient pab nyob rau hauv lub kawg peb lub hlis, dysplastic transformation uterine ncauj tsev me nyuam pathology nyob rau hauv ib tug zoo li los ntshav ntawm tsis paub hais tias keeb kwm, malignancies.
• Tuaj los yog congenital anomalies distorting fibroids.
• Progestagenoz (qog, xws li ib tug ua cancer mis txhab).

txwv

Lub limiting yog feem ntau yam rau kho kev pab mus rau hauv lub tsev me nyuam, qhov chaw yuav yog hais tias koj muaj cov nram qab cov tsos mob los yog mob cov kab mob:

• mob loj heev mob taub hau, ib qho kev thiab lub zos migraine nrog qhov muag plooj tsis pom kev, lwm yam kev mob, teem nyob rau hauv lub tau ntawm coronary artery kab mob;
• ntshiab arterial tawg kev taw qhia, jaundice, complex puas dab nyob rau hauv lub plawv system, xws li plawv thiab cwj nrag;
• mob ntshav qab zib mellitus.

Koj yuav tsum tau sai li sai tau sab laj rau hauv lub Ntaus ntawm cov rog thaum lub sij hawm tsim los yog muaj ntawm tej yam ntawm cov xeev.

Cev xeeb tub thiab lactation lub sij hawm

Txawm tias muaj tseeb hais tias levonorgestrel - ib tug poj niam lawm, nws siv yog tsis tsim nyog thaum lub sij hawm cev xeeb tub. Yog hais tias nws tuaj, nws pom zoo tshem tawm ntawm qhov kev no vim qhov tseeb hais tias tej intrauterine pov tsub kom kev pheej hmoo ntawm ntxov ntxov yug thiab ncuav me nyuam tau. Ua leej niam hnov system los yog tshem tawm tej zaum ua rau miscarriage tshwm sim across. Nws yuav tsum tau tus kws pab tswv yim rau cov feasibility ntawm cov khoom cua txiav ntawm cev xeeb tub nyob rau hauv cov ntaub ntawv ntawm impossibility ntawm muaj tseeb contraceptive extraction.

Thaum nws yog tsis yooj yim sua kom tshem tawm cov intrauterine system thiab ib qho mob ceev muaj siab rau txuag lub cev xeeb tub tus neeg mob yuav tsum tau paub txog cov tau zoo thiab txaus ntshai rau tus me nyuam vim ntxov ntxov yug. Nyob rau hauv xws li mob, koj yuav tsum nco ntsoov soj ntsuam lub cev xeeb tub. Ua ntej tus neeg mob yuav tsum tau coj cov lus qhia tias nws yuav tsum tam sim ntawd qhia txog tag nrho cov tsos mob, uas yuav pab tau kom cov txheej txheem yam tab kaum.

lactation

Thaum pub niam mis thiab siv "Levonorgestrel" hais txog ib feem kaum ntawm ib tug yeeb tshuaj nkag mus rau hauv lub cev tus me nyuam. Pub niam mis rau hauv rau thaum muaj xwm ceev pov yuav tsum tau txiav nyob rau hauv 1.5 hnub.

nyob rau pom zoo ntau npaum rau kho system ntsia tau rau hauv utero, zoo li tej progestogen-tsuas contraceptive txoj kev, nws yog yam ntxwv uas siv cov ib nrab lub hlis tom qab yug tus me nyuam twb tsis muaj kev phiv los ntawm cov kev loj hlob thiab kev loj hlob ntawm tus me nyuam, yog li ntawd, cov tshuaj tsis yog yuav ua rau ib tug uas muaj feem yuav mus rau lub fetus .

phiv cov tsos mob

Thiab rov qab mus rau lo lus nug "Levonorgestrel" - dab tsi nws yog, "cia saib tau tshwm sim thiab contraindications ntawm cov tshuaj Lawv yuav tshwm sim tau nyob rau hauv txawv systems ntawm lub cev thiab yog cov nram qab no cov tsos mob :.

1. Los ntawm lub paj hlwb: nkees, kev nyuaj siab, mob taub hau, mus ob peb vas swings.
2. GIT. Ntuav, kem plab, tu-sauv, tsam plab.
3. Genito-urinary kabmob. Los ntshav, kev sib cais, kev mob, Candidiasis, qhov yuav tshwm ntawm tsim ntawm phem thiab benign qog.
4. Daim tawv nqaij ua pob ua xyua, manifestation ntawm eczema, khaus, tawm pob, pob txuv.
5. Lwm yam: o, ob leeg mob, siab surges, sepsis.

Nyob rau hauv tsawg tus neeg mob qaug dab peg ntawm, qaug dabpeg, tu-sauv thiab tsaus muag.

Thaum lawv tseem nrog lwm yam tshuaj

Kawm "Levonorgestrel" (zoo li cas lawm), nws yog tsim nyog los hais tau ua ke nrog lwm yam tshuaj thiab organic tshuaj. Nyob rau hauv cov ntaub ntawv ntawm lub substance nyob rau hauv lo lus nug nrog inducers ntawm cytochrome P450 isoenzymes yuav txo tau efficiency vim hais tias ntawm ib qho kev nce rau hauv nws cov metabolic dab.

Cov nram qab no tshuaj tej zaum yuav txo cov nyhuv ntawm "Levonorgestrel":

• Group barbiturates, "Tretinoin", "carbamazepine" compositions muaj St. John lub wort thiab nws komponatsiyu.
• Thiaj li muaj cov hauj lwm zoo ntawm anticoagulants, hypoglycemic, anticonvulsant tshuaj.
• "Levonorgestrel" tsub kom lub peev xwm ntawm glucocorticoids nyob rau hauv cov ntshav, thiab kuj muaj peev xwm ntawm cuam tshuam metabolism.
• Vim hluav pw ua niam txiv steroids Recirculation, vim es rov ntawm lub plab hnyuv muaj, muaj zog coj khaub ntshav zaum yuav tshwm sim thaum complex daim ntawv thov ntawm tej yam tshuaj.

Ib tug yuav tsis tab sis ntxiv, sib tham txog yuav ua li cas mus thov "Levonorgestrel" hais tias qhov no tshuaj ua rau ib qho kev nce nyob rau hauv lub sab los ntawm lwm yam tshuaj, ib tug antidote rau nws tsis yog. Nyob rau hauv cov ntaub ntawv ntawm overdose yuav tsum tau symptomatic kev kho mob.