Uas analog "pregna" siv li cas? Piv rau zoo xws li "pregna"

"Pregnil" yog siv nyob rau hauv cov kev kho mob ntawm anovulatory ntxiv lawm tshob rau cov poj niam, nchuav menyuam, samoaborta kev hem thawj, raws li zoo raws li tswj ntawm zes qe menyuam giperstimulirovaniya, induction ntawm ovulation thiab muaj zog tshuaj no ntau ntau. Nws siv zoo nyob rau hauv hloov txoj kev kho tswvyim lutein endogenous lawm mus tsim kho follicular maturation.

Indications rau siv nyob rau hauv cov txiv neej yog ncua tiav nkauj tiav nraug txuam nrog hypofunction ntawm kev sib deev qog, cryptorchidism, impaired spermatogenesis. Xav txog cov feem ntau zoo-paub analogue "pregna" nyob rau hauv no tsab xov xwm.

Hauj lwm "Pregnil" tshuaj

"Pregnil" xws li muaj chorionic gonadotropin (hCG), tib neeg. Qhov no lawm pib tsim chorionic cov ntaub so ntswg ntawm lub kawg ntawm lub embryo implantation txheej txheem. HCG muaj FSH thiab LH ua si tsub kom lub tso pa tawm ntawm cov tshuaj no thiab initiates tus txheej txheem ntawm ovulation. Tom qab nws txhawb haumxeeb corpus luteum kev ua si ua ntej mus rau lub zus tau tej cov estrogens thiab progesterone tsev me nyuam.

Daim ntawv thov ntawm exogenous tib neeg chorionic gonadotropin tsis tau tsuas yog tej lub tso pa tawm ntawm zes qe menyuam tshuaj no thiab progesterone, tab sis kuj induces ovulation, luteal tswj tom ntej bursting follicle.

Siv hCG npaj muaj tus loj tshaj efficiency nyob rau hauv lub Circuit Court nrog lub hom phiaj ntawm tib neeg menopausal lawm thiab follicle.

kiag

"Pregnil" (analogue "pregna" qhua nyob rau tib lub npaum) ua nyob rau ntawm lub noj tshuaj npaum cas ntawm 1500 thiab 5000 MO. Siv rau intramuscular txhaj tshuaj.

Nyob rau hauv cov kev kho mob ntawm anovulatory ntxiv lawm tshob rau cov poj niam pom zoo ib txhaj tshuaj ntawm 5000-10 000 Ministry ntawm kws muaj txuj ci, ntawm qhov kawg ntawm ib lub chav kawm ntawm txoj kev kho ntawm FSH (follicle stimulating hormone) los yog hMG (tib neeg menopausal gonadotropin).

Ua ntej tej, los tswj ntawm zes qe menyuam stimulation yog muab tom qab kev kho mob 5000 MO.

Txhawb lub luteal theem yog nqa tawm los ntawm cyclic txhaj ntawm ib tug ntau npaum ntawm 1000 mus 3000 MO txhua txhua peb lub hnub - 3 lub sij hawm.

Txiv neej siv rau hypofunction ntawm kev sib deev qog thiab ua txhaum ntawm spermatogenesis ntawm koob tshuaj ntawm 1000 mus rau 2000 MO ob peb lub sij hawm ib lub lim tiam (cov analogue ntawm "pregn" yuav tsum noj nyob rau hauv tib txoj kev).

Nyob rau hauv cov kev kho mob ntawm cryptorchidism nyob rau hauv cov me nyuam siv yeeb tshuaj 2 zaug ib lub lim tiam, pom zoo ntau npaum:

- txog li 2 xyoo - 250 MO;

- mus txog rau 6 xyoo mus xaiv 500 rau 1000 MO;

- tom qab 6 xyoo - 1500 MO.

Peb tau suav hais tias yog cov ntaub ntawv ntawm lub tswvyim ntawm cov tshuaj. Tab sis zoo tshaj plaws ntawm tag nrho cov ua ntej pib txoj kev kho sab laj ib tug kws kho mob thiab tau txais ib lub sij hawm los ntawm nws cov tshuaj.

Analogs "pregna»

Yuav ua li cas yog nyob rau hauv kev npaj "Pregnil" counterparts? Nyob rau hauv qhov tseeb, ib tug ntau ntawm lawv, muaj cheaper tshuaj, muaj kim.

"Chorionic Gonadotropin"

"Chorionic Gonadotropin" yog ib tug tsis tshua muaj nqi analogue "pregna." Ua nyob rau hauv ib tug ntau npaum ntawm 500; 1000; 1500 ED. Nws thov intramuscularly. Muab nyob rau hauv ib koob tshuaj ntawm 1500 IU ib hnub twg los yog 3000 IU 2-3 lub sij hawm ib lub lim tiam nyob rau hauv cov kev kho mob ntxiv lawm tshob rau cov poj niam. Nyob rau hauv cov kev kho mob ntawm kev sib deev infantilism taw los ntawm 500 mus rau 1000 IU ib zaug ib lub lim tiam, kev kawm li 2 lub hlis. Cov me nyuam taw 500-1000 MO mus rau kaum xyoo, ces - 1500 IU txog li ib hlis nrog rov kawm. Uas yog, cov tshuaj "Pregnil" analogues yog pheej yig.

"Ovitrel"

"Ovitrel" comprises horiogonadotropin alpha. Ua nyob rau hauv ib tug ntau npaum ntawm 250 micrograms (6500 IU). Nws thov subcutaneously. Nws nkoos hauv lub tsim ntawm corpus luteum, follicle maturation thiab ovulation. 250 g sib npaug zos rau 5000 units ntawm tib neeg chorionic gonadotropin. Thaum stimulation ntawm zes qe menyuam superovulation thiab tau txais 250 .mu.g siv, tom qab lub chav kawm ntawm kev kho los yog tib neeg menopausal FSH. Nyob rau hauv cov kev kho mob ntawm anovulation tshuaj txhaj koob tshuaj rau 1 hnub ua ntej kev sib deev com.

"Horagon"

Lwm analogue "pregna." Muaj nyob rau hauv ib tug ntau npaum ntawm 1500 thiab 5000 MO. Muab intramuscularly. Nws yog siv rau dysmenorrhea, hypoplastic gonads, kev sib deev infantilism leeb tiav nkauj tiav nraug, cov kev hem thawj ntawm txawj rho menyuam, induce superovulation. Yuav kom ntxias superovulation muab nyob rau hauv ib tug ntau npaum ntawm 5,000 rau 10,000 MO ib zaug. Nyob rau hauv cov kev kho mob ntawm npaj rho menyuam nws yog pom zoo kom siv cov thawj hnub ntawm lub tsev lag luam uas cev xeeb tub mus txog rau 14 lub lis piam, ob zaug ib lub lim tiam rau 10 000 MO. hypogonadism kev kho mob muaj txoj kev saib xyuas los ntawm 1,500 mus 6,000 MO ib zaug ib lub lim tiam. Androgen deficiency nyob rau hauv cov txiv neej kho nrog rau cov kev siv ntawm hCG 1 txhua txhua ob lub lis piam rau peb lub hlis.

"Choriomon"

Ua nyob rau hauv ib tug ntau npaum ntawm 5000 IU / ml rau intramuscular thawj coj. Nws yog zoo heev nyob rau hauv cov kev kho mob ntawm anovulatory mus thiab amenorrhoea. Siv nyob rau hauv ua ke nrog nrog tib neeg menopausal gonadotropin (75 MO) mus rau 10 hnub subcutaneously los yog intramuscularly, nyob rau hauv thiaj li yuav nce secretion ntawm estrogens. Thaum ib tug ultrasound mature follicle rau ovulation induction muab los ntawm 5000 mus rau 10 000 MO "Choriomon". Lub tshuaj no yog muab 1-2 hnub tom qab kawg txhaj tshuaj ntawm FSH los yog hMG. Kev sib deev com yog pom zoo nyob rau hauv ib tug txhua txhua hnub kom txog rau thaum ovulation.

Ntxiv lawm tshob vim tsis txaus luteal theem "Choriomon" siv 5000 MO 21, 23 thiab 25 hnub ntawm lub voj voog.

"Profazi"

"Profazi" - analogous mus rau "pregna 5000". Muaj nyob rau hauv ib tug ntau npaum ntawm 2000 thiab 5000 MO. Nws thov intramuscularly. Therapy anovulatory ntxiv lawm tshob yog ua los ntawm plaug 10 000 MT nyob rau hauv nruab nrab ntawm lub voj voog, tom qab kev kho mob nrog HMG los yog FSH. Yuav kom ntxias superovulation taw MO 10000 ib hnub twg rau lub laj kab ntawm lub qe. Thaum lub corpus luteum insufficiency pom zoo thawj coj MO 5000, thiab lub thib tsib mus rau lub cuaj hnub tom qab ovulation. "Profazi" yog zoo heev nyob rau hauv cov kev kho mob ntawm recurrent nchuav menyuam. Nws yog siv los ntawm 10 000 MO nyob rau hauv thawj daim ntawv thov, ces - nyob rau hauv lub 5000 kws muaj txuj ci ob zaug ib lub lim tiam mus txog rau 14 lub lis piam.

Contraindications

Contraindications rau kev siv ntawm hCG npaj:

- lawm.

- hormone-ua hlav ntawm lub qhov chaw mos qog.

- tumor ntawm lub hypothalamus thiab pituitary caj pas.

- hlav ntawm lub tsev me nyuam incompatible nrog cev xeeb tub.

- Thrombophlebitis.

- Congenital Hypothyroidism.

- Thunpas cev xeeb tub keeb kwm rau peb lub hlis ua ntej kev kho mob.

- Polycystic zes qe menyuam.

- lactation.

phiv

Sab los ntawm kev siv ntawm tib neeg chorionic gonadotropin:

- Nce txob taus, kev xav lability, mob taub hau, thiab ntxhov siab vim.

- dyspeptic mob (xeev siab, ntuav).

- Nce rhiab heev ntawm lub txiv mis.

- gynecomastia nyob rau hauv cov txiv neej.

- pob, ua xua.

- Syndrome ntawm zes qe menyuam hyperstimulation.

- Ib qho kev nce ntawm qhov chaw mos, txawv txav erection.

- Yuav txo tau ntawm lub pituitary caj pas.

- Yuav txo tau ntawm circulating ntshav ntim (hypovolemia).

- txuam nrog ntawm cov ntshav nyob rau hauv lub plab kab noj hniav.

- Thromboembolism.

- Ntau cev xeeb tub.

- Dej tuav, qhia, ntau edema.

Analogue "pregna 1500" ices nyob rau hauv congenital tsis xws luag ntawm lub tsev me nyuam, thiab paum appendages, adhesions nyob rau hauv txoj hlab qe menyuam, thawj ntawm zes qe menyuam tsis ua hauj lwm, fibrotic loj hlav nyob rau hauv lub tsev me nyuam.

Tag nrho kev kho mob yuav siv sij hawm qhov chaw nruj me ntsis nyob rau hauv cov kws muaj txuj kev saib xyuas thiab kev tswj ntawm kev hloov nyob rau hauv lub tsom xam, kev siv ntawm cov tshuaj nyob rau hauv lub tsev yog txwv tsis pub thiab tej zaum yuav ua rau kom muaj teeb txim rau kev kho mob.

Kev kho mob ntawm anovulatory ntxiv lawm tshob yuav tsum tau ua nyob rau hauv ultrasound tswj follicle txoj kev loj hlob thiab kev tu ncua kev ntsuam xyuas ntawm lub tsev me nyuam index.

Tseem Ceeb txhua hnub saib xyuas ntawm lub concentration ntawm estradiol. Nrog cov tsos mob ntawm pliaj ntawm zes qe menyuam hyperstimulation kev kho mob chorionic gonadotropin yog tam sim ntawd tshem tawm.

Peb tau pom tias mus rau yeeb tshuaj "Pregnil" analogues, rau kev siv los coj lawv yog kuj piav.