"Cefoperazone + Sulbactam": cov lus qhia rau kev siv, analogs, xyuas

Tam sim no, muaj ib tug lossis loj tus naj npawb ntawm kis kab mob, uas yog yuav luag tsis yooj yim sua lis tsis muaj kev siv ntawm tshuaj tua kab mob. Nws yog ntshaw tias cov tshuaj yog muaj peev xwm kom muaj ib tug tsis ntxim rau ib tug loj tus naj npawb ntawm microorganisms. Cov no muaj xws li ib tug "Cefoperazone + Sulbactam." Ntau ntsib nrog indications rau kev siv ntawm cov tshuaj no.

Tso daim ntawv thiab muaj pes tsawg leeg

Cov tshuaj yog muaj raws li ib tug hmoov rau cov tshuaj. Nws yog tsim los siv intravenously los yog intramuscularly. Lub active tshuaj yog nyob rau hauv ib tug npaum li ntawm ceftazidime 1 g

Tshuaj "Cefoperazone + Sulbactam" (luam lub npe - "Sulperazon" los yog "Sulperatsef") thiab muaj chaw mus rau ib pab pawg neeg ntawm antibacterial tshuaj.

Lub pharmacological kev txiav txim ntawm cov tshuaj

Qhov no tshuaj yog ib tug ua ke txhais tau tias. Medicament "Cefoperazone" yog ib tug broad-spectrum tshuaj tua kab mob. Nws tau muaj ib yam tsis zoo rau feem ntau aerobic thiab co kab mob kab mob.

Kev npaj "Sulbactam" yog ib tug irreversible inhibitor ntawm beta-lactamases. Nws tiv thaiv kev puas tsuaj ntawm penicillins thiab cephalosporins, txij thaum lub compound teev Synergy nrog lawv.

Lub medicament "Cefoperazone + Sulbactam" niamntiav nws phiv ntxim rau cov hlwb los ntawm inhibiting peptidoglycan, uas yog ib tug indispensable ib feem ntawm cov kab mob phab ntsa.

Drug tas los rau ntawm lub cev nyob rau hauv txog 8 teev ntawm cov zis. Lub ib nrab-lub neej txog ntawm ob teev. Yog hais tias ib tug neeg mob uas tau txais cov tshuaj, kev txom nyem siab tus kab mob, thaum cov tshuaj feem yuav tsub kom.

Code JECFA "Cefoperazone + Sulbactam» - 24.42.11.228. Tshuaj ua nyob rau hauv Is Nrias teb.

Indications rau kev siv ntawm cov tshuaj

Cov tshuaj no yog qhia rau lub xub ntiag ntawm kis kab mob uas yog txhais los ntawm kab mob rhiab rau lub active tshuaj. Cov muaj xws li:

• Pharyngitis.
• Tonsillitis.
• Mob ntsws.
• o ntawm lub ntsws.
• Lung rwj.
• Cov kab mob ntawm cov mob txeeb system, xws li cystitis, gonorrhea, prostatitis, vulvovaginal.
• ENT kab mob.
• Ntawm daim tawv nqaij cov kab mob ntawm cov kab xwm: furunculosis, pyoderma, ua paug thiab lwm tus neeg.

• Cov kab mob tsis pub dhau lub ob leeg.
• Sepsis.
• Meningitis.

Cov tshuaj no kuj coj raws li ib tug tiv thaiv kev ntsuas kab mob mob tom qab phais.

Kev npaj "Cefoperazone thiab Sulbactam Dzhodas" yog tseem pom nyob rau hauv peritonitis, cholecystitis, cholangitis thiab lwm yam intra-plab kab mob. Lub hom phiaj ntawm tshuaj discovery thiab ntev ntawm txoj kev kho thiab kev kho mob kiag yuav tsum tau koom nyob rau hauv tsuas yog tus kws kho mob.

Txhais tau hais tias "Cefoperazone thiab Sulbactam Spencer" yog tseem muab rau rau hauv lub hom phiaj ntawm kev tiv thaiv.

Leej twg tsis pom zoo kom noj cov tshuaj

Dua li ntawm qhov ntau ntawm cov kev ua, qhov cuab tam yuav tsis tau txais nyob rau hauv tej yam tej yam kev mob:

• Nyob rau hauv lub xub ntiag ntawm npau taws me ntsis mus rau yeeb tshuaj.
• Thaum lub sij hawm pub niam mis "Cefoperazone + Sulbactam" yog tseem txhob.
• Raum hepatic tsis ua hauj lwm yuav tsum tau ceev faj heev daim ntawv thov.
• Nyob rau hauv lub xub ntiag ntawm plab nyob rau hauv ib tug neeg mob lub keeb kwm.

Ua ntej yuav pib kev kho mob nrog cov tshuaj no koj yuav tsum nco ntsoov tham nrog koj tus kws kho mob lub xub ntiag ntawm contraindications.

Undesirable los thaum lub sij hawm txoj kev kho

Tshuaj "Cefoperazone + Sulbactam" trade lub npe yog "Sulperazon" thaum lub sij hawm kev kho mob yuav ua rau lub manifestation ntawm cov nram qab no tshwm sim tsis zoo:

• Los ntawm cov urinary system yuav tsim hematuria.
• Plawv system yuav teb mus rau ib tug txo nyob rau hauv cov ntshav siab los yog vasculitis.

• Analysis ntawm cov ntshav thaum lub sij hawm txoj kev siv tshuaj feem ntau qhia ib tug txo ntawm hemoglobin, txo hematocrit, thrombocytopenia, eosinophilia, leukopenia thiab lwm yam kev txawv txav.
• Txo albumin theem.
• Bilirubin encephalopathy nyob rau hauv tus me nyuam mos cov me nyuam mos yuav ua tau nrog daj ntseg.
• Nyob rau hauv ib feem ntawm tus mob huam tej zaum yuav dyspepsia, ntuav, xeev siab, thiab pseudomembranous mob plab.
• Nyob rau hauv daim tawv nqaij yuav tshwm sim pob, maculopapular pob, thiab mob khaus.
• Kuaj cov kev tshawb fawb tau qhia ntau zog cov nqi ntawm daim siab kev ua kev ntsuam xyuas.
• Cov kev txhaj tshuaj site ce cov tshuaj, thaum muab intravenously los ntawm cov catheter - phlebitis.
• Tsawg kawg yuav muaj kev mob taub hau, ua npaws, thiab lwm yam anaphylactic tshua ntawm tus kab mob.

Thaum tshwm sim ntawm tej undesirable ces yuav tsum sib tham txog qhov teeb meem no nrog koj tus kws kho mob. Tej zaum koj yuav muaj mus rau reconsider ntau npaum ntawm cov tshuaj "Cefoperazone nrog sulbactam" los yog rho nws zoo rau nws.

Yuav ua li cas yuav muab tau leej twg nrog ib tug overdose ntawm cov tshuaj

Yog hais tias koj noj cov tshuaj no nyob rau hauv cov nruj kev saib xyuas ntawm ib tug kws kho mob, cov overdose koj yuav tsum tsis txhob txhawj, tab sis rau nws tus kheej-txoj kev kho yog feem ntau tau. Yog hais tias lub cev tau txais cov tshuaj ntau npaum li cas tshaj yog yuav tsum tau, tej zaum yuav muaj neurological mob, xws li mob chua leeg.

Kev kho mob nyob rau hauv cov ntaub ntawv no yog nqa tawm nyob rau hauv raws li nrog cov tsos mob. Qhov zoo tshaj yog hemodialysis.

Ntau npaum thiab kev kho mob regimen

Yog hais tias tsa tshuaj "Cefoperazone + Sulbactam" phau ntawv qhia xav kom txhaj cov tshuaj intravenously los yog intramuscularly. Rau cov neeg laus cov neeg mob ib tug txhua txhua hnub koob tshuaj no feem ntau yog los ntawm 2 mus rau 4 grams ntawm lub active ingredient. Cov nyiaj no yuav tsum tau muab faib mus rau hauv ob ua sawv.

Yog hais tias ib tug neeg mob muaj ib tug loj heev kab mob tshuaj yuav tau nce mus 8 grams, uas yuav tsum tau muab faib ua ob zaug ib hnub twg. Yog hais tias muaj yog tsis muaj lwm yam kev mob, feem ntau ntawm cov neeg mob, thiab txhua hnub koob tshuaj nyob rau hauv tus nqi ntawm cov 12-16 grams tso tsis khees phiv.

Lub caij ntawm txoj kev kho yog txiav txim los ntawm tus kws kho mob. Piv txwv li, thaum uncomplicated gonococcal urethritis muab ib-lub sij hawm 500 mg ntawm cov tshuaj.

Nrog rau cov aim ntawm kev tiv thaiv muaj teeb meem tom qab phais npaj los siv rau cov neeg mob 1-2 g intravenously ib teev ua ntej lub lag luam. Qhov no tshuaj tej zaum yuav tau rov qab tom qab 12 teev. Yog hais tias kev phais yog ua nrog kev raug mob muaj teeb meem xws li tus kab mob, lub prophylactic thawj coj tseem rau 3 hnub tom qab lub rooj sib tham.

Cov neeg mob uas muaj teeb nyob rau hauv lub raum, cov tshuaj "Cefoperazone + Sulbactam" yog muab nyob rau hauv ib tug ntau npaum ntawm tsis ntau tshaj 4 grams tauj ib hnub. Yog hais tias muaj teeb meem nrog lub siab, lub koob tshuaj yog txo txawm ob npaug.

Txij li thaum cov tshuaj yuav tsum muab intravenously thiab intramuscularly, muaj ib co nta nyob rau hauv nws daim ntawv thov.

Thaum muab intravenously li ib tug hnyav rau cov hmoov yuav siv tau:

• 5% dextrose tshuaj.
• Nyoj.
• Muaj menyuam tsis taus dej rau txhaj tshuaj.

Thaum muab intravenously, cov hmoov nyob rau hauv ib tug minyuam lam fwj tshuaj yuav tsum ua neej nyob hauv 10 ml ntawm ib tug haum kuab. Nws yog tsim nyog yuav tau tos rau tag nyias mus nyias thiab cov tshuaj muab maj mam 3-5 feeb.

Yog hais tias yuav nrog kua tshuaj "Cefoperazone + Sulbactam" phau ntawv qhia kom 1 gram ntawm lub active ingredient. Ntawd ces yog txheem ntawm ib vial ua neej nyob hauv 5 ml ntawm dej rau txhaj, thiab ces ntxiv mus rau lub Txoj kev lis ntshav tov, nqa lub concentration rau 20-100 mg / mL. Muab tus nqi ntawm cov tshuaj rau nrog kua, manipulation lub sij hawm tej zaum yuav tsum yog los ntawm 10 mus rau 30 feeb.

Intramuscular cov thawj coj mus yaj cov hmoov tej zaum yuav siv los sis dej rau txhaj los yog sodium tshuaj dawb. Qhov ratio yog feem ntau yog siv raws li nram no: 0.5 g khoom noj 2 mL ntawm kuab.

Txij thaum muab cov tshuaj feem ntau tshwm sim mob ntawm lub qhov koob, nws yog pom zoo kom hais tias nyob rau hauv qhov kev npaj ntawm cov tshuaj tov ntxiv "lidocaine 2%", tab sis tsuas yog nyob rau kev mob uas tus neeg mob yog tsis haum rau cov tshuaj.

Rau tej kab mob tshuaj muab ib tug zoo ntxim yog sai, ces tus tshuaj yog muab nyob rau hauv "Cefoperazone + Sulbactam." Ntsiav tshuaj kuj npaum li cas qeeb qeeb.

Siv cov tshuaj nyob rau hauv cov me nyuam

Cov me nyuam feem ntau txom nyem los ntawm kis kab mob rau cov uas tsis muaj tshuaj tua kab mob tsuas yuav tsis ua li cas. Lub sij hawm koob ntawm cov active tshuaj cefoperazone tub ntxhais yuav tsum yog los ntawm 50 mus rau 200 mg rau ib kilogram lub cev hnyav ntawm tus me nyuam. Muab tshuaj yuav tsum sib npaug qhov chaw los ntawm nkauj nraug mus rau hauv ob ua sawv.

Desirably, txhua hnub koob tshuaj yuav tsis pub tshaj 12 F. Yog hais tias cov tshuaj yog txhaj bolus, lub tsev koob tshuaj yuav tsum tsis txhob ntau tshaj 50 mg / kg.

Me nyuam mos cov me nyuam mos kuj yuav muab 50-200 mg ntawm cov tshuaj rau ib kilogram lub cev hnyav, faib nws mus rau hauv ob ua sawv los ntawm 12 teev. Raws li nyob rau ntau lub xyoo ntawm ua daim ntawv thov ntawm lub cuab tam nyob rau hauv cov kev kho mob ntawm cov me nyuam, nws yuav tau hais tias koob tshuaj mus txog rau 300 mg rau ib kilogram ntawm lub cev hnyav ib hnub twg yog zoo zam los ntawm cov me nyuam, txawm nyob rau hauv lub xub ntiag ntawm cov kab mob meningitis.

Siv cov tshuaj thaum lub sij hawm cev xeeb tub

Tshuaj nrog active ingredient ceftazidime yuam rau cov poj niam nyob rau hauv txoj hauj lwm tsuas yog thaum xws xeev nyob qhov twg cov kev pab cuam rau cov expectant niam ob peb lub sij hawm ntau tshaj lub peev xwm uas yuav muaj rau lub tus me nyuam. Yog hais tias koj xav thov cov tshuaj thaum lub sij hawm lub mis noj, tus kws kho mob yuav pom zoo kom lub sij hawm no mus rau cov hloov tus me nyuam mus dag noj.

Sis nrog lwm yam tshuaj

Tshuaj "Cefoperazone" nyob rau hauv nws pharmacological khoom no tsis nrog ib tug aminoglycoside. Yog hais tias muaj yog ib tug yuav tsum tau nyob rau hauv txoj kev kho ntawm cov ob pawg ntawm cov tshuaj, lawv muab nyob rau hauv daim ntawv ntawm cov quas ntus thawj coj ntawm ob lub cais catheter.

Co-thawj coj ntawm cov tshuaj nrog ib tug thrombolytic, antiplatelet thiab narcotics yuav muab tsub kom qhov uas yuav los ntshav.

Rau cov neeg mob uas raum teeb meem nyob rau hauv lub txais tos ntawm ib tug medicament "Cefoperazone Sulbactam" ua ke nrog aminoglycosides thiab diuretics fraught txoj kev loj hlob ntawm nephrotoxicity.

Thaum lub sij hawm txoj kev kho nrog "Cefoperazone" undesirable rau haus dej haus cawv, txwv tsis pub nws yuav ua raws li nram no cov tsos mob:

• Xeev siab.
• Ntuav.
• Mob taub hau.
• Tachycardia.
• txos cov ntshav siab.
• Mob plab.

Ua ntej koj yuav pib kho nrog cov tshuaj no, koj yuav tsum qhia rau koj tus kws kho mob txog txhua yam tshuaj ua npaum li cas thaum lub caij.

Yuav ua li cas yog hais tias koj txhob txhais tau tias "Cefoperazone"? Analogs yuav zoo hloov nws.

Ib txhia nuances ntawm kev siv cov tshuaj

Thaum lub sij hawm kev kho mob nrog cov tshuaj no yuav tsum tau tshwj xeeb tshaj yog ceev faj rau cov neeg mob uas muaj kev tsis haum tshuaj yog feem ntau pom. Cov kev pheej hmoo ntawm no nce rhiab heev yog fraught nrog txawm tuag taus. Yog hais tias thaum lub sij hawm txoj kev kho cai txawm me tsis haum tshuaj loj, cov tshuaj "Cefoperazone + Sulbactam" yuav tsum raug rho tawm tam sim ntawd thiab muab nws hloov los ntawm lwm cov txhais tau tias.

Yog hais tias tus neeg mob muaj ib tug loj heev degree muaj dab tsi thaiv ntawm lub biliary ib ntsuj av tau, daim siab kab mob thiab lub raum, nws yuav tsum tau ib tug neeg koob tshuaj hloov teeb meem. Nyob rau hauv lub xub ntiag ntawm lub raum thiab hepatic puas yuav tsum tsis tu ncua saib xyuas lub concentration ntawm active tshuaj tshuaj nyob rau hauv lub ntshiab. Txawm tsis muaj tus tswj koob tshuaj yuav tsum tsis txhob ntau tshaj 2 gram ib hnub twg.

Nyob rau hauv ib co neeg mob thaum lub sij hawm kev kho mob nrog "Cefoperazone" tsim vitamin K deficiency Feem ntau cov feem ntau, qhov teeb meem no nyob rau hauv cov neeg uas muaj ib tug puas noj cov zaub mov, malabsorption, los yog kev txom nyem rau ib tug ntev lub sij hawm yog nyob rau tso dej noj. Cov neeg mob uas raug kho nrog anticoagulants, rau qhov yuav tsum tau saib xyuas cov prothrombin lub sij hawm, thiab, yog tias tsim nyog, taw ib tug ntxiv kom tsawg ntawm cov vitamin K.

Yog hais tias koj xav tau ib tug ntev chav kawm ntawm kev kho mob, "Cefoperazone", nws yog ua tau rau kom cov micro-kab uas tsis yog raug rau no medicament. Nws yuav tsum tau ib tug periodic xyuas ntawm kev ntsuas ntawm tus hauj lwm ntawm sab hauv nruab nrog cev, tshwj xeeb tshaj yog lub siab, ob lub raum thiab hematopoiesis. Qhov no yog tshwj xeeb tshaj yog ib qho tseem ceeb nyob rau hauv cov kev kho mob ntawm neonates, cov me nyuam mos cov me nyuam mos thiab cov me nyuam mos yug ntxov.

Thaum lub sij hawm kev kho mob yuav tsum caiv txhob tsav tsheb thiab kev ua tau zoo paub tab uas yuav tsum tau ntau concentration.

tshuaj analogues

Yog hais tias peb xav txog tej yeeb tshuaj, ob pawg yuav tau hais kev npaj rau nws analogs thiab txhais. Rau lus muaj xws li cov tshuaj uas nyob rau hauv lawv cov muaj pes tsawg leeg muaj tib lub active ingredient. Rau "Cefoperazone" yeeb tshuaj, cov no yog cov:

• "Bakperazon".
• "Sulzontsef".
• "Sulmomer".
• "Sultsef".
• "Tsebaneks".
• "Paktotsef" thiab lwm tus neeg.

Yog hais tias peb los sib piv cov medicament "Cefoperazone" analogs yuav muaj ntau ntxiv Cheebtsam, uas ua ke nrog ib tug yooj yim tshuaj muaj ib tug me ntsis txawv nyhuv. Uas yog vim li cas cov kev xaiv ntawm xws tshuaj yuav tsum tau mus them thiab txais lawv tsuas yog nyob rau cov tshuaj.

Lwm pab pawg neeg ntawm analogues yog tshuaj nrog tib pharmacological kev txiav txim. Yog hais tias koj noj cov tshuaj "Cefoperazone + Sulbactam" analogues ntawm no pab pawg neeg yog:

• Hmoov "Azaran" tso dej raws leeg xav tshuaj.
• "Axons."
• Hmoov cov kev txhaj tshuaj "Bestum".
• "Vitsef".
• "Klaforan".

• "Kefoteks".
• "Tsedeks" tsiav tshuaj.
• "Tsemideksor" (ntsiav tshuaj).
• "Tsefantral" thiab ntau lwm tus neeg.

Txawm muaj tib pharmacological los ntawm cov tshuaj vim hais tias ntawm qhov sib txawv active tshuaj yuav muaj sib txawv los ntawm lub cev, yog li tsis txhob xaiv lawv tus kheej cov tshuaj, raws li nyob rau hauv cov lus qhia rau kev siv.

Testimonials

Cov neeg mob uas tsis ib zaug resorted mus rau "Cefoperazone + Sulbactam" tshuaj rau cov kev kho mob ntawm kis kab mob, muab sau nws cov high efficiency. Muaj ntau cam hais tias genitourinary kab mob kho tau sai sai thiab tsis muaj teeb meem.

Kuv niam me nyuam tawm pro tshuaj "Cefoperazone" haum zoo xyuas. Lawv pom tias cov me nyuam zam lub tshuaj zoo txawm nyob rau hauv lub xub ntiag ntawm co-morbidities. Nws yuav tsum tau recalled hais tias xws li kev kho yuav tsum tau ua xwb nyob rau hauv lub tsev kho mob, tshwj xeeb tshaj yog nyob rau hauv cov me nyuam mos.

Cov kev txais neeg kawm ntawm tej tshuaj tua kab mob yuav tsum tau ntau xim rau kev ua hauj lwm ntawm lub digestive system. Kom muaj qhov nqi koj tshuav ntawm lub microflora, nws yog ntshaw kom ib txhij tau txais kom tsim nyog cov tshuaj, piv txwv li, "Linex". Lo lus nug no yeej ib txwm yuav sib tham nrog koj tus kws kho mob.