Insomnia muaj peev xwm ua rau tus kab mob Alzheimer

Insomnia thoob plaws hauv lub hmo ntuj thiab nyob twj ywm thaum lub sij hawm lub hnub nyob rau hauv ib tug daze ... Muaj coob tus neeg nyuaj siab nrog rau tej kev muaj insomnia. Raws li kev tshawb fawb tshiab, tsis zoo pw tsaug zog thiab nruab hnub tsaug zog yuav ua rau kom txoj kev pheej hmoo ntawm kev tsim Alzheimer tus kab mob.

Ib tug interesting txoj kev tshawb no

101 cov neeg raug caw tuaj rau lub txoj kev tshawb no. Tag nrho cov neeg twb tsis tau pom tej peev xwm puas. Lub hnub nyoog ntawm yaam kws yog 63 xyoo.

Tom qab qhov xyaum ua tej, cov neeg koom sau ib cov lus nug hais txog qhov zoo ntawm lawv cov pw tsaug zog, lawv txhua tus dhau rau lawv cov qauv ntawm cov leeg nrob kua. Lub hom phiaj ntawm tus tsom xam yog qhia hais tias yuav muaj cov kev xeem plaques, uas yog hallmarks ntawm tus kab mob Alzheimer. Zaum tuaj mus rau lub xaus hais tias ib tug uas tsis muaj cov pw tsaug zog zoo thiab nruab hnub tsaug zog txuam nrog nce cov nqi ntawm tus kab mob loj heev.

Nyhuv ntawm beta-amyloid nyob rau hauv qhov tshwm sim ntawm plaques nyob rau hauv lub hlwb

Thaum cov kev txuas ntawm tsis muaj cov pw tsaug zog thiab dementia yog tsis tau 100% tseeb, ob peb cov kev tshawb fawb nyob rau hauv cov tsiaj tau pom tias thaum lub sij hawm pw tsaug zog lub hlwb muaj peev xwm cais tawm toxins xws li beta-amyloid (toxic cov nqaijrog) pab txoj kev. Lawv ntxias cov tsos ntawm plaques nyob rau hauv lub hlwb ntawm cov neeg mob uas tsis nco tus neeg mob, thiab tej zaum hais tias yog raws nraim tib yam txheej txheem tshwm sim nyob rau hauv tib neeg. Introduction ntawm amyloid nyob rau hauv lub hlwb cov ntaub so ntswg yog thawj lub npe hu preclinical theem ntawm tus kab mob Alzheimer thiab tshwm sim ua ntej cov tsos ntawm cov tsos mob ntawm dementia.

Tag nrho cov kev tshawb koom tau pom tias muaj tej yam kev tsis nco qab. Raug coj mus rau hauv tus account genetic tom qab, tsev neeg keeb kwm thiab cov ntaub ntawv nyob rau hauv APOE noob, uas yog txuam nrog ib tug ntau dua qhov muaj tseeb ntawm extinction ntawm kev puas hlwb kev ua si. Txhua tus neeg muab nws kev soj ntsuam ntawm tus xov tooj ntawm cov sij hawm ntawm pw tsaug zog, pw tsaug zog zoo thiab nruab hnub tsaug zog xwb.

"Cov neeg koom nyob rau hauv txoj kev tshawb no twb kam mus yauv mus ib lumbar tej nam kev tshawb fawb mus rau hauv lub ua tus kab mob Alzheimer - hais tias senior sau Barbara Bendlin scientific ua hauj lwm ntawm lub kev tshawb fawb Center ntawm Kab Mob nyob rau hauv Wisconsin. - Analysis ntawm cov kua tso cai rau peb kom peb saib cov markers txuam nrog tus kab mob Alzheimer li quav hniav, raws li zoo raws li ntsuas mob thiab paj ntawm tes puas tsuaj. "

Tsis pw tsaug zog ua tus kab mob yog tsis nyob rau hauv tag nrho cov mob

Nws yuav tsum tau muab sau tseg tias tsis tag nrho cov uas muaj teeb meem nrog pw tsaug zog, tsim Alzheimer tus kab mob. Barbara Bendlin, uas yog ib qho kev pab xib fwb ntawm cov tshuaj nyob rau University of Wisconsin School of tshuaj, hais Lub New York Times: «Peb soj ntsuam cov pab pawg neeg thiab feem ntau nquam paj nquam nruas kev sib raug zoo ntawm cov neeg pluag pw tsaug zog nrog npiv zas ntawm neurodegeneration. Tab sis thaum koj saib cov neeg, tsis nyob rau hauv tag nrho cov hnov xub ntiag ntawm insomnia. "

Sim kawm rau nas

Qhov tseeb kev tshawb no yog ib tug continuation ntawm ua ntej lawm kev tshawb tawm tswv yim hais tias disturbed pw tsaug zog yuav ua tau ib tug ua ntawm dementia. Lwm yam kev tshawb fawb tau pom kev mus ntawm tus kab mob pw tsis taus thiab txoj kev loj hlob ntawm amyloid plaques. Kev tshawb fawb nyob rau hauv nas tsom tias cov tsiaj uas pw, cov theem ntawm beta-amyloid twb txo. Sau kom tiav so zoo clears lub hlwb ntawm nas los ntawm tej yam tshuaj lom.

Bendlin thiab nws lug txhawb cov miv soj ntsuam cov neeg uas muaj feem yuav tsis nco qab tus kab mob. Cov pej xeem yuav tsum xyuas nyob rau hauv ib tug pw tsaug zog kuaj, qhov twg lub hom phiaj kev ntsuam xyuas yuav tsum tau nqa tawm.

Tiv thaiv kom txhob tej kev txhim kho nyob rau hauv pw tsaug zog zoo kev loj hlob ntawm tus kab mob?

"Yog hais tias nws hloov tawm hais tias muaj kev cuam tshuam, uas yuav tshem tawm ib tug pathological mob zoo li insomnia, ua rau lub fact tias nyob rau hauv lub hlwb yuav tsum tso tsawg amyloid, nws yuav muab muaj zog them nyiaj yug rau qhov kev siv ntawm chav ntsuas ua ntej cov neeg yuav pib mus qhia kev txawj ntse poob txuam nrog tus kab mob Alzheimer "- Bendlin hais tias.

Bendlin kuj sau ntawv hais tias ua ntej hais kom ib tug neurologist tias nws tau sau rau koj ib tug pw tsaug zog ntsiav tshuaj, koj yuav tsum tau paub xyov seb cov tshuaj los daws pw tsaug zog nyob rau hauv lub amyloid influences. Cov kauj ruam tom ntej yuav ua tau mus ntxiv muab tshuaj nyob rau hauv raws li qhov ntsuas no.