"Insulin isophane": cov lus qhia rau kev siv, analogs

Mob ntshav qab zib - ib tug mob loj, uas, Tu siab, tsis tau muab tshem tawm kiag li. Raws li koj paub, nyob rau hauv keeb kwm yav dhau ntawm tus kab mob muaj yog ib tug ua txhaum ntawm hormonal secretion nyob rau hauv pancreatic ntaub so ntswg. Thiab cov neeg mob feem ntau muab hluavtaws insulin "Isophane". Qhov no cov ntaub ntawv uas lwm yam cov theem ntawm qab zib nyob rau hauv cov ntshav, kom ntseeg tau lub lag luam ntawm tag nrho cov kab mob.

Ntawm cov hoob kawm, cov neeg mob xav nyob rau hauv tej ntaub ntawv qhia ntxiv txog cov tshuaj. Raws li muaj feem xyuam rau lub cev semi-hluavtaws insulin "Isophane"? Cov lus qhia, contraindications, tau teeb meem thaum lub sij hawm txoj kev kho - ib tug tseem ceeb point, uas yuav tsum tau los sib tham nyob rau hauv tsab xov xwm.

tso tawm daim ntawv

Nws yog tsis muaj daim card uas mob ntshav qab zib yog ib qho thiab txaus ntshai tus kab mob uas yuav tsum tau siv los ntawm ntau yam tshuaj, xws li insulin. "Isophane" - cov lag luam tawm lub npe ntawm cov tshuaj, uas yog ib tug semi-npaj sib tov ntawm cov tshuaj hormones. Qhov tshuaj nyob rau hauv daim ntawv ntawm ib tug tov rau subcutaneous thawj coj. Cov tshuaj no yog muag nyob rau hauv lub khob vials ntawm 10 ml koob 40ME / ml. Yuav kom npaj cov tshuaj siv lim dej rau txhaj tshuaj.

Yog hais tias lwm yam tshuaj nrog rau cov tib muaj pes tsawg leeg thiab cov khoom raws li cov insulin "Isophane". Txhais nws - nws 'Insuman', 'Protafan "thiab" Himulin ". Nws yuav tsum tam sim ntawd yuav hais tias hais tias xws li tshuaj dispensed los ntawm cov tshuaj nkaus xwb, los yog muab lawv ib tug endocrinologist.

Yuav ua li cas lub zog ntawm cov tshuaj?

Insulin "Isophane" yog ib tug semi-hluavtaws lawm uas muaj tib lub zog li lub tshuaj ua los ntawm cov tib neeg txiav. Cov tshuaj thiaj li tus nqi ntawm cov piam thaj nyob rau hauv cov ntshav los ntawm strengthening cov txheej txheem ntawm lipogenesis thiab gluconeogenesis.

Khoom cua tshuaj ua num ua ke nrog insulin receptors ntawm cell week, activating metabolic dab nyob rau hauv lub cell. Tom qab haus synthesis cai kom cov tej yam enzymes, xws li glycogen, pyruvate kinase thiab hexokinase.

Cov nyhuv yuav tsum muaj cai tom qab xwb 1-1.5 xuab moos tom qab thawj coj ntawm cov tshuaj. Nyob ntawm seb cov tshuaj thiab lub cev ntawm tus neeg mob lub maximal kev ua ntawm cov khoom cua insulin cai tom qab 4-12 teev tom qab thawj coj. Cov nyhuv kav los ntawm 11 mus rau 24 teev.

Lub ntsiab indications rau kev siv

Kev npaj "Insulin Isophane" yog siv nyob rau hauv lub thib ob hom mob ntshav qab zib (insulin-dependent daim ntawv no). Nws kuj yog siv rau ib ntus insulin. Tej zaum li ib tug kev kho mob yuav tsum tau thiab muaj ntshav qab zib thawj hom. Piv txwv li, cov kev taw qhia ntawm cov tshuaj pom zoo kom hais tias cov neeg mob thaum hypoglycemic agents tsis muab cov nyhuv.

Cov kev taw qhia ntawm tib neeg insulin yog yuav tsum tau tom qab tej yam kev phais cov txheej txheem. Qhov no tshuaj yog siv thiab gestational mob ntshav qab zib mellitus (daim ntawv no ntawm tus kab mob no tshwm sim nyob rau hauv cov poj niam thaum lub sij hawm cev xeeb tub). Insulin niam pom zoo kom hais tias yog noj cov zaub mov kho tsis muaj cov yam nyhuv.

Semi-hluavtaws insulin "Isophane": cov lus qhia rau kev siv

Nyob rau hauv lub thib ob hom mob ntshav qab zib cov neeg mob yuav tsum tau tag lub neej kev kho mob. Koob hnub npaum li cas, lub sij hawm ntawm thawj coj - tag nrho cov no yog txiav txim los ntawm koj tus endocrinologist. Nws yog ib qho tseem ceeb rau nruj me ntsis raws li tag nrho cov kev cai. Muaj ib co kev cai rau kev siv cov tshuaj "Insulin Isophane".

• Cov tshuaj yog tsim los thiaj tau tuaj rau subcutaneous thawj coj. Nyob rau hauv tsawg tus neeg mob, koj tus kws kho mob tej zaum yuav pom zoo kom koj cov tshuaj muab intramuscularly. Tso dej tshuaj txwv tsis pub.
• Cov tshuaj yuav tsum tsis txhob yuav muab nyob rau hauv tib lub qhov chaw.
• Ua ntej peb yuav tsum tuav tus vial ib tug ob peb lub sij hawm, thiab ces hu cov yam nqi ntawm cov tshuaj koob txhaj (tshuaj tom ib lub zuj zus).
• Cov kev txhaj tshuaj yuav tsum tau nqa tawm sai li sai tau tom qab sau tus syringe.

Lub vials nrog cov tshuaj muab cia rau hauv ib lub tub yees nyob 2-8 degrees Celsius. Ua ntej cov kev taw qhia ntawm cov tshuaj yog tsim nyog los ntsuas cov ntshav qab zib theem. Nyob rau hauv tsis muaj cov ntaub ntawv yuav siv tsis tau cov tshuaj yog tias koj pom tus turbidity ntawm cov tshuaj, lub tsim ntawm deposits rau ntawm phab ntsa ntawm lub raj mis.

Puas muaj tej contraindications?

Cov tshuaj no muaj ib co contraindications - cov ntaub ntawv muaj cov lus qhia rau kev siv. "Insulin Isophane" yog tsis siv nyob rau hauv cov neeg mob uas hypoglycemia. Contraindications koom insulinoma thiab npau taws me ntsis mus rau yeeb tshuaj cov khoom xyaw. Nws yuav tsum tau muab sau tseg hais tias tej zaum hloov txhaj tshuaj site yuav ua nyob rau hauv ib tug tsis haum cov tshuaj tiv thaiv thiab cov tsos ntawm lwm yam kev phiv.

Tej kev phiv

Tej kev npaj no yog tsim nyog nyob rau hauv cov neeg mob uas insulin-dependent mob ntshav qab zib mellitus. Txawm li cas los txoj kev kho yog txuam nrog ob peb lwm yam mob. Uas ua txhaum yuav raug nyob rau kev siv ntawm cov tshuaj "Isophane Insulin"? Phau Ntawv Qhia no muaj cov lus qhia nram qab:

• Mus rau daim ntawv teev cov feem ntau mob muaj xws li kev tsis haum tshuaj, uas yog nrog cov tsos ntawm cov pob, thiab urticaria, ib tug ntse poob nyob rau hauv cov ntshav siab, muaj zog lub cev kub thiab cov tsos ntawm edema.
• Nyaum txim ntawm insulin txoj kev kho yog hypoglycemia - ib tug mob yus muaj los ntawm ib tug txo nyob rau hauv cov ntshav qab zib theem. Cov tsos mob muaj xws li tawv nqaij daj, ceev ceev lub plawv dhia, ntxhov siab vim, pw tsaug zog teeb meem, qhov kev xav ntawm kev tshaib kev nqhis. Xws li ib tug ua txhaum yog feem ntau vim tsis yog ntau npaum, los yog tsis ua hauj lwm ua raws li tus kws kho mob cov lus qhia. Nyob rau hauv lub feem ntau loj heev zaum, nws muaj hypoglycemic coma.
• Pib ntawm kev kho mob nyob rau hauv ib co neeg mob txuam nrog pom tau qhov sib puas. Npaum li cas txhawj txog nws tsis nqi nws, vim hais tias nyob rau hauv Feem ntau, cov kev phiv mus tam sim ntawd rau lawv tus kheej.
• Mus rau daim ntawv uas tau teeb meem muaj xws li immunological tshua, uas yog tseem kuaj raws li kom pab tau rau lub cev zoo ntawm cov insulin.
• Thaum pib ntawm lub tshuaj tau daim tawv nqaij tshua, xws li liab thiab khaus. Lawv kuj kis tau rau lawv tus kheej.
• Cov kev taw qhia ntawm loj heev koob tshuaj yog fraught nrog kev puas hlwb kev ntshawv siab. Muaj yog nce txob taus, ntxhov siab vim, kev coj cwj pwm hloov, txoj kev loj hlob ntawm kev nyuaj siab.

Nws yog to taub hais tias cov kev taw qhia ntawm insulin "Isophane" yuav tsum raws li lub sij hawm twv los ntawm tus kws kho mob. Hla txhaj nrog txoj kev loj hlob ntawm ntshav qab zib acidosis.

Insulin "Isophane": counterparts

Nyob rau hauv niaj hnub tshuaj, khoom cua tib neeg insulin (luv luv- thiab medium-lub sij hawm raug) yog siv los tswj cov zib theem ntawm cov tib neeg lawm analogs, thiab mixtures thereof. Ntawm cov hoob kawm, tus kws ua lag luam muaj ib tug ntau ntawm cov tshuaj los pab mus ib ntus tshem tawm cov tsos mob ntawm cov ntshav qab zib.

Mus rau daim ntawv teev cov analogues muaj xws li tshuaj xws li "Aktrafan", "Biogulin", "Diafan". Nyob rau hauv tej rooj plaub, cov neeg mob noj cov tshuaj pom zoo "Protafan", "Humodar", "Pensulin". Tsis phem kuj xam insulins "puag" thiab cov "Verein". Nws yog to taub hais tias lub tshuaj hormones - loj cov tshuaj thiab siv lawv tus kheej los yog nyob rau hauv txhua rooj plaub tsis yooj yim sua. Tsuas yog ib tug kws kho mob yuav xaiv tus analogue, thiab los mus txiav txim cov tshuaj tsawg. Piv txwv li, muaj cov nyob rau hauv cov tshuaj muaj tsawg kawg yog ib tug additive nyob rau hauv ib co neeg mob yuav ua rau loj heev tsis haum teb mus txog anaphylactic poob siab.

Ntaub ntawv hais txog cov kev sis raug zoo nrog lwm yam tshuaj

Ua ntej txoj kev kho tas yuav mus qhia rau koj tus kws kho mob txog kev noj tshuaj. Synthetic insulin txiav txim no yog kho kom zoo los ntawm simultaneous thawj coj nrog sulfonamides, adrogenami thiab anabolic steroids, Mao inhibitors, nonsteroidal antiinflammatory tshuaj. Lub hypoglycemic nyhuv yog ntau pronounced nyob rau tom qab ntawm lub simultaneous siv ntawm "Isophane" tshuaj ketoconazole, cyclophosphamide, quinine, chloroquine, quinidine tshuaj uas muaj lithium. Los ntawm txoj kev, txoj kev kho yog tsis pom zoo kom haus dej haus cawv, raws li ethanol tej cov nyhuv ntawm cov khoom cua insulin.

Estrogens, qhov ncauj kontsratseptivy, glucagon, heparin, thyroid hormones tsis muaj zog cov nyhuv ntawm cov tshuaj. Yam muaj tseeb ntawm nicotine, tshuaj maj, morphine, tej diuretics (eg, thiazide thiab voj), tricyclic antidepressants.

Nyob rau hauv txhua rooj plaub nws yog tsim nyog los nkag siab hais tias tsis muaj ib tug kws kho mob txoj kev tso cai yuav pauv tsis tau cov tshuaj los yog lub sij hawm ntawm thawj coj ntawm cov kua dej los. Cov tsos ntawm puas thiab phiv tshuaj yuav tsum tau qhia mus rau lub mus kawm endocrinologist.