Los ntawm dab tsi pab "Hypothiazid". "Hypothiazid": phau ntawv no, xyuas, analogs

Niaj hnub no peb qhia rau koj tias los ntawm dab tsi pab "Hypothiazid"? Tsis tas li ntawd nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm yuav tsum tau muab cov lus qhia rau kev siv ntawm cov tshuaj, neeg xyuas, tus duab ntawm nws tso tawm, thiab lwm yam khoom.

Hauj lwm ntawm cov kev npaj, zoo, thiab muaj pes tsawg leeg ntawm ntim

Los ntawm dab tsi pab "Hypothiazid"? Ua ntej teb lo lus nug no, nws yog tsim nyog los qhia rau dab tsi daim ntawv tshuaj no mus rau lub tsev muag tshuaj.

"Hypothiazid" yog ua nyob rau hauv daim ntawv ntawm cov dawb ntsiav tshuaj (tej zaum yuav muaj ib tug grayish Hawj txawm). Lawv muaj ib tug yeej thiab tiaj tus zoo, muaj kev pheej hmoo rau ntawm ib sab thiab engraving "H" - mus rau lwm lub.

Lub active keeb ntawm cov tshuaj tshuaj hydrochlorothiazide. Tsis tas li ntawd nws muaj koom haum pab hais xws li magnesium stearate, lactose monohydrate, talc, gelatine thiab cov hmoov txhuv nplej pobkws.

Nyob rau hauv lub qhov muag ntawm lub tsev no yog nkag rau hauv sawv hlwv packs, uas yog fej nyob rau hauv cov duab los qhia thawv.

Cov tshuaj

Yuav ua li cas yog cov tshuaj "Hypothiazid"? Los ntawm dab tsi pab no tshuaj?

Raws li cov lus qhia, xam tau tias yog cov tshuaj yog ib tug diuretic. Nws thawj mechanism ntawm qhov kev txiav txim yog ib qho kev nce rau hauv diuresis los ntawm inhibition ntawm reabsorption ntawm sodium thiab chloride ions nyob rau hauv lub pib cheeb tsam ntawm lub raum tubules. Cov nyhuv no ua rau yus muaj zog feem ntawm cov tshuaj, sodium, thiab, raws li ib tug tsim nyog tau, dej.

Nws yuav tsum tau muab sau tseg tias, tom qab tau txais hais tias medicament tsub kom lub feem ntawm lwm yam electrolytes, thiab ntau yeej poov tshuaj thiab magnesium.

Nyob rau hauv siab kho koob tshuaj natriuretic thiab diuretic los ntawm cov tshuaj no yog cov tib.

Diuresis thiab natriuresis tshwm sim rau 120 feeb thiab mus txog nqi siab tshaj tom qab 4 teev.

Nws yuav tsum tau muab sau tseg tias medicament thiaj carbonic anhydrase kev ua si los ntawm kev ua cov feem ntawm bicarbonate ions. Txawm li cas los, qhov no ua rau ntawm cov tshuaj yog tsis muaj zog thiab tsis cuam tshuam rau pH ntawm cov zis.

Active muaj "gipotiazid" possesses antihypertensive zog. Peb tsis tau hais tias cov tshuaj nyob rau hauv kev saib xyuas twb tsis muaj ntxim rau cov ntshav siab.

Lub kinetics ntawm cov tshuaj

Seb tshuaj yog absorbed "Hypothiazid"? Cov lus qhia, cov khoom hauj lwm daim ntawv qhia tias hydrochlorothiazide yog tsis tau kiag li, tab sis nws yog heev sai absorbed ntawm lub digestive system. Cov nyhuv no tsawv rau 6-12 teev.

Thaum tau txais cov tshuaj lus nyob rau hauv ib tug ntau npaum ntawm 100 mg ntawm nws cov ncov concentration yog mus txog tom qab 2.5 teev nyob rau hauv ntshav.

Kev sib txuas lus nrog ntshav cov nqaijrog yog 40%.

Raws li cov kws txawj, hydrochlorothiazide yog tso tawm nrog rau mis mis nyuj thiab penetrates los ntawm lub placental barrier.

Feem ntawm lub cuab tam nqa los ntawm ob lub raum nyob rau 6 teev.

Medicament "Hypothiazid": dab tsi pab?

Qhov no tshuaj yog tshuaj rau:

• tiv thaiv lub tsim ntawm lub pob zeb nyob rau hauv lub mob txeeb zig nyob rau hauv cov tib neeg yooj yim rau lawv tus kab mob no (kom txo hypercalciuria);
• tawg (monotherapy los yog nyob rau hauv ua ke nrog nrog rau lwm cov antihypertensive yeeb siv tshuaj) ;
• tswj polyuria (mas nyob rau hauv nephrogenic mob ntshav qab zib insipidus);
• Edema syndrome txawv keeb kwm (premenstrual nro syndrome, nephrotic syndrome, raum tsis ua hauj lwm, mob xwm, mob glomerulonephritis, corticosteroid kev kho mob, txhaws lub plawv tsis ua hauj lwm ib tug mob xwm, portal hypertension).

Contraindications

Qhov tseeb ntawm yog dab tsi ua rau "Hypothiazid" peb hais saum toj no. Tsis tas li ntawd yuav tsum paub txog lub contraindications ntawm no lub cuab tam. Cov muaj xws li:

• Cov me nyuam nyob rau hauv peb lub xyoo ntawm lub hnub nyoog;
• raum tsis ua hauj lwm nyob rau hauv kev mob loj;
• anuria;
• siab tsis ua hauj lwm nyob rau hauv kev mob loj;
• Addison tus kab mob;
• mob ntshav qab zib unmanageable;
• refractory hypokalemia, hyponatremia, hypercalcemia;
• nce rhiab heev rau cov tshuaj, thiab derivative ntsiab ntawm lub sulfonamides.

Nrog huab ceev faj yuav tsum raug siv qhov cuab tam nyob rau hauv ischemic plawv tus kab mob, hypokalemia, daim siab mob npuas paug, hyponatremia, gout, hypercalcemia, daim ntawv thov ntawm mob glycosides, lactose intolerance, thiab nyob rau hauv cov neeg laus.

Tshuaj "Hypothiazid": cov lus qhia rau kev siv

Xyuas analogues xam tau tias yog tshuaj nthuav tawm ntawm lub kawg ntawm tsab xov xwm.

Ntsiav tshuaj yuav tsum tau noj tom qab ib tug noj mov. Lawv koob xaiv nyob rau hauv lub chav kawm ntawm kev kho mob, nyob rau ib tug neeg zus.

Initial dosing ntawm cov tshuaj rau cov neeg laus:

• premenstrual nro syndrome: cov tshuaj pib nrog qhov pib ntawm cov tsos mob ua ntej poj niam (nyob rau hauv ib tug npaum li ntawm 25 mg ib hnub ib zaug).
• Edematous syndrome ntawm ntau yam keeb kwm: 25-100 mg ib hnub ib zaug los yog ib zaug nyob rau hauv ob hnub. Nyob rau hauv loj heev zaum cov tshuaj kho 200 mg.
• Tawg: 25-50 mg ib hnub ib zaug. Tus kho nyhuv ntawm cov tshuaj manifested rau 4 hnub.
• Nephrogenic mob ntshav qab zib insipidus: 50-150 mg txhua txhua hnub (nyob rau hauv faib koob tshuaj).

Raws li rau cov me nyuam, rau lawv xav hais tias cov tshuaj yog tshuaj raws li nyob rau hauv ceeb thawj. Lub sij hawm ntau npaum ntawm 1-2 mg / kg.

phiv

Tam sim no, koj paub, los ntawm dab tsi pab "Hypothiazid". Thaum noj cov tshuaj no tej zaum yuav tsim nram qab no sab tshua:

• anorexia, qhov ncauj qhuav, nqaij tu-sauv, raws plab;
• mob ib ce, cem quav, qaug zog, cholecystitis, tsis muaj zog, cholestatic daj ntseg;
• nkees, pancreatitis, nqhis dej, sialadenitis;
• arrhythmia, aplastic anemia, vasculitis, thrombocytopenia, mob taub hau, leukopenia;
• kiv taub hau, hemolytic anemia, raum muaj nuj nqi ntshawv siab, agranulocytosis, thiab lwm tus neeg.

Analogs thiab kev xyuas txog cov tshuaj "Hypothiazid"

Xyuas ntawm "hydrochlorothiazide" tsab ntawv ceeb toom hais tias nws yog ib qho zoo thiab ceev ceev-kuj diuretic. Tau txais xws ntsiav tshuaj pub tsim ntawm lub pob zeb nyob rau hauv lub mob txeeb zig, lowers ntshav siab thiab eliminates lub o ntawm ntau yam keeb kwm.

Qhov tsis zoo ntawm qhov suav hais tias cov tshuaj nqa ib tug loj tus naj npawb ntawm cov nyom tshua.

Zoo li txhais tau tias ntawm cov tshuaj no yog: "hydrochlorothiazide", "Hydrochlorothiazide-CAP", "Dihlotiazid", "hydrochlorothiazide-Verte" thiab lwm tus neeg.