Pob Txha cov ntaub so ntswg: ntxwv nta thiab zog

Pob Txha cov ntaub so ntswg yog txawv kev txhua yam khoom ntawm lub txhawb ntaub uas yog tsim los ntawm cov pob txha hlwb thiab tshwj xeeb intermediate. Tus qauv muaj xws li ib nrab collagen fiber (pob txha matrix) thiab txawv inorganic tebchaw. Tsis tas li ntawd, cov pob txha cov ntaub so ntswg muaj lacunary-canalicular system muaj ib tug network ntawm me me lacunae thiab canaliculi thiab muab intraosseous metabolism.

Pob Txha lub hlwb yog peb hom: osteoclasts, osteoblasts thiab osteocytes. Osteoclasts - ib tug loj multinucleated hlwb ntawm monocytic keeb kwm, qhov luaj li cas ntawm cov uas tej zaum yuav mus txog 190 microns. Cov hlwb yog muab kev koom tes nyob rau hauv lub resorption (kev puas tsuaj) ntawm cov pob txha thiab pob txha mos. Nyob rau hauv physiological thiab reparative lwm cov pob txha resorption, osteoclasts nqa nws. Osteoclast kev ua si yog ncaj qha nyob rau ntawm tus nqi ntawm parathyroid lawm, lub zog synthesis ntawm cov uas yuav txais qhov ua kom ntawm osteoclast muaj nuj nqi, ua rau kev puas tsuaj ntawm tus pob txha.

Osteoblasts - tseem hluas polygonal lub voos xwmfab pob txha hlwb tshwm sim nyob rau hauv tus nto khaubncaws sab nraud povtseg ntawm cov pob txha thiab surrounded los ntawm ib tug nyias collagen microfibrils. Lub ntsiab muaj nuj nqi ntawm osteoblasts yog coj los ua ke extracellular matrix Cheebtsam - pob txha collagen thiab regulating mineralization.

Osteocytes thiab cov txheej txheem ntawm nyob rau hauv qhov khoob yog fusiform mnogootrostchatye mature pob txha hlwb, regulating metabolism intraosseous.

Nws muaj ob hom ntawm cov pob txha cov ntaub so ntswg: ntxhib-fibered thiab cov nplooj. Nyob rau hauv cov laus, ntxhib-fibered pob txha cov ntaub so ntswg nyob rau hauv cov pob qij txha ntawm lub pob txha taub hau thiab cov pob txha ntawm cov aav ntawm txuas rau tendons, muaj amorphous thiab disordered tuab bundles ntawm collagen fibers. Muaj pes tsawg leeg ntawm lamellar pob txha muaj xws li cov pob txha phiaj ib tug tuab ntawm 4-15 microns osteocytes, yooj yim tshuaj thiab nyias collagen fibers.

Pob Txha cov ntaub so ntswg, raws li zoo raws li lwm yam kabmob ntawm tus tib neeg lub cev yog raug mus rau ntau yam inflammations, thiab cov kab mob. Pathogens o tej zaum yuav tsum tau qhia rau hauv nws los ntawm cov hlab ntsha, piv txwv li. E. Lub hematogenous lawv, nyob rau hauv cov kev tshwm sim hais tias tus neeg mob muaj purulent hearth. O ntawm cov pob txha cov ntaub so ntswg hu ua osteomyelitis predisposing yam uas yuav ua tau beriberi, kev poob plig, qaug zog, cua txias thiab thiaj li nyob. Nyob ntawm seb cov kev siv thiab ceev ntawm osteomyelitis paub qhov txawv mob, mob thiab subacute ntaub ntawv ntawm tus kab mob.

Cov tshwm sim ntawm ib tug ntev inflammatory pob txha cov ntaub so ntswg yog vascular txhaws thiab cov neeg pluag kev (thrombosis). Yog li ntawd, deprived ntawm kev noj haus pob txha cov ntaub so ntswg pib mus ua txhaum down mertvet thiab, raws li ib tug yuav tau txais, yog necrosis (necrosis) thiab kev puas tsuaj ntawm tus pob txha cov ntaub so ntswg. Nyob rau hauv tas li ntawd, muaj yog ib tug tsis necrotic pob txha chaw thiab txoj kev poob ntawm kev sib txuas lus nrog cov noj qab nyob zoo pob txha ntaub so ntswg, tsim lub thiaj li hu ua sequesters.

Lub ntsiab yog vim li cas kev ua osteomyelitis (o ntawm cov pob txha ntaub so ntswg) yog pyogenic kab mob: streptococci, staphylococci thiab pneumococci, thiab hnyuv, typhoid Bacillus thiab lwm yam microbes. Ib tug ntau yam ntawm osteomyelitis xam tau tias yog inflammatory kab mob xws li kab mob ntsws, cov pob txha txhaum cai loj thiab pob txha.

Osteomyelitis kev kho mob yog los rhuav tshem tus kab mob nrog tshuaj tua kab mob, uas yog xaiv ib lub zuj zus nyob ntawm seb hom ntawm cov kab mob. Tshuaj tua kab mob yuav kav li ob lub hlis. Tus thawj hnub ntawm cov tshuaj yog npaum li cas nyob rau hauv cov ntsiav tshuaj daim ntawv, yog tias plaub hnub tsis muaj txoj kev txhim kho yog cai, cov tshuaj no yog muab intravenously los yog txuas ntxiv ncaj nraim mus rau hauv qhov chaw ntawm osteomyelitis.