Prednisolone: cov lus qhia rau kev siv, cov khoom pharmacological

Tso daim ntawv "Prednisolone" tshuaj: mos lam ntaub ntawv - tshuaj pleev.

Farmsvoystva

Prednisolone yog ib tug dehydrogenated analogue ntawm hydrocortisone. Antiallergic, antiinflammatory, antiexudative thiab antipruritic nyhuv thaum siv topically tshuaj pleev "prednisolone" qhia ua rau ib tug txo nyob rau hauv lub tsim, tso tawm thiab kev ua si ntawm o kev sib kho (kinin, ib tug histamine, lysosomal enzymes, prostaglandins). Tsis tas li ntawd inhibited cell tsiv teb tsaws rau inflammatory epicenter txo vasodilation thiab muaj zog vascular permeability uas tshwm sim nyob rau hauv o. Txo cov exudation yog vim lub vasoconstrictor kev txiav txim ntawm "Prednisolone" tshuaj. Phau ntawv qhia tias cov tshuaj yog ib qho immunosuppressive nyhuv los ntawm inhibiting qhov kev txiav txim ntawm lub antigen-antibody complex thiab accumulating ntawm cov phab ntsa hauv cov hlab ntsha thiab yog qhov ua rau ntawm kev tsis haum vasculitis. Cov tshuaj cheeb qhov uas cov kev txiav txim ntawm macrophages, cytokines, lub hom phiaj hlwb uas ua rau txoj kev loj hlob ntawm kev tsis haum cov tshuaj tiv thaiv hom kis dermatitis. Yog li sensitized T-lymphocytes thiab macrophages yuav tsis tau nkag mus rau lub hom phiaj hlwb.

tshuaj

Thaum daim ntawv thov ntawm tshuaj pleev "Prednisolone" absorbed thiab lub active tshuaj yog nyob rau hauv cov hlab ntsha. Nyob rau hauv cov ntshav ntshav prednisolone feem yog lwm yam kev rau albumin thiab transcortin. Biotransformation prednisolone tshwm sim los ntawm oxidation, mas nyob rau hauv lub siab, nyob qhov twg glucuronidation los yog sulfation tshwm sim oxidized cov ntaub ntawv. Nyob rau hauv daim ntawv ntawm cov metabolites tas nyob hauv cov zis thiab feces, ib feem - nyob rau hauv ib tug unmodified lub xeev. Prednisolone kis los ntawm tus placental barrier nyob rau hauv me me ntau, nws yuav pom nyob rau hauv lub mis mis nyuj ntawm cov poj niam.

Prednisolone: zaj lus tim khawv

Lub tshuaj no yog siv nyob rau hauv tus neeg mob ntawm:

- tsis haum thiab irritant hu dermatitis,

- eczema,

- atopic dermatitis,

- seborrheic dermatitis,

- psoriasis.

Prednisolone: kev qhia

Cov tshuaj pleev yog thov mus rau lub qhov txhab qhov chaw tusyees 1-3 lub sij hawm / hnub. Duration ntawm kev kho mob yog tshwm sim los ntawm qhov xwm ntawm tus kab mob no thiab feem ntau tsuas kav 8-14 hnub. Tshuaj pleev nyob rau hauv cov kev kho mob ntawm cov me nyuam ntev ntawm kev kho mob yuav tsum raug txo kom 3-7 hnub, txij li thaum tus me nyuam lub cev yog rhiab rau cov tshuaj "Prednisolone". Instruction xav tso tseg sov, kho thiab occlusive cov ntaub qhwv.

Nta ntawm daim ntawv thov

Lub caij ntawm kev kho mob nrog tshuaj pleev yuav tsum tsis txhob yuav ntau tshaj 14 hnub nyob rau hauv thiaj li yuav tiv thaiv kom txhob tau kev phiv los ntawm kev siv ntawm "Prednisolone" tshuaj. Instruction prescribes los kho xwb nyob rau hauv kev kho mob saib xyuas.

phiv

Feem ntau cov tshuaj yog zoo taus. Muaj tsawg tsawg zaus tshwj xeeb tshaj yog tom qab heev siv, tej zaum yuav ua rau khaus, kub nov ntawm nqaij tawv, erythema. Nyob rau hauv ib co neeg mob lub sab los thov tsa tes raws li folliculitis, hypertrichosis, perioral dermatitis, kev tsis haum tshuaj rau cov tshuaj Cheebtsam. Qhov saum toj no cov tsos mob tsis yuav tsum tau kev kho mob thiab sai sai tshem tawm ntawm lub txiav ntawm daim ntawv thov ntawm cov tshuaj. Nws yuav tsum tau nco ntsoov tias daim ntawv thov ntawm ib tug tshuaj pleev rau cov tawv nqaij thiab ntev-lub sij hawm siv (tshwj xeeb tshaj yog nyob rau hauv lub yeej ntawm loj cheeb tsam ntawm daim tawv nqaij) tej zaum yuav tshwm sim tshwm sim los ntawm ib tug mauj xwm.

Sib tshuam nrog lwm yam tshuaj

Prednisolone muaj cov cuab yeej los mus txhawb nqa anticoagulant nyhuv ntawm anticoagulants. Nws tsub kom tau los ntshav thaum noj salicylates. Nws tsub kom qhov yuav ntawm ntsha metabolism mob nrog concomitant thawj coj ntawm diuretics. Muaj yog ib tug loj hlob kev uas yuav toxicity thaum uas siv cov mob glycosides. Tsis hypoglycemic antidiabetic nyhuv thiab txo cov antibacterial kev ua ntawm rifampicin. Tsis pom zoo rau siv nyob rau hauv ua ke nrog antacids.

Contraindications

Kev Kho Mob "Prednisolone" tshuaj pleev qhia yog txwv tsis pub nyob rau hauv:

- meem kev txhawj xeeb;

- kab mob, kab mob, fungal daim tawv nqaij qhov chaw mob;

- kab mob ntsws, syphilis, daim tawv nqaij hlav, cev xeeb tub, cov pob txuv thiab liab pob txuv.

overdose

Mob ntawm overdose yog tsis paub hais tias.

cia tej yam kev mob

Khaws cia rau hauv daim ntawv B, nyob 5-15ºS. Txee lub neej - 2 xyoo. Thaum lub sij hawm ntawm lub txee lub neej tsis tau siv.

tej yam kev mob ntawm mov

Tshuaj.