"Teopeka" (300 mg): cov lus qhia rau kev siv, indications, chaw tsim tshuaj paus

Cov neeg uas muaj mob hawb pob, paub yuav ua li cas ib qho tseem ceeb lub sij hawm los pab nrog bronchospasm. Tej zaum qhov tseeb txiav txim nyob rau hauv no nyuaj qhov teeb meem no thiaj yuav cawm tau lub neej. Ib tug tseem ceeb luag hauj lwm nyob rau hauv tau txais los ntawm cov neeg mob ntsws ua si bronchodilators.

Hauj lwm ntawm cov kev npaj

"Teopeka" (300 mg), cov lus qhia rau kev siv uas yog qhia nyob rau hauv daim ntawv no yog ib tug dawb cov ntsiav tshuaj ploskotsilindricheskoy yeej zoo lawm, uas yog tau ntim rau hauv ntim contour. Lub ntsiab active ingredient ntawm cov tshuaj yog theophylline. Nws concentration nyob rau hauv ib ntsiav tshuaj ntawm qhov kev npaj ntawm daim ntawv no yog 300 mg.

Yuav ua li cas li no tshuaj?

Los ntawm nws pharmacological kev txiav txim ntawm theophylline, uas yog ib tug derivative ntawm purine, muaj ib tug inhibiting ntxim rau cov phosphodiesterase. Lub active ingredient ntawm cov tshuaj blocks cov kev purine receptors, nkoos Camp txuam nyob rau hauv cov ntaub so ntswg depots, lowers tus muaj peev xwm ntawm tus nqaij rau daim ntawv cog lus, kom txhob muaj tus nqi ntawm cov dawb calcium ions, uas mus los ntawm cell week.

Cim cov lus hais vasodilating nyhuv txais tos "teopeka" npaj (300 mg). Cov lus qhia rau kev siv qhia txog cov cuab yeej raws li ib tug cawv rau cov peripheral cov hlab ntsha. Theophylline tsub kom ntshav khiav los ntawm cov raum system, yeej txhawb so ntawm bronchial tus nqaij thiab cov hlab ntsha. Tsis tas li ntawd, qhov kev txiav txim ntawm lub active tivthaiv yog yus li me me diuretic. Theophylline tiv thaiv qhov uas qhia tawm ntawm tshuaj nyob rau hauv thiab tawm, provoking ib tug tsis haum teb raws li tsub kom tus stability ntawm mast cell week. Yog hais tias ib tug neeg mob hypokalemia active tshuaj intensifies cua.

Theophylline pab normalize cov hauj lwm ntawm kev ua pa, activating coj chaw nyob rau hauv lub hlwb, uas ua nyob rau hauv ib tug zoo dua cov ntshav oxygen saturation, nws decreases concentration ntawm cov pa roj carbon dioxide. Tshuaj "teopeka" nkoos diaphragm, yuav ua rau nws txiav. Nws kuj yuav tsub kom tus nqi ntawm cov qhov taw qhia ntawm mucociliary clearance ua si intensifies pa thiab intercostal leeg.

Theophylline ua rau ntshav mikrotsirkullyatsiyu thiaj thrombus tsim, kev tshaj suppresses thiab eliminates aggregation ntawm platelet hlwb. tshuaj kuj pab cov ndlwg ntawm cov ntshav zoo, tsub kom kuj mus deforming erythrocytes yam.

"Teopeka" (300 mg), li no kom txhob muaj tag nrho cov siab nyob rau hauv lub ntsig txog kev, thiab kuj thiaj li tsis kam nyob rau hauv lub pulmonary leeg tshav system. Raws li ib tug tshwm sim, lub suab nrov ntawm daim tawv nqaij integuments, raum thiab lub hlwb lawm. Raws li ib tug tshwm sim uas tau txais theophylline cim stimulation ntawm coronary ntshav txaus, muaj mob si, kev nce ntawm myocardial stunning hlwb xav tau kev pab oxygen, quickens tus mem tes, lub dag lub zog ntawm lub plawv contractions nce.

Tshuaj thiab pharmacodynamics ntawm cov tshuaj

Tom qab tus neeg mob coj cov ntsiav tshuaj nrog theophylline, lub yam khoom uas yog kiag li absorbed los ntawm cov hnyuv ib ntsuj av. Khoom noj khoom haus haus muaj ib cov nyhuv rau tus nqi ntawm haum ntawm cov tshuaj, tab sis cov neeg kawm ntawv ntawm haum thiab clearance tseem unchanged. Txij li thaum ntshav protein uake 40% ntawm cov active tshuaj. Theophylline metabolism tshwm sim nyob rau hauv lub siab los ntawm cytochrome P450.

Feem ntawm metabolites ua nyob rau hauv active daim ntawv ntawm ob lub raum, tab sis 10% ntawm cov tshuaj no yog tshem tawm nyob rau hauv nws thawj daim ntawv. Ib txhia yam muaj ib tug tseem ceeb ntxim rau cov metabolism ntawm theophylline. Haus luam yeeb, noj tej yam tshuaj, kev noj haus tsis tau, comorbidities, hnub nyoog, muaj peev xwm mus ua kev kho me ntsis rau cov kev pauv ntawm lub active tshuaj nyob rau hauv tib neeg lub cev. Txo qhov clearance ntawm theophylline yog cai nyob rau hauv lub ntsws edema, daim siab tus kab mob, COPD, thiab nyob rau hauv lub plawv tsis ua hauj lwm.

Leej twg yuav zoo siab txais tos no lub cuab tam?

Muaj tej yam tej yam kev mob rau cov uas ib tug "teopeka" (300 mg). Cov lus qhia rau kev siv piav qhia txog nram qab no cov kab mob:

• obstructive ntsws nyob rau hauv mob daim ntawv;
• pw tsaug zog apnea;
• mob hawb pob;
• mob hawb pob;
• pulmonary tawg;
• pulmonary lub plawv.

Tsis tas li ntawd, cov tshuaj "teopeka" zoo tswv yim uas yuav tau mus thov nyob rau hauv nrog lwm yam tshuaj nyob rau hauv cov kev kho mob ntawm lub raum edema xwm. Cov neeg mob nco ntsoov lub high efficiency ntawm lub cuab tam thiab nws ibqho rau cov kev kho mob ntawm cov kab mob ntawm lub pa system.

Contraindications

Txawm li cas los, cov tshuaj no yuav siv tau tsis txhua leej txhua tus, vim hais tias ntawm lub xub ntiag ntawm ib tug xov tooj ntawm cov lus ceeb toom los ntawm cov nyiaj. "Teopeka" contraindications yog raws li nram no:

• hemorrhagic stroke hom;
• qaug dab peg;
• los ntshav los ntawm tus mob huam nyob rau hauv keeb kwm;
• rwj tsim nyob rau hauv lub digestive kabmob;
• tachycardia siab severities;
• tawg los yog hypotension;
• npau taws me ntsis;
• gastritis, nrog los ntawm high acidity;
• Cov me nyuam mus txog lub hnub nyoog 12 xyoo.

Nyob rau hauv lub xub ntiag ntawm tsawg kawg yog ib tug ntawm cov syndromes los yog tej yam kev mob ntawm cov tshuaj theophylline yuav tsum tso tseg

phiv

Muaj yog ib tug loj heev pab pawg neeg ntawm sab-los los ntawm kev noj "teopeka" npaj (300 mg). Cov lus qhia rau kev siv ntawm lawv shares rau lub mauj ces:

• mob ntawm poob siab system: mob taub hau, kiv taub hau, pw tsaug zog ua cuam tshuam, nyob tsis tswm, nce ntxhov siab vim thiab txob taus, tshee;
• kawg ntawm lub plawv thiab cov hlab ntsha: tachycardia, arrhythmia, hypotension, nce zaus ntawm angina sib cem, cuav angina;
• ua txhaum hnyuv qub hauj lwm: xeev siab, gastralgia, ntuav, kub siab, reflux, exacerbation ulcers, raws plab, tsis qab los noj mov;
• ces kev tsis haum tshuaj: daim tawv nqaij sawv pob, kub taub hau, khaus;
• cov lwm cov nyom txheej xwm ntawm kev noj cov tshuaj tau sau tseg: tachypnea, albuminuria, nce diuresis, mob nyob rau hauv lub kaus siab, hematuria, kais, nce tawm hws, gipoglekemiya.

Feem ntau, tus kho lus ntawm cov tshuaj kom txo tau cov kev phiv yog txo los yog tso ntawv tseg tsis zoo rau nws.

Yuav ua li cas mus noj cov tshuaj?

Txhais tau hais tias los ntawm bronchitis, xws li "teopeka" raug xwb los ntawm lub mus kawm tus kws kho mob thiab lawv ntau npaum xaiv rau ib tug neeg zus. Qhov nruab nrab txhua hnub nome sib npaug 400 mg theophylline. Yog hais tias ib tug neeg mob yog cov tshuaj zoo, ces tom qab 2-3 hnub los ntawm tus thawj koob tshuaj ntawm cov tshuaj, lub volume nce los ntawm 25% thiab ntxiv los ntawm tus kws kho mob pom zoo.

Thaum tau txais txhais tau tias los ntawm ntsws "teopeka" nyob rau hauv ib tug txhua txhua hnub koob tshuaj tsawg tshaj li 900 mg theophylline cov ntsiab lus tswj yog tsis tsim nyog nyob rau hauv tus neeg mob cov ntshav. Yog hais tias koj khij lub manifestation ntawm intoxication, ceev yuav tsum tau tsim kom muaj cov tswj lub theem ntawm concentration ntawm lub ntsiab active khoom sib ua zaub mov nyob rau hauv cov ntshav. Qhov zoo tshaj plaws xam tau tias yog ntsuas 10-20 micrograms per ml. Yog hais tias lub theophylline cov ntsiab lus ntawm tus neeg mob cov ntshav siab dua li ib txwm, lub cai kev loj hlob tsis zoo tshua. Nyob rau hauv cov ntaub ntawv no nws yog tsim nyog los txo cov tshuaj ntawm cov tshuaj, thiab ib tug kho nyhuv yuav tsis muaj zog.

Yeej yuav muaj ib tug overdose?

Bronchodilators xws li "teopeka" tej zaum yuav ua rau kom mob loj heev ntawm lub cev nyob rau hauv cov kev tshwm sim ntawm overdose. Thaum zoo sib phim hnub tus nqi ntawm lub tau txais txhais tau tias cov nram qab no cov tsos mob tej zaum yuav tshwm sim:

• tsis qab los noj mov;
• insomnia;
• raws plab;
• ventricular arrhythmias zoo lawm;
• tachycardia;
• los ntshav ntawm lub digestive system;
• tachypnea;
• co;
• ntxhov siab vim;
• yaug kais dej ntawm daim tawv nqaij ;
• nce excitability;
• ntshai ntawm lub teeb;
• ntuav ntshav.

Nws kuj los muaj kev mob loj heev rau lom, uas manifests nws tus kheej nyob rau hauv cov nram no cov tsos mob:

• tshwm sim ntawm epileptic qaug dab peg;
• hypokalemia;
• raum tsis ua hauj lwm, myoglobinuria;
• hypotension;
• tsis meej pem;
• hyperglycemia;
• metabolic acidosis.

Yuav ua li cas nyob rau hauv cov ntaub ntawv no?

Yog hais tias muaj yog pov thawj ntawm tej yam tshwm sim los yog lub sijhawm twg los ntawm lawv yuav tsum ua ib tug pais plab lavage, muab tus neeg mob chelators, cov tshuaj ntaus cev, tshuaj, raws li zoo raws li npaj diuresis plasmasorption, hemodialysis thiab hemosorption. Yog hais tias tus neeg mob yog muaj qaug dab peg, ces nws yog pom zoo kom paub cov pa txoj kev kho thiab tso dej "Diazepam" uas yuav pab tau kom zoo ntes tus qaug dab peg. Nyob rau hauv cov ntaub ntawv ntawm cov lus hais xeev siab thiab ntuav yuav tsum taw tso dej "Ondansetron" tshuaj thiab "Metaklopromida".

Yuav ua li cas cov tshuaj yuav tsis tau ua ke "teopeka"?

Bronchodilators xws li "teopeka 'yuav tsum tsis txhob coj ua ke nrog ib tug macrolide-tshuaj tua kab mob" Allopurinol "," cimetidine "," Lincomycin "," isoprenaline ", raws li zoo raws li qhov ncauj contraceptives vim hais tias cov tshuaj yuav pab txo cov clearance ntawm theophylline.

Nws tsis pom zoo kom muab kom tsawg ntawm cov beta-blockers, tshwj xeeb yog cov uas tsis-xim, nrog rau cov tshuaj "teopeka", los ntawm uas tej zaum yuav tsim bronchial constriction thiab cov txo cov hlab ntsws qhib nyhuv ntawm theophylline.

Yog hais tias "teopeka" thov ua ke nrog "Furosemide" caffeine thiab lwm yam uas kov beta-2 adrenergic receptors, cov kev ua ntawm nws cov thawj tivthaiv yog ho muaj zog. Yog hais tias tag nrho nrog rau theophylline "Aminoglutitemidom", tus thawj khoom pib los mus tas los rau ntawm lub cev thiab nws cov efficiency rau.

"Acyclovir" yog peev xwm ua rau lub concentration ntawm lub ntsiab active khoom sib ua zaub mov "teopeka" thiab tsub kom qhov tsis zoo los ntawm nws txais tos. Zoo li cov phenomena muaj cai thaum co-xeem nrog theophylline tshuaj "Dialteazem", "Felodipine" "Verapamil", "Nefedipin". Cov tshuaj no tsis txhob hloov cov hlab ntsws qhib nyhuv, txawm li cas los, tus neeg mob tej zaum yuav muaj cov tsos mob ntawm kev phiv tshuaj los yog overdose.

Substance "Disulfiram" muaj peev xwm zuj zus theophylline ntshav rau ib qho tseem ceeb ntsuas tej tshuaj lom lesion. "Propranolol", rau hauv sib piv, thiaj li "teopeka" clearance ntawm lub active tshuaj. Concentration ntawm theophylline yog nce los ntawm somestnom nws txais tos nrog "enoxacin" thiab fluoroquinolones. Thaum theophylline txoj kev kho txo lub efficiency ntawm lithium ntsev.

Yog hais tias tag nrho kev kho mob nrog "pentobarbital", "Carbamazepine", "Isoniazid", "rifamycins", "sulfinpyrazone" muaj clearance "teopeka" thiab thiaj li nws cov hauj lwm zoo. Thaum concomitantly nrog theophylline "phenytoin" muaj kev sib nrig sib inhibition ntawm active kev tivthaiv nyob rau hauv tus neeg mob cov ntshav.

Cov txheej txheem no yog tshwj xeeb yog ib qho tseem ceeb, uas raug nqi ntau lawv yog fraught nrog noj qab haus huv tej teeb meem. Yog li ntawd, ua ntej yuav noj "teopeka", nyeem cov lus qhia kom zoo zoo. Thiab yog hais tias koj raug kho rau ib yam ntawm cov saum toj no cov tshuaj, nrog koj tus kws kho mob.

Yuav ua li cas mus yuav cov tshuaj thiab yuav ua li cas cov tshuaj yog tsim nyog?

Nyob rau hauv view ntawm lub loj contraindications thiab tshwm sim los ntawm cov tshuaj no, "teopeka" tso tawm nyob rau hauv pharmacies xwb los tshuaj.

Tshuaj "teopeka" tus nqe yog qhov nruab nrab nyob rau hauv Russia yog 160 rubles, nyob rau hauv cov chaw muag tshuaj los ntawm ntau yam manufacturers. Ib hom - tus kho rau "Borschagovsky CPP SPC" Ukrainian kws tuam txhab uas muag. Nws nqi yog 155 rubles. Lavxias teb sab ntau lawm ntawm "teopeka" yeeb tshuaj, 300 mg yog nqa tawm nyob rau qhauj ntawm JSC "Kws ua lag ua luam" thiab "Valens". cov tshuaj raug nqi 290 rubles thiab 190 rubles feem.

Nyob rau hauv dav dav, lub tshuaj "teopeka", tus nqi yog tau, xam tau tias yog pheej yig tshuaj rau ntau ntawm peb cov pej xeem. Nyob rau hauv kev sib piv nrog European counterparts qhov cuab tam yog ntau pheej yig dua. Lavxias teb sab ntau lawm ntawm "teopeka" cov tshuaj ua rau nws pheej yig.

Kom ceev faj txog thaum noj tshuaj

Thaum tau txais "teopeka" tshuaj, xyuas uas yog zoo, yuav tsum xyuam xim rau cov lus qhia nram qab. Yog hais tias tus neeg mob muaj mob hlab ntsha los yog mob insufficiency, atherosclerosis, cardiomyopathy, hnyuv rwj, daim siab tus kab mob, prostate cancer, oesophageal reflux, cev xeeb tub, hypothyroidism los yog nce propensity rau qaug dab peg, cov tshuaj theophylline yuav tsum tau noj nrog ceev faj.

Cov me nyuam nyob rau hauv 12 lub xyoos ntawm hnub nyoog thiab cov laus cov neeg mob "teopeka" tsa tsis tshua.

Tej zaum qhov kev siv ntawm lub qhov quav ntaub ntawv ntawm qhov kev siv yeeb tshuaj, tab sis lawv yuav tsum tau siv cautiously nyob rau hauv pathologies ntawm lub qhov quav thiab raws plab syndrome. Cov neeg mob uas tiv kev haus luam yeeb taw tes txos nyhuv ntawm kev kho mob "teopeka".

Xam tias yog inadmissible ob leeg kho mob theophylline thiab xanthine derivatives. Yog hais tias tus neeg mob yog cov neeg laus tau qhia concomitant cov kab mob, kab mob, daim siab mob, lub plawv thiab cov hlab ntsha, tus kws kho mob yog tsim nyog los kho koob tshuaj ntawm cov tshuaj.

Kuv nqa ib tug yeeb tshuaj rau cev xeeb tub cov poj niam?

Ib tug cev xeeb tub poj niam lub medicament yog qhia rau lub xub ntiag mob indications vim theophylline yog tau txeem lub tsho me nyuam. Yog hais tias txais tos "teopeka" qhia tau hais tias laus niam, lub lactation yuav tsum tau txiav.

Phau ntawv no yog ib tug yooj yim to taub version ntawm lub teb qhia, uas yog txuas mus rau yeeb tshuaj "teopeka". Nws yuav tsum tau nyeem kom zoo zoo ua ntej yuav siv nws. Yog hais tias muaj yog ib yam dab tsi koj yog tsis meej pem los yog nyob rau hauv tsis ntseeg, nrog koj tus kws kho mob.