Yaig ntawm lub plab: etiology thiab pathogenesis

Yaig ntawm lub plab - ib tug ncaj ntau tus kab mob, yog tsiag ntawv los ntawm tsim ntawm erosions rau ntawm qhov chaw ntawm lub qog ua kua membrane ntawm lub plab. Cov tsis xws luag yuav tshwm sim vim hais tias cov ces dag necrosis. Nyob rau hauv lawv kho connective caws pliav yuav tsis ua. Yaig ntawm lub plab - yog ib tug nyob ntawm nosological lub sij hawm uas combines recurrent mob puas dab nyob rau hauv lub pais plab mucosa. Tej zaum nws manifests nws tus kheej raws li ib tug cov tsos mob ntawm gastritis. Yog li ntawd, nyob rau hauv cov ntawv nyeem feem ntau tus kab mob no yog hu ua erosive gastritis.

Lub ntsiab ua rau ntawm tus kab mob yog huab tej yam uas yog lossi kuj nyob rau hauv tib neeg lub cev. Cov kev nyuaj siab yam (kub nyhiab, frostbite, kev raug mob, kev poob siab, polytrauma) ua ib tug ua txhaum ntawm neurohumoral mechanisms ntawm kev cai ntawm ntau lub nruab nrog, tshwj xeeb yog cov khoom noj khoom haus thiab secretory zog ntawm lub plab thiab cov hnyuv, txo tus kuj muaj tus kab mob. Muaj kuj yog ib tug kev tshuaj ntsuam genetic predisposition rau tus kab mob. Lub yaig ntawm lub plab kuj tshwm sim nyob rau hauv lub siv tshuaj (nitrofurans, corticosteroids, ethacrynic acid, veroshpiron, tolbutamide), dej caw, raws li zoo raws li cov kab mob ntawm lub endocrine system (mob ntshav qab zib, hyperparathyroidism).

Muaj coob tus ntseeg hais tias cov erosive gastritis tshwm sim los ntawm lub pathogenic kev txiav txim ntawm Campylobacter (Helicobacter pylori) nyob rau hauv tib neeg lub cev. Tseeb pom tau hais tias 95% ntawm cov neeg uas muaj duodenal ulcers raug kis kab mob nrog raws nraim qhov no zoo ntawm Campylobacter, tab sis cov neeg mob uas xws ulcers nyiaj rau xwb 1-6% ntawm tag nrho cov neeg uas muaj tus kab pathogen.

Yaig ntawm lub plab: pathogenesis (kab mob kev vam meej)

Nyob rau hauv tus ntawm kev nyuaj siab yam nyob rau hauv lub cev muaj complex thiab inter-txog biochemical dab, uas yog nrog neural thiab humoral mechanisms ntawm kev cai ntawm lub zog ntawm tag nrho cov lub cev, tshwj xeeb tshaj yog lub plab thiab cov hnyuv. Nce secretion ntawm adrenal cortex cov tshuaj hormones thiab histamine, uas txhim khu lub tso pa tawm ntawm pais plab kua txiv nrog ib qho kev nce nyob rau hauv kev ua si ntawm pepsin thiab nws cov ntsiab lus ntawm free hydrochloric acid. Ib txhij poob viscosity ntawm hnoos qeev secretion thiab uas thiaj li tiv thaiv mucosal muaj nuj nqi. Tsis tas li ntawd, muaj spasmodic contraction ntawm cov leeg ntawm lub plab thiab cov hnyuv, nce capillary permeability, ntaub so ntswg trophism ntxhov, uas ua rau yus tom qab rau inflammatory tshua, tsim ntawm erosions thiab ulcers ntawm lub pais plab mucosa. Nws yuav tau menyuam thiab tam sim ntawd ua rau ntawm cov teeb meem tej yam tshuaj lom mus rau lub mucosa. Yog li, nyob rau hauv lub pathogenesis ntawm pais plab yaig yog ib tug tseem ceeb ntawm lub tsis sib xws ntawm cov mucosal barrier muaj nuj nqi thiab lub tawg muaj peev xwm ntawm pais plab los yog plab hnyuv txheem. Muab lub xov tooj ntawm cov hlab ntsha nyob rau hauv lub cheeb tsam tsim los ntshav rwj. Nyob rau hauv no kab mob tsim ruaj khov haumxeeb plab mob, cov hnyuv, lub siab, pancreas thiab lwm yam kabmob thiab tshuab.

Ntau zaus (30-90%) nyob rau hauv cov tub ntxhais cov neeg muaj tus mob no tsis muaj ib yam tshwm sim. Tej zaum manifested kub siab, acid regurgitation, tsis tshua muaj tej zaum yuav mob nyob rau hauv lub plab. Mob erosive gastritis manifests uas raug soj ntsuam tej yam tshwm sim. Hais txog 80% ntawm cov neeg mob tsis txaus siab ntawm kub siab, belching, mob nyob rau hauv txoj cai qaum quadrant, tsam plab, raws plab thiab cem quav.

Cov neeg uas yog cov kws kho mob thiaj paub hais tias erosive gastritis, koj yuav tsum ua raws li ib tug khoom noj aimed ntawm txo pais plab ua si. Mus cuag lub hom phiaj no koj yuav tsum noj txoj cai. Ua ntej ntawm tag nrho cov, noj cov zaub mov rau pais plab yaig yuav tsis kam ntawm ntxhib fiber cov zaub mov uas yog nplua nuj nyob rau hauv cellulose (qos liab, stringy nqaij, turnips, bran mov, thiab lwm yam). Koj tsis tau noj kib zaub mov. Nws yuav tsum tsis txhob haus cawv, carbonated dej, citrus, kas fes, xim av mov, raws li tau zoo raws li txias thiab zaub mov kub.