Allopurinol, qhia rau tus hais txog, ntau npaum, tshwm sim thiab contraindications

"Allopurinol", cov kev qhia ntawv hais tawm nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj ntawm 100 mg. Nws yog hais txog ib tug yeeb tshuaj tshuaj protivopodagricakih txhais tau tias cheeb qhov uas cov synthesis ntawm uric acid. Raws li cov qauv "allopurinol" nws yog ib qho analog ntawm hypoxanthine, inhibitory loj enzyme uas koom nyob rau hauv lub tsim ntawm uric acid. Cov tshuaj "allopurinol" xyuas paub meej tias nws muaj feem xyuam rau lub xaus ntawm uric acid ntsev, nyob rau kev txiav ntawm lawv txoj kev kawm nyob rau hauv cov ntaub so ntswg ntawm lub cev thiab nyob rau hauv lub ob lub raum.

"Allopurinol" qhia rau tus zaj lus tim khawv

Cov tshuaj no yog tshuaj:
rau kev tiv thaiv, kev kho gout thiab hyperuricemia (xws li nyuab raum tsis ua hauj lwm) mob nephrolithiasis ,, urate nephropathy;
uas muaj calcium oxalate raum pob zeb nyob rau hauv ua ke nrog nrog hyperuricosuria;
ntawm kom urate theem, tsim raws li ib tug tshwm sim ntawm enzymatic mob;
rau kev tiv thaiv ntawm mob nephropathy thaum lub sij hawm cytostatic, tawg kev kho mob ntawm lub qog thiab leukemia;
thaum kho mob starvation.

"Allopurinol" qhia rau tus dosing

Tus kws kho mob teev cov koob tshuaj ntawm cov tshuaj nyob rau hauv ib tug neeg lub hauv paus nyob rau hauv lub
urate theem kuaj nyob rau hauv cov ntshav thiab nyob rau hauv cov zis, raws li zoo raws li nyob rau hauv lub concentration ntawm uric acid. Cov neeg laus taw 100 mg "Allopurinol" mus txog 900 mg ib hnub twg. Lub hnub koob tshuaj yuav tsum tau faib rau hauv 2-4 koob tshuaj. Cov ntsiav tshuaj yuav tsum tau noj tom qab noj mov.
Cov me nyuam nyob rau hauv lub hnub nyoog ntawm 15 txhua txhua hnub koob tshuaj xam nrog cov neeg raws li cov mis: 10-20 mg ib 1 kg lub cev hnyav ntawm ib tug me nyuam los yog muab 100 mg "Allopurinol" 400 mg.

Qhov siab tshaj plaws tshuaj rau cov neeg mob uas tsis hnov raum muaj nuj nqi yog 100 mg. Tus kws kho mob tej zaum yuav ua rau kom cov tshuaj yog hais tias tus keeb kwm yav dhau ntawm cov kev kho mob tseem unchanged theem siab ntawm urate pom nyob rau hauv cov ntshav thiab zis.

"Allopurinol" daim ntawv qhia rau sab los

Nyob rau hauv tsawg zaus, peb cai irregularities nyob rau hauv cov hlab plawv system, uas manifested tawg, bradycardia.
Tau irregularities nyob rau hauv lub digestive system uas yog qhia:
xeev siab, ntuav, raws plab, nraum nce nyob rau hauv transaminases cai nyob rau hauv lub ntshiab;
kab mob siab, siab kawg;
stomatitis (nyob rau hauv ib tug neeg cov neeg mob);
steatorrhea.

Nyob rau hauv cais tus neeg mob "Allopurinol" tshuaj tau tshwm sim los mob nyob rau hauv lub paj hlwb, uas muaj qhia:
tsis muaj zog, qaug zog, mob taub hau, kiv taub hau;
ataxia, tsaug zog, kev nyuaj siab;
coma, paresis, paresthesia;
tu-sauv, neuropathy;
nrig txog kev pom kev tsis taus; cataracts;
kev hloov nyob rau hauv cov qauv ntawm cov optic papilla;
dysgeusia.
Heev tsis tshua cai irregularities nyob rau hauv lub hematopoietic system uas yog manifested los ntawm thrombocytopenia, agranulocytosis thiab aplastic anemia, leukopenia (uas yuav muaj pab pawg neeg no muaj xws li cov neeg mob uas tau poob lub raum muaj nuj nqi).

Tau irregularities nyob rau hauv lub urinary system, uas tsis tshua muaj interstitial nephritis; nyob rau hauv ib tug neeg cov neeg mob - edema, uremia, hematuria.

Teeb nyob rau hauv endocrine system tshwm sim nyob rau hauv tsawg zaus, ntxiv lawm tshob, impotence, gynecomastia, mob ntshav qab zib.
Metabolic mob manifested nyob rau hauv ib tug ob peb tus neeg mob hyperlipidemia.
Cov kev tsis haum los yog dermatological phiv tshua.

"Allopurinol" qhia rau tus contraindications

Nws yog tsis yooj yim sua rau muab ib tug yeeb tshuaj:
nyob rau hauv mob ntawm lub siab, raum;
Cev xeeb tub thiab lactation;
nyob rau hauv cov ntaub ntawv ntawm npau taws me ntsis mus rau lub "Allopurinol".

Nyob rau hauv soj ntsuam xyaum, cov me nyuam hauv qab no 12 xyoo ntawm lub hnub nyoog, "Allopurinol" tshuaj tsuas yog rau cov kev kho mob ntawm phem hlav, nyob rau hauv leukemia, thaum enzyme mob, xws li Lesch-Nihena syndrome.