Antimicrobial TSifran. Tshuaj pab

Tshuaj "TSifran" yog ib qho antimicrobial neeg sawv cev nrog ib tug broad spectrum ntawm kev txiav txim thiab belongs rau lub pharmacological pab pawg neeg ntawm fluoroquinolones. Active Cheebtsam ntawm cov tshuaj yog ciprofloxacin thiab tinidazole. Vim tsuj ntawm DNA gyrase thiab kab mob DNA synthesis inhibition, cov active tshuaj yog heev kom nquag plias tshaj gram-tsis zoo microorganisms.

Nyob rau hauv kev, cov kev ua ntawm lub bactericidal kev txiav txim ntawm cov kev npaj "TSifran" phau ntawv qhia sau ntawv nrog kev hwm rau cov kab mob: Neisseriagonorrhoeae, Neisseriameningitidis, Haemophilusinfluenzae, Pseudomonasaeruginosa, Salmonellaspp, Escherichiacoli thiab lwm yam kab mob kab mob los ua thiab tsis ua penicillinase, raws li zoo raws li methicillin-resistant lim thiab Enterococcusspp, Chlamydiaspp, Mycobacteriumspp, Legionellaspp ... hom.

Pharmacological kev txiav txim ntawm bactericidal medicament sab spectrum "TSifran" cov lus qhia rau kev siv yog raws li nram no: "Lub cuab tam yog npaj rau cov kev kho mob ntawm cov kab pathologies zoo nyob rau hauv cov kev kho mob ntawm inflammatory dab - mixed kab mob provoked los ntawm cov kev ua ntawm aerobic thiab co kab mob thiab protozoa.".

tshuaj

Lub active cov khoom xyaw ntawm cov tshuaj "TSifran" cov lus qhia rau kev siv hais txog mas tau tshaj. Thiab ciprofloxacin thiab tinidazole muaj zoo haum nyob rau hauv txoj hnyuv ib ntsuj av.

Xav txhua lub active cov khoom xyaw ntawm cov tshuaj, nws yuav tsum tau muab sau tseg hais tias ciprofloxacin muaj txog 70% bioavailability. Nws haum yog tub ceevxwm dog dig, thaum lub sij hawm siv ib tug khoom noj khoom haus. Qhov no tshuaj muaj zoo permeability rau hauv ntaub so ntswg thiab kua nruab nrog cev, xws li cov pob txha, cov nqaij leeg, cov rog, thiab cov pob txha mos cov ntaub so ntswg. Nws penetrates mus rau hauv lub nruab nrog urinary system, xws li nyob rau hauv ib lub cev xws li cov prostate. Nws yog ib tug tsis pub leejtwg paub nws qhia ib tug siab concentration cov ntsiab lus kiprofloksatsina, raws li, tseeb, thiab nyob rau hauv cov phev, cov qaub ncaug, cov kua tsib, qog kua, hnoos qeev.

Tinidazole txawv tsis bioavailability. Qhov no feem kuj ntog sai thaum muaj kev kub ntau nyob rau hauv cov ntaub so ntswg ntawm tib neeg lub cev nruab nrab lub kua penetrates, nyob rau hauv kev nyob rau hauv hlwb txha nqaj qaum kua, uas yog feeb meej nyob rau hauv tib yam li nyob rau hauv cov ntshav theem. Hais txog ib tug peb lub hlis twg ntawm tus nqi ntawm cov noj tshuaj tas nyob hauv cov zis unchanged, hais txog 10% yog tso tawm nyob rau hauv daim ntawv ntawm cov metabolites, heev me me feem ntawm cov tivthaiv yoojyim lub cev nyob rau hauv lub faeces.

Indications rau tshuaj "TSifran" cov lus qhia rau kev siv yog hais txog mus rau lub mixed kev kho mob ntawm cov kab dab. Ntawm cov ntau tej pathologies, rau cov kev kho mob ntawm cov tshuaj nyob rau hauv kev saib xyuas uas yog siv cov nram no cov kab mob:

• mob osteomyelitis ;

• intra-kab inflammatory dab;

• amoebic dysentery thiab dysentery mixed hom (amoebic thiab kab mob);

• periodontitis, periostitis thiab lwm yam kab mob ntawm lub qhov ncauj kab noj hniav;

• gynecological inflammatory pathology;

• mob sinusitis;

• kab mob ntawm daim tawv nqaij thiab nqaij mos mos;

• postoperative kab mob;

• mob ntsws rwj.

Ib tug ntawm lawv, thiab lwm yam kab mob tshwm sim los ntawm aerobic thiab co kab mob rhiab rau qhov kev txiav txim ntawm cov tshuaj Cheebtsam.

Lees kev npaj "TSifran" postprandial. Ntsiav tshuaj yuav tsum tau noj nrog dej nyob rau hauv txaus qhov ntau. Tus neeg laus cov neeg mob noj cov tshuaj ib hnub ob zaug rau ib ntsiav tshuaj ntawm 500 / 600mg los yog ob tug 250 / 300mg. Cov neeg mob nyob rau hauv lub hnub nyoog ntawm kaum yim xyoo ntawm lub hnub nyoog, cov tshuaj yog tsis muab. Nws yog tsis pom zoo rau siv nyob rau hauv cev xeeb tub.

Contraindications rau kev siv ntawm cov piav tshuaj nyob rau hauv txoj kev kho yog cov nce rhiab heev rau lub Cheebtsam txoj kev ib feem ntawm tsifran thiab pathology ntawm cov ntshav, porphyria.