"Boudin" nqus tau pa: cov lus qhia rau kev siv, hauj lwm, muaj pes tsawg leeg thiab xyuas

Nyob rau hauv lub kho mob ntawm bronchial hawb pob nrog agonist beta-blockers yog lug siv nqus tau cov pa corticosteroids uas txo lub zaus thiab qhov ntawm lub sijhawm uas nws bronchospasm. Cov no pab pawg neeg ntawm cov tshuaj yog muab "Boudin" rau nqus tau pa. nyob rau hauv daim ntawv thov ntawm "Budenita" phau ntawv muaj cov lus qhia rau kev siv cov yeeb tshuaj, li ntawd, peb xyuam xim rau cov kev saib xyuas ntawm nws tseem ceeb nta thiab kev nuances ntawm daim ntawv thov thaum lub sij hawm nebuliser txoj kev kho.

Muaj pes tsawg leeg txhais tau tias "Boudin Steri-Neb" (ncua kev kawm ntawv)

Instruction qhia tias cov tshuaj yog ib ncua kev kawm rau inhalation, devoid ntawm cov xim thiab tsw, ntim rau hauv polyethylene vials ntawm 2 ml, muaj 1 mg (0.5 mg / ml) los yog 0.5 mg (0.25 mg / ml) lub active ingredient budesonide. Qhov no cov ntaub ntawv uas hais txog cov pharmacological pab pawg neeg ntawm glucocorticoid cov tshuaj hormones rau tshuaj pleev daim ntawv thov.

pharmacodynamics

Raws li pov thawj ntawm cov tshuaj "Boudin" qhia rau inhalation, budesonide (lub ntsiab active khoom sib ua zaub mov) muaj anti-tsis haum, anti-inflammatory thiab anti-edema nyhuv. Los ntawm stimulating protein lipocortin ntau lawm budesonide muaj ib tug inhibitory ntxim rau phospholipase synthesis, uas nyob rau hauv lem ua rau ib tug txo nyob rau hauv arachidonic acid synthesis, yuav txo tau nyob rau hauv zus tau tej cov prostaglandins thiab leukotrienes. Cov dab nyob rau cellular theem ua mus rau ib tug txo nyob rau hauv cytokine ntau lawm, txo cov tsiv teb tsaws ntawm macrophages thiab ua rau ib tug txo nyob rau hauv cellular infiltration. Thaum kawg no ua rau yus txo ntau ntawm inflammatory kev sib kho uas qhia zoo rau relieving bronchial hawb pob thiab stabilization ntawm nws cov kev soj ntsuam kev kawm.

Raws li pov thawj ntawm cov tshuaj "Boudin Steri-Neb cov lus qhia rau kev siv, nws kev siv ua rau kho tshiab ntawm rhiab heev ntawm lub bronchial tsob ntoo tshuaj, ceev rau ntawm cov bronchi. Qhov no nyob rau hauv lem thiaj li multiplicity ntawm tseeb siv, thiaj li tau nyiaj generated hnoos qeev bronchial secretion, thiaj li rhiab heev rau allergens, uas kuj muaj ib tug zoo ntxim rau cov kev soj ntsuam kev kawm ntawm tus kab mob.

Cov tshuaj muaj tsis muaj mineralocorticoid kev ua si, thiab muaj tsis muaj mauj los vim lub zos txiav txim, uas txo lub zaus thiab qhov ntawm cov kev phiv zoo taus rau lub caij nyoog lub siv.

Raws li pov thawj ntawm medicament "Boudin Steri-Neb cov lus qhia rau kev siv, analogues ntawm cov tshuaj no kuj zoo zam lub txim rau thiab tsis ua rau tshwm sim ntawm sab los txuam nrog kev siv ntawm muaj quag corticosteroids.

Tom qab ib tug tib daim ntawv thov ntawm cov kho nyhuv muaj tom qab ob peb teev, kom ib tug tshaj plaws heev tsis pub dhau 1-2 lub lis piam tom qab pib ntawm kev siv. Cov tshuaj yuav tsum zoo siv rau kev tiv thaiv ntawm bronchial hawb pob lub cev kev nyuaj siab, tab sis vim muaj ib tug ntev latent lub sij hawm, qhov pib ntawm tshuaj txiav txim suab tsis haum rau cov nyem ntawm mob tej yam kev mob uas muaj bronchospasm.

tshuaj

Lub tshuaj no yog muab siv ib tug Cav Tshuab Pa Tshuaj. Thaum nqus tau cov pa budesonide zoo pos huab settles rau ntawm qhov chaw ntawm lub bronchial tsob ntoo. Hais txog 15% ntawm cov tshuaj vim haum nyob rau hauv lub bronchial lumen nkag mus rau hauv mauj kev thiab ntxiv metabolized los ntawm kev siv cytochrome system rau zoo tsaug zog metabolites (lawv cov kev ua txog li 100 lub sij hawm tsawg tshaj li cov kev ua ntawm cov pib cov ntaub ntawv uas). Hais txog 70% ntawm cov tshuaj no yog tas los ntawm ob lub raum los ntawm txoj kev, thiab txog 10% yog tas los ntawm cov hnyuv.

indications

Raws li qhov yooj yim tshuaj budesonide thiab nws analogues muaj qhia rau cov kev kho mob thiab kev tiv thaiv tus mob hawb pob tawm tsam, lub ineffectiveness ntawm kev siv xim beta-adrenergic agonist rau kev tiv thaiv ntawm tus kab mob thiab stabilization ntawm kev soj ntsuam daim duab, raws li zoo raws li los txo cov tshuaj txhaj koob tshuaj ntawm qhov ncauj glucocorticoid agents. Cov tshuaj muaj lawm siv tau ntse rau cov kev kho ntawm stenotic laryngotracheitis thiab mob obstructive koj muaj teebmeem kev kab mob.

Contraindications

"Boudin Steri-Neb" (ncua kev kawm ntawv rau nqus tau pa) yog ua rau lub xub ntiag ntawm kev tsis haum tshuaj mus rau ib los yog ntau tshaj Cheebtsam ntawm nyob tus yeees ntawm cov tshuaj, raws li zoo li cov me nyuam nyob rau hauv lub hnub nyoog ntawm 6 xyoo. Nrog zoo saib xyuas cov tshuaj no yog tshuaj rau pulmonary tuberculosis, lub yeej ntawm ua pa kab mob, kab mob, fungal microflora, lub siab. Barring kev siv ntawm cov tshuaj nyob rau hauv lub xub ntiag ntawm kis kab mob tshwm sim los ntawm lub zos immunosuppressive ntxim rau cov qog ua kua uas tej zaum yuav raug nyob rau hauv ib tug yuav txo tau ntawm tiv thaiv kab mob cov lus teb thiab kab mob kev vam meej.

phiv

Vim lub fact tias cov tshuaj yog muab los ntawm nqus tau pa siv ib tug Cav Tshuab Pa Tshuaj, ib tug siab yuav tshwm sim ntawm dryness ntawm lub qhov ncauj mucosa thiab lub Upper pa ib ntsuj av tau, koj mob caj pas thiab voos, txawv txawv thiab tsis kaj siab saj, txhaws qa, los yog txhaws qa, hnoos. Qhov no yog vim subsidence mikrochastichek tshuaj nyob rau mucosal nto.

Heev tsis tshua cai ntshawv siab ntawm poob siab system, uas manifest lawv tus kheej nyob rau hauv daim ntawv ntawm nervousness thiab muaj zog excitability ntawm lub Neuro-puas siab puas ntsws, tus cwj pwm mob, mob taub hau. Tsis tas li ntawd, cov neeg mob ua ntawv thov "Boudin" tej zaum ua kom ua xua tau muab sau raws li urticaria, khaus khaus los yog liab ntawm daim tawv nqaij, spasm ntawm bronchial du nqaij, thiab cov kev loj hlob ntawm Candidiasis ntawm lub qhov ncauj kab noj hniav thiab txoj hlab nqos mov.

Cov tshwm sim ntawm paradoxical bronchoconstriction thiab hnyav dyspnea tom qab pib ntawm thawj koob tshuaj nqus tau cov pa vim irritating kev txiav txim ntawm cov tshuaj nyob rau hauv caj pas mucosa. Nrog rau txoj kev loj hlob ntawm no sab nyhuv nqus tau pa nws yog pom zoo kom mus nres thiab kom taw ib tug lwm txoj kev kho mob.

Dua li ntawm qhov uas tsis muaj bioavailability ntawm cov tshuaj thiab nws cov feem ntau lub zos los, lub caij nyoog siv yuav tsim mauj los ntawm glucocorticoids. Qhov no yog manifested inhibition ua si ntawm lub adrenal cortex, tseg ntawm txoj kev loj hlob nyob rau hauv cov me nyuam, txo nyob rau hauv cov pob txha ntxhia ceev, txoj kev loj hlob ntawm kev ua txhaum ntawm tus saib.

Nyob rau hauv tej rooj plaub (tsis tshua muaj) tej zaum yuav ua rau daim tawv nqaij voos thaum uas siv cov Cav Tshuab Pa Tshuaj daim npog qhov ncauj. Nyob rau hauv thiaj li yuav tiv thaiv no yam tab kaum yuav tsum tau siv tua kab mob kev daws teeb meem rau ib tug daim npog qhov ncauj, thiab tom qab nqus tau pa ntawm daim tawv nqaij nyob rau hauv khiav dej sov. Koj yuav tau tso cov nro roj hmab bands tuav lub daim npog qhov ncauj ntawm lub ntsej muag. Ib tug zoo lwm txoj yuav pab raws li kev siv ntawm ib tug ncauj npog ncig sab los yog tus pas tshuab rau nqus tau pa.

Siv nyob rau hauv cev xeeb tub thiab lactation

Cov lus qhia nyob rau hauv "Boudin" xav cov tshuaj yuav tsum tau siv nrog ceev faj nyob rau hauv cev xeeb tub cov poj niam thiab lub sij hawm pub niam mis (txawm tias cov ntaub ntawv nyob rau hauv cov khoom nkag tsis tuaj kawm ntawv nyob rau hauv leej niam lub mis nyuj). Cov tshuaj no yog pom zoo kom yuav tsum tau tsuas yog siv thaum nws cov kev pab mus rau leej niam outweigh cov tau phiv los thiab teeb meem mus rau lub fetus. Yog li ntawd nws yog tsim nyog los siv qhov tsawg kawg nkaus zoo budesonide nyob rau hauv ib koob tshuaj uas tso cai rau rau tag nrho cov tswj ntawm tus kab mob.

Tshuaj kev sib tshuam

Nyob rau theem ntawm kev sis raug zoo ntawm tus kws formulation yog sib xws nrog ib tug isotonic tshuaj ntawm sodium tshuaj dawb, raws li zoo li lwm yam nqus tau cov pa beta-agonists, mucolytics thiab expectorants. Nyob rau hauv thiaj li yuav nce miv nyuas siv zug thiab ib tug kho nyhuv ntawm bronchial spasm relieving tshuaj cov pab pawg yuav tsum muab tso rau ua ke nyob rau hauv lub Cav Tshuab Pa Tshuaj chamber. Sib koom bronchodilators tsis tsuas pab txoj kev khiav ntawm "Budesonide" nyob rau hauv bronchoalveolar tsob ntoo, tab sis tseem muaj txhawb rau nws ntxaum allergic rau hauv lub lumen.

Vim hais tias ntawm kev koom tes ntawm cytochrome P450 enzymes pab pawg neeg nyob rau hauv lub metabolism ntawm budesonide koob tshuaj yuav tsum tau saib thaum uas siv cov tshuaj uas mluas los yog stimulating ua si ntawm lub enzyme. Tsis pom zoo rau ob leeg siv tshuaj nrog noj tshuaj xws li "ketoconazole" thiab "Itraconazole", raws li qhov no tej zaum yuav ua rau ib qho kev nce rau hauv lub concentration ntawm "budesonide" ntshav.

Medicaments uas ua rau kom cov kev ua ntawm microsomal enzymes ( "Phenobarbital", "Phenytoin", "Rifampicin") txo kev ua si "budesonide".

dosing

Zoo nkauj yooj yim siv, "Boudin" rau nqus tau pa. Cov lus qhia rau kev siv qhia yuav tsum tau siv ib tug Cav Tshuab Pa Tshuaj rau kev kho mob. Lub tshuaj no yog muab tso rau hauv lub nebuliser ntaus ntawv, thiab nqus tau cov pa. Lub caij ntawm nqus tau pa thiab ntau npaum yuav tsum tau xaiv nyob rau hauv txhua rooj plaub noj mus rau hauv tus account tus soj ntsuam mob ntawm tus neeg mob thiab cov heev ntawm tus kab mob thaum uas siv cov tshuaj "Boudin" nqus tau pa. Instruction rau cov me nyuam los ntawm 6 lub hlis mus rau 12 xyoo cov ntsiab lus rau lub sij hawm ntawm budesonide ob zaug ib tug tsawg npaum li cas. Rau cov neeg mob laus tshaj 12 xyoo, tus txij nkawm koob tshuaj yuav tsum tau tom ib lub zuj zus.

Yog hais tias tsim nyog, "Budenita" ua ke nrog qhov ncauj glucocorticoid tshuaj pom zoo kom ua rau kom cov tshuaj ntawm "Budenita" rau kev tiv thaiv ntawm tshwm sim thiab txo cov kev mob ntawm sab los.

Xyuas

Kho cov kws kho mob thiab cov neeg mob txaus siab miv nyuas siv zug ntawm cov tshuaj. Qhov no yog muaj tim khawv los ib tug saib xyuas ntawm tus (ncua kev kawm ntawv rau nqus tau pa Teva «Boudin" - ib tug zoo nkauj nrov yeeb tshuaj) formulation. Ib tug cwj pwm zoo tsim qis tshwm sim ntawm cov kev phiv thiab zoo heev kev kho mob. Kev xav txog lub "Boudin" formulation rau nqus tau pa rau cov me nyuam (kev qhia ntawv, cov tshuaj muab nyob rau hauv tsab xov xwm) muaj zoo leej niam, uas yog tseem vim cov uas tsis muaj cov xwm txheej ntawm cov kev phiv. Tsis mob nqus tau pa siv nebulizers (uas yuav tsum tau ua nyob rau hauv ib tug ntau yam ntawm cov khoom ua si) nyob rau hauv cov me nyuam yaus kuj tau hais nyob rau hauv dej siab ntawm tus siv ntawm cov tshuaj, los yog nws analogues.

overdose

Nyob rau hauv mob overdose mob loj heev soj ntsuam cov tsos mob muaj cai. Kev kho mob yog symptomatic, nrog rau cov abolition ntawm cov tshuaj thiab lub sij hawm ntawm ib tug luv luv-acting cov hlab ntsws qhib txiav txim hom.

Nws yuav tsum tau borne nyob rau hauv lub siab hais tias nrog heev siv "Budenita" nyob rau hauv koob tshuaj tshaj sredneterapevticheskih yuav tsim kev phiv ntawm ib tug mauj theem (hypercortisolism, kev nyuaj siab ntawm adrenal muaj nuj nqi). Qhov no yog muaj tim khawv los "Boudin" inhalant kev qhia ntawv. Nws nqi yog muaj nyob rau long-term siv ntawm cov tshuaj raws li ib tug thawj txoj kev kho rau bronchial hawb pob.

Cais kev taw qhia thiab pab tswv yim

Cov lus qhia rau kev siv ntawm cov tshuaj "Boudin" hais tias hais tias nws yog tsis tsim los daws mob nres ntawm bronchospasm. Qhov nruab nrab lub sij hawm ntawm lub kho nyhuv ntawm txog 10 hnub, tab sis nws muaj peev xwm muab tau ntau zog los ntawm qhov kuaj nyob rau hauv lub lumen ntawm lub bronchial tsob ntoo los yog ib tug loj npaum li cas ntawm khov hnoos qeev secretion. Nyob rau hauv cov ntaub ntawv no nws tseem tau los ua kev cai cov kev kho mob nyob rau hauv ua ke nrog nrog qhov ncauj glucocorticoid tom hloov xwb "Boudin Steri-Neb" nqus tau pa.

Cov lus qhia mus rau yeeb tshuaj hais tias, txawm hais tias qhov tshwm sim ntawm cov kev phiv ntawm lub cev qib yog tsawg, nws yog ib qho tseem ceeb rau titrate qhov tsawg kawg nkaus zoo kho koob tshuaj rau siab tshaj plaws cov nyhuv. Nyob rau hauv ua ntawv thov cov tshuaj nyob rau hauv cov me nyuam nrog ib tug saib kom raws sij hawm qhia kom paub txog kev phiv los yuav tsum tau tas li saib xyuas tus me nyuam txoj kev loj hlob tshaj ib lub sij hawm ntev ntawm lub sij hawm. Nrog rau txoj kev loj hlob ntawm sab los yuav tsum raug txo kom tsawg li tsawg tau zoo koob, uas tso cai rau tswj tawm tsam tus mob hawb pob.

Rau kev tiv thaiv ntawm fungal kab mob nyob rau hauv lub qhov ncauj kab noj hniav ntawm tus neeg mob yuav tsum tau paub txog cov kev yuav tsum tau yaug lub qhov ncauj thiab tshem tawm cov seem tom qab txhua nqus tau pa. Qhov no yeej txhawb restoration ntawm lub zos tiv thaiv thiab lub qhov ncauj qog ua kua.

Kev nta Siv

Nqus tau pa "Budenita" siv ultrasonic nebulizers txhob. Lub koob tshuaj ntawm cov tshuaj yuav tsum tau muab los xam noj mus rau hauv tus account lub particular kev nta ntawm lub Cav Tshuab Pa Tshuaj (noj mus rau hauv tus account lub pa txaus tus nqi, qhov ntim ntawm lub nebuliser thiab t. D.) Thiab tus neeg mob tus mob.

Ua ntej siv cov tshuaj "Boudin" nqus tau pa Cav Tshuab Pa Tshuaj nyob rau hauv lub Cav Tshuab Pa Tshuaj kev qhia no yog yuav tsum tau yuav tsum tau kawm. Qhov no yuav tsis txhob muaj cov kev twb kev txuas ntawm cov ntaus ntawv thiab cov inefficient siv ntawm cov tshuaj. Yog hais tias lub Cav Tshuab Pa Tshuaj yog siv rau cov thawj lub sij hawm, nws yog pom zoo kom ntsuam xyuas uas siv ib lub physiological sodium tshuaj dawb tov kom nws operability thiab yog ces siv tshuaj.

Ua ntej nqus tau pa lub box zoo tu qab tso yas ampule, nws yog qhib los ntawm tearing hau, cov tshuaj yog muab tso rau hauv lub Cav Tshuab Pa Tshuaj chamber ntawm lub apparatus, muab tso rau hauv daim npog qhov ncauj rau lub ntsej muag (los yog clamped ncauj npog ncig sab) thiab pub rau cov huab cua txaus. Thaum lub sij hawm inhalations siv lub ncauj npog ncig yuav tsum ua pa tsuas yog los ntawm koj lub qhov ncauj (hnav tshaj qhov ntswg tshwj xeeb clip). Thaum siv ib pa daim npog qhov ncauj daim ntawv thov optionally qhov ntswg clip.

Rau nqus tau pa nws yog pom zoo kom siv cov nebuliser mus rau ib tug valve ntaus ntawv uas muab txhaj zoo aerosol tshuaj ncaj qha mus rau lub sij hawm ntawm nqus tau pa thiab kaw lub qhov hluav taws xob ntawm cov tshuaj nyob rau ntawm lub lub sij hawm ntawm tas sij hawm. Qhov no yuav tsub cov tshuaj tus me nyuam nyob rau hauv bronchoalveolar ntoo thiab thiaj li tsis noj tshuaj thaum lub sij hawm exhalation.

"Boudin Steri-Neb": analogues, nqe

Drug analogues "Boudin Steri-Neb" yog cov tshuaj xws li "Pulmicort" thiab "Pulmicort Turbuhaler", "Kortimen", "Tafen", "Budoster", "Budenofalk" thiab ntau lwm tus neeg. Thaum cov tshuaj, raws li nyob rau hauv cov kev npaj "Boudin" inhalation, cov kev qhia ntawv yog tib yam vim yog lub xub ntiag ntawm lub tib lub active ingredient. Cov ntaub ntawv nqi ntawm cov tshuaj nyob rau lub tsev muag tshuaj network thiab lub cheeb tsam, raws li zoo raws li lub tshuaj. Nyob rau nruab nrab, cov nqi yog hom twg los ntawm 650 mus 2550 rubles.

xaus

Zoo heev medicament rau cov kev kho mob thiab kev tiv thaiv tus mob hawb pob tawm tsam yog "Boudin" nqus tau pa. Cov lus qhia mus rau yeeb tshuaj muab ncauj lus kom ntxaws txog cov kev tshuaj thiab tej yam kev mob ntawm kev siv ntawm cov tshuaj no. Muab budesonide daim ntawv thov nyob rau hauv raws li cov lus qhia thiab pom zoo noj tshuaj npaum cas ntawm cov medicament muab ib txoj kev kho. Yog hais tias rau ib co yog vim li cas koj yuav tsis tau tus thawj, muaj analogues. "Boudin Steri-Neb" (tus nqi lus qhia uas koj muaj tam sim no lub npe hu) yuav cawm koj los ntawm ntau cov kab mob ntawm lub pa system.