Cov lus qhia rau daim ntawv thov "Gepadif". Xyuas thiab Analogues

Cov tshuaj zoo li "Gepadif" yog dab tsi? Cov lus qhia siv, kev tawm tswv yim txog txoj kev siv tshuaj ntawm no yuav tham txog hauv qab no. Tsis tas li ntawd, los ntawm tsab xov xwm uas tau hais los no koj yuav kawm txog qhov cuabyeej uas tau hais rau yog, daim ntawv twg yog xa tawm, nws muaj dabtsi, thiab lwm yam.

Muaj pes tsawg, cov ntaub ntawv tso tawm ntawm ib yam khoom muag

Tam sim no, cov tshuaj no yog ua los ntawm cov ntaub ntawv hauv qab no:

• Lub hmoov npaj rau qhov kev npaj ntawm ib qho dej txhuav dej, uas muab tso rau hauv vials thiab cov pob khoom ntawm cardboard, ntsig.

Cov kab mob ntawm cov tshuaj no muaj xws li carotene orotate, carnitine hydrochloride, antitoxic feem, adenosine, pyridoxine hydrochloride thiab cyanocobalamin.

• Cov tshuaj "Gepadif" - tshuaj ntsiav. Kev qhia rau cov xeev siv tias daim ntawv ntawm cov tshuaj no tau ua nyob rau hauv ib qho chaw uas muaj xim dub nrog daim ntawv sau kabmob Hepadif thiab HSD. Cov ntsiab lus yog nplua hmoov ntawm lub teeb daj nrog lub paj tawv taum. Cov kua tshuaj kua ntsev mus rau ntawm cov kab mob thiab cov thawv ntawv. Cov lus sau ntawm cov tshuaj nyob rau hauv cov lus nug muaj xws li: carotene orotate, antitoxic feem, pyridoxine hydrochloride, cyanocobalamin, adenine hydrochloride thiab riboflavin. Nws yuav tsum raug sau tseg hais tias qhov no txhais tau tias muaj cov nram qab no adjuvants: hlau oxide dub, anhydrous lactose, liab hlau oxide, magnesium stearate, gelatin, hlau oxide daj, anhydrous colloidal silica, titanium dioxide thiab microcrystalline cellulose.

Pharmacology ntawm tus kws kho mob

Dab tsi yog qhov tshuaj hauv kev saib xyuas? Cov lus qhia rau kev siv hais li cas? "Gepadif" yog kev npaj ua ke. Lub tswv yim ntawm nws qhov kev txiav txim yog vim muaj kev cuam tshuam ntawm cov khoom sib cais.

Cov tshuaj muaj peev xwm tsim kho cov txheej txheem biosynthetic nyob rau hauv lub cev thiab cov txheej txheem ntawm cov metabolism hauv lipid, tiv thaiv necrosis ntawm hepatocytes, normalize proliferation ntawm hepatocytes, restore lub siab daim siab ua haujlwm, thiab cov qoob loo ntawm cov enzymes.

Ntais ntawm cov khoom muag

Yam khoom zoo li cas hauv cov tshuaj "Gepadif"? Cov lus qhia rau siv tau tias cov adenosine uas muaj nyob hauv qhov kev npaj yog muaj nyob rau hauv cov nucleic acids, coenzymes thiab zoo txhua lub hlwb ntawm lub cev. Ntxiv mus, nws yog ib qho endogenous nucleoside thiab tswj tau cov txheej txheem ntawm hematopoiesis. Qhov no tivthaiv kom cov pob txha ntawm cov tawv nqaij ntawm cov hlab ntsha, thiab kuj ua rau lub cev ntawm O2 hepatocytes.

Cov tshuaj vitamin B (pyridoxine, riboflavin, cyanocobalamin) ua li cas hauv cov cuab yeej no? Vim lawv qhov kev npaj "Gepadif" yuav siv sij hawm ib qho kev koom tes ua ke ntawm qhov tseem ceeb tshaj ntawm cov amino acids (tryptophan, methionine, cysteine thiab lwm tus) thiab OVR. Lawv kuj ua rau lub cev tsis muaj zog thiab ua rau cov roj, cov protein thiab carbohydrate metabolism hauv lub cev.

Cov antitoxic feem nyob hauv cov tshuaj muaj ib qho kev hloov thiab irreplaceable amino acids, vim nws muaj antioxidant thiab detoxifying teebmeem.

Nrog rau carnitine, qhov no tivthaiv yuav siv ib feem ntawm cov khoom ntawm fatty acids, cov kev cai ntawm cov roj metabolism hauv thiab cov khoom noj khoom haus. Nws kuj tseem yuav tsum tau sau tseg tias cov tshuaj no yog tuaj yeem ua kom muaj cov kab mob hauv lub cev, ua rau lub hlwb zoo rau cov tshuaj insulin thiab pab ua kom haum ntawm carbohydrates hauv cov hnyuv, uas tsis tshua muaj neeg tsim nyog los pab txhawb nws lub cev.

Kinetic Properties

Lub nqus ntawm cov tshuaj "Gepadif" li cas? Kev siv ntawm cov tshuaj hais lus txhawb nqa kev tso tawm ntawm ib tug complex ntawm active cheeb tsam nyob rau hauv lub duodenum. Tom qab no, instantaneous nqus ntawm carnitine, vitamins, antitoxic feem thiab adenine yuav siv sij hawm qhov chaw tag nrho ntawm qhov hnyuv me me.

Qhov faib ntawm cov tshuaj no tsis yog nyob hauv cov hnyuv, tab sis kuj nyob hauv siab thiab lub raum. Qhov siab tshaj plaws ntawm cov kab mob riboflavin tau pom hauv cov hlwb myocardial.

Cov metabolism hauv pyridoxine yog ua tiav hauv lub siab. Qhov no tivthaiv faib rau hauv daim siab, as Well as hauv cov leeg nqaij thiab lub hlwb. Cov khoom ntawm metabolism yog tsuas yog excreted los ntawm ob lub raum.

Thaum cov tshuaj siv cov tshuaj tua kabmob (intravenously), nws cov khoom raug faib tawm hauv cov leeg nqaij, lub siab, hlwb, lub raum thiab cardiomyocytes. Metabolism hauv kev daws kuj tshwm sim nyob rau hauv lub siab, thiab cov khoom ntawm cov metabolism hauv cov kis tau los ntawm ob lub raum.

Cov kev qhia rau kev noj tshuaj thiab siv cov hmoov

Cov mob rau tus neeg mob tuaj mus sau cov tshuaj rau hauv nqe lus nug zoo li cas? Cov lus qhia rau kev siv hais li cas? "Gepadif" yog qhia rau txoj kev kho mob ntawm cov kab mob nram no:

• Cirrhosis ntawm lub siab;
• Kab mob siab mob ntev thiab mob ntev;
• Rog siab mob siab;
• Tshuaj tsw qab rau daim siab;
• Exogenous lom;
• Intoxication, uas yog tshwm sim los ntawm kev siv tshuaj tiv thaiv antitumor thiab tshuaj tiv thaiv kab mob ntsig.

Contraindications rau kev siv cov tshuaj

Thaum twg koj yuav tsum tsis siv cov kua tshuaj thiab cov tshuaj ntsiav "Gepadif" (ntsiav tshuaj)? Kev qhia rau kev siv tau qhia tias cov nyiaj no raug tiv thaiv rau:

• Kev ua xua rau cov cheebtsam tshuaj;
• Erythema, nephrolithiasis, erythrocytosis thiab thromboembolism;
• Nyob rau hauv lub hnub nyoog ntawm 7 xyoo;
• Hlav ntawm cov hnyuv (tshwj xeeb tshaj yog nyob rau theem ntawm kev sib zog).

Lus qhia rau kev siv

"Gepadif" nyob rau hauv daim ntawv ntawm cov tshuaj tiv thaiv yog noj ntawm ncauj, ntxuav nrog dej (tag nrho). Qhov kev siv tshuaj tiv thaiv kab mob ntawm qhov kev kho no, nrog rau kev kho mob ntev npaum li cas, yog txiav txim los ntawm tus kws kho mob.

Feem ntau qhov tshuaj txhua hnub ntawm cov tshuaj rau cov neeg laus yog ob lub hnoos peb zaug ib hnub. Raws li cov menyuam yaus ntawm 7 xyoo, lawv tau sau peb lub ntsiav tshuaj hauv ib hnub (hauv 3 faib koob tshuaj).

Yog tias tus neeg mob muaj teeb meem nrog kev siv ib qho tshuaj ntsiav, nws cov khoom tso cai rau yaj tawm hauv dej me me lossis kua txiv (tsuas yog tsis muaj mis nyuj).

Nws kuj tseem yuav tsum tau sau tseg tias yog cov tshuaj tsis muaj kab mob rau tus neeg mob, cov tshuaj tso cai ntawm cov tshuaj yuav tsum tau qhia.

Yuav ua li cas kom ua los yog ua nyxes nrog ib tug npaj "Gepadif"?

Cov lus qhia hais tias txhua hnub kev siv tshuaj rau cov neeg laus yog 8.625 mg ib kilogram ntawm lub cev qhov hnyav. Kev sib koom tes ntawm tus neeg saib xyuas no yog 1 zaug hauv ib hnub.

Ua ntej nqa tawm ib qho kev txhaj tshuaj, cov vial txheem twb yaj tsib feem pua zib tov nyob rau hauv ib tug ntim ntawm 500 ml.

Kho ntawm cov koob tshuaj ntawm cov tshuaj rau cov neeg laus tsis tas yuav tsum tau.

Tej teebmeem

Dab tsi yog cov kev xav tsis haum uas tshwm sim los ntawm cov tshuaj no? Cov lus qhia rau kev siv hais li cas? "Gepadif" yog qhov ua kom haum zoo. Txawm tias nyob rau hauv tej rooj plaub lawv yeej tseem tshwm sim raws li nram no phiv: kem plab, mob taub hau, xeev siab, cem quav, tawm pob, tso zis, daj, ntuav, angioedema, raws plab, daim tawv nqaij ua pob ua xyua.

Cov tshuaj ntawm cov tshuaj ntau dhau

Thaum noj tshuaj ntau dhau ntawm tus neeg mob no muaj xws li: peripheral neuropathy, raws plab, muaj kev phiv tshuaj ntxiv, ntuav.

Yuav kho cov mob zoo li no, tus neeg raug tsim txom yog tus kws khomob lub plab thiab kev kho mob, thiab kev ua kom muaj roj qaub thiab cov dej qab ntsev.

Kev sib cuam tshuam

"Gepadif" ua li cas nrog lwm cov yeeb tshuaj? Kev qhia qhia tau hais tias ua ntej siv cov tshuaj no, nws yuav tsum tau nrog tus kws kho mob tham.

"Riboflavin" yog txwv tsis pub nrog "Streptomycin", txij thaum thawj zaug txo cov kev siv tshuaj tua kab mob. Ntxiv thiab, cov metabolism ntawm tus neeg sawv cev nug, nrog rau nws cov nyhuv rau hauv lub plawv, thiaj li muaj cov tshuaj tiv thaiv tricyclic antidepressants.

Vitamin B6, ib feem ntawm lub "Gepadifa", thiaj li muaj cov nyhuv ntawm "Levodopa" thiab thiaj li muaj cov tsos ntawm sab tshua antitubercular agents thiab "Isoniazid".

Lub txiaj ntsim ntawm vitamin B12 yog cuam tshuam los ntawm cawv, calcium npaj, para-aminosalicylic acid thiab "cimetidine".

Xyuas thiab Analogues

Muaj ntau ntau yam analogues ntawm "Gepadif". Lawv muaj peev xwm txawv tsis yog nyob rau hauv nqe, tab sis nyob rau hauv muaj pes tsawg leeg. Cov tshuaj xws li nram no: Tavamin, Oktamin Plus, Heptor, Carnitine, Elkar, Carnivit, Almiba, Carnigel, Carniten, Le Carnita, Agvantar "," Stimol "," Heptral "," Steator ".

Raws li nws tau hais los saum no, cov tshuaj hauv cov lus nug muaj ntau qhov kev nqis tes ua. Yog li ntawd, nws yog hais rau ntau yam kab mob. Txawm li cas los xij, feem ntau cov tshuaj no yog siv los ua ib qho ntawm txoj kev kho mob los txhawb txoj haujlwm ntawm lub siab.

Cov tswvyim ntawm cov neeg tau txais kev pabcuam txog kev siv tau thiab kev ua haujlwm ntawm cov tshuaj no yog faib. Qhov no yog vim qhov tseeb tias qhov tshwm sim los ntawm kev kho nrog cov tshuaj no tej zaum yuav txawv, nyob ntawm seb qhov puas ntawm kev puas tsuaj, hom kab mob thiab cov tshuaj noj nrog lwm cov tshuaj. Yog li, xaiv cov tshuaj no tsuas yog tus kws kho mob tshwj xeeb tom qab kuaj xyuas tus neeg mob.

Nws kuj tseem yuav tsum tau sau tseg tias ntau tus neeg mob tsis txaus siab tias thaum tau txais "Gepadif" lawv feem ntau muaj kev phiv tshuaj rau hauv cov teeb meem nrog quav thiab xeev siab.