Kua tsib acid sequestrants, tshuaj: daim ntawv teev

fatty acid sequestrant tshuaj yog hu ua, yog tau txo cov ntshav roj. Qhov no koom haum pab tshuaj siv nyob rau hauv kev kho mob. Muaj yog ib tug meej kev faib ntawm lipid tej tshuaj, uas tiv thaiv cov roj uas txhaws tsim nyob rau hauv cov ntshav. Sequestering ua hauj lawm yog muaj nyob rau hauv no cais. Nws yog nyob ntawm, muaj ib tug ntau yam ntawm cov cuab yeej, uas yog zoo li tus mechanism ntawm qhov kev txiav txim. Feem ntau cov paub cov kua tsib acid sequestrants - tshuaj "Colestipol", "Cholestyramine", "colesevelam."

Uas muaj mob plawv yog txo los ntawm sequestering zog, xws li ischemia. Soj ntsuam kev qhia cov hauj lwm zoo ntawm cov SCF nyob rau hauv cov nram qab no cov ntsiab lus:

• teeb meem ntawm coronary cim yog slowing;
• txo tuag los ntawm myocardial infarction.

Cov tshuaj nyob tus yeees ntawm cov tshuaj tso cai rau lawv kom muaj xws li cov pawg ntawm ion pauv resins. Qhov no siab molecular yuag hluavtaws tebchaw uas yog yeej tseem zoo insoluble polymers yog khoom muab kev koom tes nrog rau cov aqueous nruab nrab nyob rau hauv lub ion pauv txheej txheem. Hais tias yog dab tsi sequestering kua tsib acids.

Lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj

Lo lus "sequestrant" txhais tau tias "insulator", uas yog tshwm sim nyob rau hauv tib neeg lub cev kev rho tawm ntawm cov kua tsib acids. Cholesterol uake nrog cov kua tsib acids, uas nqa cov roj los ntawm lub siab uas txaus nyob rau hauv thiaj li yuav effect lub synthesis. Kua tsib acid circulating nyob rau hauv lub digestive system ua ntej lawv mus txog lub hnyuv qhov twg nws yog tsis yaim. Raws li ib tug tshwm sim, lub cev yog ib tug ntau ntawm cov nqi tshuaj rau lub neej.

Pib tau yog lipoproteins uas muaj ib tug uas tsis muaj kev ceev. Qhov no thiaj li hu ua cov cholesterol.

Txij li thaum ua hauj lwm cov kua tsib acid sequestrants (npaj piav nyob rau hauv kom meej hauv qab no).

Sequestrants tsis absorbed rau hauv cov hlab ntsha, yog li kev phiv yog tias muaj, yog qhov tsawg kawg nkaus theem, thiab lawv yuav tshwm sim heev tsis tshua muaj.

Cev Xeeb Tub thiab lactating cov poj niam lawv yuav siv tau rau cov yog vim li cas. Tsis tas li ntawd, cov me nyuam thiab cov tub ntxhais hluas nrog familial hypercholesterolemia noj cov tshuaj kom qeeb tus txheej txheem. Nws yog ib qho pub mob ntawm lub cev, nyob rau hauv uas lub pronounced roj thiab lub resulting txim.

Yog hais tias tsiv FFA li qub, koj yuav siv lawv rau ib tug heev lub sij hawm ntev. Noobyazatelno yuav tsum tswj cov roj cholesterol, daim siab enzymes thiab tej nqaij.

Statins nyob rau hauv ua ke nrog nrog FFA zoo dua nrog ntev chav kawm ntawm kev kho mob. Ib tug phem cholesterol yog txo los ntawm ib nrab. Yog hais tias muaj yog ib tug ua ke hyperlipidemia (thaum ib tug ntau ntawm cov nqaijrog nyob rau hauv cov ntshav), ces qhov kev tshwm sim yuav zoo dua los ntawm 70-75%. Raws li lub cev ua rau cov kua tsib acid sequestrants? Lub formulations yog feem ntau zoo taus.

Yuav ua li cas yog cov kev phiv?

Sab los tshwm sim heev tsis tshua muaj. Yog hais tias lawv yog, ces tsis muaj dab tsi loj heev rau lub cev tsis tig ib ncig. Tseem, ib txhia neeg tej zaum yuav ua tau ib tug manifestation ntawm cov nram qab no cov tsos mob dhau sai sai:

• cem quav;
• kem plab (dyspepsia);
• xeev siab;
• ntev li roj tsim nyob rau hauv cov hnyuv (flatulence);
• tsam plab;
• kub siab, thiab nws yog lub feem ntau ntau sab nyhuv ntawm cov kua tsib acid sequestrants.

Nyob rau hauv kev txiav txim kom tsis txhob muaj tej yam tsis zoo tshua nyob rau ib feem ntawm lub cev, koj yuav tsum haus dej kom ntau thiab noj thaum pib ntawm cov tshuaj nyob rau hauv me me koob tshuaj.

Thaum siv FFA cov me nyuam xav kom lawv muab hlau thiab folic acid. Tib mus kho mob nrog rau lwm cov tshuaj yuav ua rau cov neeg pluag haum ntawm active Cheebtsam. Ntawm no nws yog tsim nyog los soj ntsuam cov nram qab no txoj cai: sequestering haus ib teev tom qab siv lwm yam txhais tau tias, thiab rau plaub teev ua ntej.

Heev tsis tshua tau nqaij mob (myalgia), o ntawm lub caj pas (caj pas). Tsis tshua muaj neeg tsis tshua tshwm sim ntawm hnoos, mob nyob rau hauv lub rov qab, txias.

Contraindications

Tsis contraindications sequestering kua tsib acids? Tshuaj tsis kho nyob rau hauv cov nram no mob.

Thaum hyperlipidemia hom 3 thiab 4 (uas hem pathologies ntawm cov hlab plawv system) yog tsis pom zoo sequestrants. Yuav tsa triglycerides nyob rau hauv cov ntshav. Thaum ntaus los ntawm cov kua tsib duct (biliary mob npuas paug thiab ua kom tiav biliary rhuav txhua) yuav tsis muab cov ntaub ntawv medicaments. Yog hais tias ib tug neeg suffers los ntawm heev cem quav, cov tshuaj yuav tsuas thab qhov teeb meem no. Raum tus kab mob, mob plab ulcers, hemorrhoids, los ntshav - tag nrho cov contraindications rau SLC.

Nrog kev saib xyuas muab lawv rau cov neeg uas gastrointestinal mob, malabsorption syndrome (lus hnyuv haum, thiab tseem ceeb as-ham tsis yooj yim nyob rau hauv lub cev).

Tau xwb idiosyncrasy.

Cov nram qab no saib lub nrov tshaj plaws kua tsib acid sequestrants. Tshuaj (hauv daim ntawv kuj mus nrog koj tus kws kho mob) yuav tsum teem nyob rau hauv kev txiav txim los ntawm feem ntau nrov rau tsawg kawg nrov.

Cov tshuaj "Cholestyramine"

Nws tseem hu ua "Cholestyramine". Tiabsis cov yog insoluble ion pauv resins. Nws ua rau ib tug txo nyob rau hauv cov ntshav cov roj ntau ntau los ntawm ib tug peb lub hlis twg. Yog ib tug active losis tswvyim dabtsi kua tsib acids, whereupon lawv cais los ntawm cov tib neeg lub cev. Yog hais tias cov tshuaj yog tsim nyog los haus dej haus rau ib ntev lub sij hawm, ces koj yuav tau siv dej ntau. Statins txhim khu cov teebmeem, tab sis lawv cov concentration yog txo nyob rau hauv cov ntshav. Thaum muaj hnub nyoog ntawm 60 xyoo muab nrog ceev faj.

Medicament "Colestipol"

Nws yog ib tug high insoluble copolymer. Properties khi cov kua tsib acids yog heev me ntsis ntxiv rau nws tshaj tus "Kolestiramin".

Indications, tshwm sim thiab contraindications yog tib yam li cov tag nrho cov pab pawg neeg ntawm cov tshuaj. Lub ua ke ntawm "Kolestepola" thiab statins muab qhov zoo tshaj plaws cov nyhuv.

Tshuaj "colesevelam"

Tsis unpleasant saj thaj chaw ntawm cov khoom muaj txhawb mus rau lub fact tias nws yog nce siv nyob rau hauv kev sib piv nrog rau lwm cov tshuaj.

Koj cov ntaub ntawv sequestering kua tsib acids muaj sab los?

Tsis zoo los rau tus mob huam tau sau tseg. Tshua nrog rau lwm yam tshuaj ua tsis tau. "Colesevelam" tej zaum yuav siv tau rau cov kev kho mob ntawm cev xeeb tub thiab lactating cov poj niam.