"Lantsid": cov lus qhia rau kev siv, ib tug piav qhia ntawm cov tshuaj, analogues, xyuas

Ulcers ntawm lub digestive ib ntsuj av tau tus kab mob tej zaum yuav tshwm sim mam li nco dheev. Rau cov kev kho mob ntawm tus kab mob no yuav tsum tam sim ntawd sab laj ib txog tej gastroenterologist.

Tom qab ceev faj xeem tus kws kho mob yuav tsum muab anti-rwj tshuaj. Qhov zoo tshaj ntawm cov no yog cov tshuaj "Lantsid". Tus nqi ntawm cov tshuaj no yuav tsum tau teev tseg hauv qab no. Nyob rau hauv tas li ntawd, koj yuav kawm tau dab tsi zog yog xam qhovkev nyob rau hauv hais tias txhais tau hais tias, yog hais tias nws muaj tej yam analogues thiab yuav ua li cas kom zoo zoo noj.

Muaj pes tsawg leeg, hauj lwm, ntim thiab muaj pes tsawg leeg

Kev npaj "Lantsid" yog muab nyob rau hauv daim ntawv ntawm gelatin tsiav tshuaj (nyuaj). Lawv muaj ib tug turquoise xim thiab cov ntsiab lus nyob rau hauv daim ntawv ntawm cov dawb granules.

Lub active muaj nyob rau hauv cov tshuaj no yog lansoprazole. Tsis tas li ntawd lub tsiav tshuaj muaj xws li cov nram qab no pab txhawb nqa cov ntsiab: mannitol, povidone, lactose monohydrate, cetyl cawv, sucrose thiab hypromellose phthalate.

Saib cov tshuaj yog muag nyob rau hauv sawv hlwv packs thiab cartons.

nyhuv ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "Lantsid"? Cov lus qhia rau kev siv hais tias nws yog ib qho inhibitor ntawm H ⁺ K ⁺ -ATPase (proton twj tso kua mis). Nws metabolism yog nqa tawm nyob rau hauv hlwb (parietal) ntawm lub plab. Nyob rau hauv daim ntawv no lub active sulfonamide derivatives.

Qhov no tshuaj blocks lub tso pa tawm ntawm hydrochloric acid, zuj zus lawm basal thiab tsa secretion.

Nrog siab lipophilicity, nws txhais tau tias theej yooj yim penetrates rau hauv lub pais plab hlwb (parietal), thiab ces, ywm lawv niamntiav ib cytoprotective nyhuv, ua pa ntawm bicarbonate thiab ua oxygenation ntsiab digestive hloov khoom nruab nrog mucosa.

Lub twg thiab tus nqi ntawm inhibition ntawm basal thiab tsa secretion ntawm hydrochloric acid yog koob tshuaj-dependent. Nws pH yog nce tom qab 1-2 xuab moos thiab 2-3 teev tom qab haus ntawm 15 mg ntawm siv yeeb tshuaj thiab 30 feem.

Cov tshuaj no muaj tsis ntxim rau cov kom ntawm tus mob huam. Lub inhibitory nyhuv uas cov tshuaj no yog qhia nyob rau hauv thawj plaub hnub ntawm kev txais tos. Tom qab kawm tiav ntawm kev kho mob rau 40 teev acidity tseem tsawg kawg yog 50% ntawm basal theem.

tshem ntawm xws npaj yog tsis raug.

thaj chaw ntawm cov tshuaj

Kev npaj "Lantsid" (cov ntsiav tshuaj) nyob rau hauv lub plab mucosa ntaub ntawv IgA hais rau Helicobacter pylori los ntawm inhibiting txoj kev loj hlob ntawm H. pylori thiab ua cov kev ua ntawm lwm yam tshuaj.

Nws kuj txhais tau tias cheeb zus tau tej cov pepsin thiab pepsinogen tsub kom lub concentration hauv cov ntshav.

Lub kinetics ntawm cov tshuaj

Seb tshuaj yog absorbed "Lantsid"? Cov lus qhia rau kev siv hais tias qhov no haum txhais tau tias pib tam sim ntawd tom qab kev npaj yoojyim lub plab. Lub ncov concentration ntawm lansoprazole nyob rau hauv cov ntshav cai tom qab 1.7 teev.

Khoom noj khoom haus siv thiaj li haum thiab bioavailability ntawm cov tshuaj.

Lub ib nrab-lub neej ntawm lansoprazole yog hais txog ob teev. Qhov no tsis cuam tshuam rau lub caij ntawm hluav ntawm pais plab tso pa tawm.

Xaus tshuaj los ntawm lub cev yog nqa tawm nrog cov kua tsib thiab zis.

zaj lus tim khawv

Uas kab mob feem ntau zoo behaves tshuaj "Lantsid"? Xyuas hais tias nws txhais tau hais zoo kho cov nram qab no cov kab mob:

• reflux esophagitis;
• uas tsis yog-rwj dyspepsia;
• peptic rwj kab mob (exacerbation) ntawm txoj hnyuv;
• esophagitis, erosive thiab ulcerative;
• ulcers ntawm lub digestive ib ntsuj av tau kev nyuaj siab;
• Ellison - Zollinger.

Contraindications

Nyob rau hauv tej rooj plaub, koj muaj peev xwm tsis tau lub tsiav tshuaj "Lantsid"? Cov lus qhia rau Siv hais tias contraindications xam tau tias yog txhais tau tias yog cov li nram qab no rau tus neeg mob tus mob:

• kev pub niam mis;
• thawj peb lub hlis uas cev xeeb tub;
• phem hlav nyob rau hauv lub digestive ib ntsuj av tau;
• Npau taws me ntsis rau lub Cheebtsam ntawm cov tshuaj.

Yuav ceev faj ntawm no yeeb tshuaj yog tshuaj rau cov neeg uas muaj lub siab tsis ua hauj lwm, lub thib ob thiab thib peb trimesters uas cev xeeb tub, cov neeg laus cov neeg mob thiab cov neeg mob uas muaj ib tug muaj hnub nyoog.

Medicament "Lantsid": cov lus qhia rau kev siv

Xav capsule coj hais lus. Lawv yuav tsum tau nqos tag nrho tsis muaj kev zom khoom.

Thaum erosive thiab ulcerative esophagitis thiab peptic rwj ntawm lub plab tshuaj 30 mg txhua hnub rau 4-8 lub lis piam. Yog hais tias qhov kev kawm, ntau npaum yog nce mus rau 60 mg ib hnub twg.

Thaum muaj kev nyuaj siab ulcers thiab peptic rwj kab mob 12 duodenal rwj tshuaj yog pom zoo kom noj 30 mg ib hnub twg nyob rau hauv ib kauj ruam. Ua dua nyob rau hauv thaum sawv ntxov, nyob noj tshais, rau 2-4 lub lis piam.

Lub syndrome Zollinger - Ellison tshuaj ntau npaum yog tom ib lub zuj zus.

Thaum Reflux esophagitis noj tshuaj rau ib lub hlis nyob rau hauv ib tug npaum li ntawm 30 mg ib hnub twg.

Yuav kom tshem tawm Helicobacter pylori tshuaj no yog pom zoo kom siv 30 mg ib hnub ob zaug. Yuav kom txhim kho kho tau medicament ua ke nrog tshuaj tua kab mob xws li "clarithromycin" los yog "amoxicillin". Kev kho mob yuav tsum kav tsawg kawg yog ib lub lim tiam.

Nyob rau hauv ulcerative dyspepsia npaj siv rau 2-4 lub lim piam ntawm ib koob tshuaj 15-30 mg ib hnub twg.

Thaum lub siab tsis ua hauj lwm, raws li zoo raws li cov neeg laus pib kho nrog ib nrab-koob tshuaj. Ces lawv nce mus rau lub pom zoo, tab sis tsis ntau tshaj 30 mg ib hnub twg.

phiv

Medicament "Lantsid Kit" yuav ua rau cov nram qab no sab tshua:

• mob taub hau, ntxhov siab vim, malaise, nkees nkees, kiv taub hau, kev nyuaj siab;
• txo los yog nce nyob rau hauv qab los noj mov, hyperbilirubinemia, xeev siab, hnyuv Candidiasis, mob plab, txhawb siab transaminases, raws plab, ulcerative mob plab, cem quav;
• hnoos, Upper pa ib ntsuj av tau kab mob, pharyngitis, khaub thuas syndrome, txhaws ntswg;
• daim tawv nqaij sawv pob, erythema multiforme, photosensitivity;
• anemia, thrombocytopenia;
• alopecia, myalgia.

tshuaj cov kev sib tshuam

Kev npaj "Lantsid Kit" slows tshem tawm cov neeg ua hauj uas yog metabolized nyob rau hauv lub siab los ntawm microsomal oxidation (e.g., xws li "Phenytoin" "Diazepam" thiab indirect anticoagulants).

Lub simultaneous siv lansoprazole slows tus pH-dependent haum ntawm cov tshuaj, teej tug mus rau cov pab pawg ntawm tsis muaj zog acids. Tsis tas li ntawd xam tau tias yog medicament accelerates haum ntawm cov tshuaj uas yog lub hauv paus pab pawg.

"Lantsid" tiv thaiv haum "ketoconazole" hlau ntsev "Ampicillin" thiab "Digoxin".

Lansoprazole los ntawm 10% thiaj li muaj cov clearance ntawm "theophylline".

Sucralfate thiaj li bioavailability ntawm lansoprazole ntawm 30%. Nyob rau hauv no kev twb kev txuas, nws yog qhov tseem ceeb mus soj ntsuam cov luv ntawm kev txais tos ntawm hais tias txhais tau tias (30-40 feeb).

Lansoprazole yog sib xws nrog "Indomethacin", "ibuprofen", "diazepam", "warfarin", "Propranolol" qhov ncauj contraceptives, raws li zoo raws li "prednisone" thiab "Phenytoin".

Antacids yuav tsum tau muab 60 feeb ua ntej los yog 2 teev tom qab thawj coj "Lantsida" vim hais tias lawv ho qeeb thiab txo qhov haum ntawm lub yav tas.

tej tswv yim pom zoo

Ua ntej thiab tom qab txoj kev kho nrog "Lantsid" yuav tsum tau endoscopic tswj ntawm tus neeg mob tus mob. Qhov no yog tsim nyog los kav tawm cancer txoj kev loj hlob, raws li kev kho mob tej zaum yuav npog cov tsos mob ntawm tus kab mob thiab ncua lub tseeb mob.

Nqe thiab analogues

Yuav ua li cas npaum li cas yog cov "Lantsid" capsule? lawv cov nqi yog hais txog 200 rubles. qhov cuab tam yuav hloov lwm yam tshuaj yog tias tsim nyog. Ua li no, xa mus rau ib tug gastroenterologist.

Analogues ntawm cov tshuaj nyob rau hauv kev saib xyuas yog cov "Akrilanz", "Lansoprazole", "Gelikor", "Lanzaptor", "Lanzap", "Lanzabel", "Loenzar-Sanovel", "Lansofed", "Epicurus".

Xyuas

Feem ntau cov neeg mob teb rau "Lantsid" tshuaj (analogs ntawm cov tshuaj tau hais saum toj no) tsuas yog nyob rau qhov zoo sab. Tau txais kev pab hais tias tom qab ib tug ob peb hnub ntawm kev kho mob tsis kaj lub siab tsos mob ntawm peptic rwj kab mob tam sim ntawd ploj. Ntxiv mus, nyob rau hauv ua ke nrog nrog lwm yam tshuaj lub cuab tam txhawb sai kho erosions thiab ulceration rau lub mucosa ntawm txoj hnyuv.

Qhov tsis zoo ntawm cov tshuaj no muaj xws li ib tug loj tus naj npawb ntawm cov nyom tshua. Thaum saib tag nrho cov uas yuav tsum tau ntawm ib tug kws kho mob ntawm lawv cov tsos yuav zam tau.