"Lomfloks": cov lus qhia rau kev siv, nqe, analogs

Yog vim li cas xws li ib tug yeeb tshuaj raws li "Lomfloks" yuav raug muab tso? qhia rau kev siv thiab contra-indications rau lub txais tos ntawm cov tshuaj yuav tsum tau muab nthuav rau hauv kom meej nyob rau hauv no tsab xov xwm. Nyob rau hauv tas li ntawd, los ntawm nws koj yuav kawm txog cov tshuaj no yog muaj nyob rau, uas tshuaj yog ib feem ntawm nws, yuav ua li cas npaum li cas nws cov nqi thiab seb nws analogs nyob rau hauv tej daim ntawv.

Ntim yeeb tshuaj, nws zoo lawm, kev piav qhia thiab muaj pes tsawg leeg

Nyob rau hauv dab tsi daim ntawv xws li ib tug yeeb tshuaj yog muaj raws li "Lomfloks"? Cov lus qhia rau kev siv qhia hais tias tus active medicament yog marketed xwb nyob rau hauv daim ntawv ntawm cov loj cov ntsiav tshuaj (zaj duab xis) oblong ntsiav tshuaj (400 mg) raws li ib lub teeb xim av xim.

Ua lub caij ntawm lub cuab tam yog lomefloxacin (siv raws li tus hydrochloride). Nrog kev xav txog ntxiv Cheebtsam, ces lawv muaj xws li lactose, purified talc, starch, crospovidone, polyvinylpyrrolidone, sodium lauryl sulfate, propylene glycol, magnesium stearate, sodium cov hmoov txhuv nplej glycolate thiab colloidal silicon dioxide.

Muaj pes tsawg leeg ntawm lub plhaub ua raws li nram no tshuaj: methylene chloride, isopropanol, titanium dioxide thiab hydroxypropyl methylcellulose.

"Lomfloks" yog ntsiav tshuaj nyob rau hauv cov hlwv (5 daim) yog muab tso rau hauv cov duab los qhia thawv.

Raws li cov tshuaj ua hauj lwm zoo?

Yuav ua li cas yog cov tshuaj "Lomfloks"? Cov lus qhia rau kev siv qhia hais tias qhov no neeg sawv cev yog ib tug hluavtaws antimicrobial neeg sawv cev. Nws belongs rau lub fluoroquinolone pab pawg neeg ntawm cov tshuaj thiab muaj ib tug dav spectrum ntawm bactericidal kev txiav txim.

Xam tias yog ib tug yeeb tshuaj muaj peev xwm ntawm thaiv cov hlab DNA gyrase kab mob, li no txoj kev ua ib tetramer nrog nws complex thiab puas tabkaum replication thiab transcription ntawm DNA. Raws li ib tug ntawm xws li raug tus kab mob muaj yog ib tug kev puas tsuaj ntawm pathogenic hlwb.

Qhov no medicament yog active tiv thaiv kab tsis zoo thiab, thiab Gram zoo microorganisms thiab aerobes. Ntxiv mus, cov tshuaj nyhuv dejnum rau Chlamydia, Mycobacterium tuberculosis (intra- thiab extracellularly nyob), raws li zoo li ib co hom uroplazmy thiab mycoplasma.

Nyob rau hauv ib tug acidic puag ncig cov tshuaj miv nyuas siv zug yog significantly txo, thiab kuj muaj heev maj mam.

Cov tshuaj muaj ib tug qhia cov nyhuv postantibioticski.

Peb kuj yuav tsum nco ntsoov tias cov streptococci thiab anaerobes yog resistant mus rau lub kev txiav txim ntawm lomefloxacin.

tshuaj

Yuav ua li cas ntev yuav cov tshuaj absorbed "Lomfloks" (ntsiav tshuaj)? Tus neeg siv daim ntawv thov hais tias tom qab cov thawj coj los mus rau hauv nws cov active tivthaiv yog yuav luag tag absorbed los ntawm lub digestive ib ntsuj av.

Los ntawm kev siv 400 mg ntawm lub formulation nws siab tshaj plaws nyob rau hauv concentration cov ntshav cai tom qab 1.5-2 lub sij hawm thiab yog hais txog 3,2-5,2 mg ib liter. Nws yuav tsum tau muab sau tseg tias thaum uas tau txais medicament nyob rau hauv hais tias ntau npaum lomefloxacin ntau tej zaum yuav ntau tshaj lub MIC rau feem ntau cov kab mob. Tsawg kawg yog rau ib nrab ib hnub twg.

Kev sib txuas lus active tshuaj rau ntshav cov nqaijrog yog kwv yees li 10%. Lomefloksatsin haum sai sai penetrates mus rau hauv tag nrho cov ntaub so ntswg ntawm lub cev. Lub concentration ntawm kev siv yeeb tshuaj nyob rau hauv lom kua nruab nrog cev 3-6 lub sij hawm siab tshaj nyob rau hauv ntshav, tshwj xeeb yog nyob rau hauv prostate ntaub so ntswg, mob ntsws macrophages thiab zis.

Lub ib nrab neej ntawm lub active caij yog kwv yees li 7-9 teev. Kwv yees li 70-80% ntawm cov lomefloxacin yog tso zis thaum lub sij hawm lub hnub (nyob rau hauv unmodified daim ntawv no) nyob rau hauv cov zis.

Nyob rau hauv cov neeg mob uas impaired raum muaj nuj nqi ib nrab-lub neej ntawm lub active caij ntawm lub nce ho.

zaj lus tim khawv

Uas kab mob prescribers "Lomfloks"? Cov lus qhia rau kev siv muaj cov nram qab no indications:

• ua pa kab mob (cov kab), los yog es, lawv txo kev sib cais (xws li exacerbation ntawm tus kab mob hlab ntsws thiab mob ntsws muaj dej);
• kab thiab inflammatory kab mob uas yuav muaj tau tshwm sim los ntawm cov kab mob rhiab rau lomefloxacin;
• otitis xov xwm;
• mob thiab mob chlamydial, gonococcal kab mob thiab mixed;
• nyuab thiab uncomplicated kab mob ntawm lub urinary thiab deev systems;
• kis kab mob ntawm nqaij mos mos thiab tawv nqaij;
• cholecystitis thiab enterocolitis kab;
• kab mob ntawm cov pob qij txha thiab cov pob txha, xws li mob osteomyelitis;
• pulmonary tuberculosis (xws li mob hnyav ntaub ntawv ntawm tus kab mob, tshuaj resistant cov kab mob, rifampicin intolerance, concomitant tuberculosis nonspecific inflammatory dab).

Tsis tas li ntawd nco ntsoov tias qhov suav hais tias cov tshuaj feem ntau kws kho rau cov kev tiv thaiv ntawm cov kab mob nyob rau hauv phais transurethral cov txheej txheem.

Contraindications

Yog hais tias muaj yog kev txawv txav nyob rau hauv txhua rooj plaub yuav tsis tau cov ntsiav tshuaj "Lomfloks"? Cov lus qhia rau kev siv (tus nqi ntawm cov tshuaj yog qhia tawm rau hauv qab no) muaj cov nram qab no daim ntawv teev cov contraindications:

• thaum lub sij hawm hnub thiab kev pub niam mis;
• qaug dabpeg, cerebral arteriosclerosis, raws li zoo raws li lub xeev, nrog convulsions;
• Cov me nyuam mus txog hnub nyoog 15 xyoo;
• tus neeg mob meem kev txhawj xeeb rau lomefloxacin thiab lwm yam quinolones.

Medicament "Lomfloks": cov lus qhia rau kev siv

Hauj lwm ntawm qhov cuab tam yog yeej ib txwm muaj nyob rau hauv daim ntawv cov lus qhia. Nyob rau hauv tas li ntawd, lub annotation mus rau yeeb tshuaj qhia rau cov neeg mob hais txog dab tsi koob tshuaj yuav tsum tau noj ib tug muab sib txawv.

Ntsiav tshuaj "Lomfloks" yuav tsum haus (haus dej nyob chav tsev kub). Nws cov hauj lwm zoo tsis yog nyob ntawm seb cov zaub mov kom tsawg. Lub ib txwm ntau npaum ntawm no formulation yog 400 mg ib zaug ib hnub twg.

Thaum tsis hnov raum muaj nuj nqi nyob rau hauv thawj hnub ntawm kev kho mob yog cov tshuaj 400 mg ntawm yeeb tshuaj, thiab tom ntej no - 200 mg (ib zaug ib hnub twg). Cov tshuaj thiab ntev ntawm txoj kev kho yog nyob ntawm seb heev ntawm uas twb muaj lawm sib txawv thiab nyhav.

Nyob rau hauv cov kev tshwm sim hais tias ib tug neeg mob mob TB tshuaj "Lomfloks" yuav tsum tau ua ke nrog tshuaj xws li "Isoniazid", "pyrazinamide" thiab "Ethambutol".

Nyob rau tib lub sij hawm yog tsis tshua muaj undesirable coj lomefloxacin thiab rifampicin. Qhov no yog vim lub fact tias cov tshuaj yog sib tw antagonists.

Risk ntawm photochemical tshua yuav tsum tau significantly txo los ntawm kev noj tshuaj 'Lomfloks "nyob rau hauv rau yav tsaus ntuj.

tshuaj cov kev sib tshuam

Kuv noj lwm yam tshuaj tshuaj "Lomfloks"? Cov lus qhia rau kev siv (txhais tau tias ntawm analogues yuav tsum tau nthuav tawm nyob rau thaum xaus ntawm qhov tsab xov xwm) hais tias cov tshuaj yog peev xwm ua rau cov kev ua ntawm qhov ncauj anticoagulants, raws li zoo raws li yuav ua tau kom lub toxicity ntawm narcotics yuav muab.

Antacids thiab sucralfate qeeb haum ntawm cov tshuaj thiab txo nws bioavailability, txoj kev ua ib tug chelate compound. Nrog kev xav txog cov simultaneous txais tos nrog probenecid, nws muaj txhawb rau inhibition ntawm lub raum feem.

phiv

Tau ib tug tsis zoo feem nyob rau tib neeg lub cev tshuaj "Lomfloks"? Cov lus qhia rau kev siv (xyuas, analogs nyob rau hauv no tsab xov xwm) hais tias ntshai neeg sawv cev muaj cov nram qab no tshwm sim tsis zoo:

• Hlab ntsha thiab lub siab: Vasculitis thiab kev tsim txom ntawm kev ua hauj lwm cardio-pulmonary system.
• Ua pa system: edema ntawm lub ntsws thiab lub suab.
• Kev tsis haum tshuaj: kev tsis haum tshuaj, photosensitivity, anaphylaxis thiab angioedema.
• Plab zom mov: pseudomembranous mob plab thiab ce ntawm qhov ncauj mucosa.
• Siab: txoj kev loj hlob ntawm tus kab mob siab.
• Mob txeeb: polyuria, interstitial nephritis, urinary tuav thiab lub raum tsis ua hauj lwm.
• Nqaij / lub cev pob txha: tendonitis, ligament rupture, arthralgia thiab myalgia.
• Lub paj hlwb (peripheral thiab central): ntxhov siab vim, ataxia, tsis meej pem, convulsions, kev nyuaj siab, tshee, pw tsis taus, kiv taub hau, puas siab puas ntsws, mob taub hau, hallucinations, qhov muag plooj tsis pom kev, saj perversion, photophobia thiab diplopia.
• Ntawm daim tawv nqaij: hyperpigmentation, exfoliative dermatitis, Stevens-Johnson syndrome thiab epidermal necrolysis.
• Metabolism hauv: Hypoglycemia.
• Ntshav: haemolytic anemia thiab thrombocytopenia.

ceev faj

Uas nta ntawm cov tshuaj yuav tsum tau paub txog cov neeg mob, ua ntej yuav noj "Lomfloks" ntsiav tshuaj? Hauj lwm ntawm cov kev npaj, kev qhia ntawv yuav tsum tau kev nyeem ntawv, raws li tau zoo raws li ib yam ua ntej kev sib tham nrog ib tug tshwj xeeb.

Nyob rau hauv xws li ib tug kab mob, raws li mob npuas paug, lub hloov yog tsis yuav tsum tau noj tsoom fwv. Tab sis qhov no yog tsuas yog hais tias tus ob lub raum ua hauj lwm tsis cuam tshuam.

Thaum lub sij hawm txoj kev kho, tshuaj yog tsim nyog yuav tsum tsis txhob raug tus kab mob rau UV rays.

Antacids, thiab cov vitamins, thiab lwm yam tshuaj mas siv uas muaj txhuas, magnesium thiab hlau, yuav tsum tsis txhob coj ob teev ua ntej thiab ob teev tom qab noj cov tshuaj nyob rau hauv kev saib xyuas.

Puas muaj tus muaj peev xwm mus tsav lub tsheb thiab cov kev tswj ntawm cov tshuaj los ntawm txawv mechanisms, "Lomfloks"? Cov lus qhia rau kev siv (tus nqi ntawm cov khoom no yog teev nyob rau hauv seem hauv qab no) qhia hais tias qhov no lub cuab tam yuav ua rau impaired cov xim thiab heev kiv taub hau. Nyob rau hauv no hais txog, tau ntawm tej kev ua hauj lwm ua ub no yuav tsum tau txiav txim siab tsuas yog tom qab kev ntsuam xyuas ntawm tus neeg mob lub teb rau cov tshuaj.

Analogs "Lomfloks" tshuaj nqi xyuas

nyob rau kev siv ntawm cov nyiaj qhia qhia tau hais nyob rau hauv no tsab xov xwm (kev kawm lub hom phiaj). Raws li rau tus nqi, nws yog tau paub lub caij nyoog nqi xwb nyob rau hauv pharmacies. Feem ntau, qhov nruab nrab mas nws txawv ntawm 500 rubles (5 ntsiav tshuaj).

Yuav ua li cas lwm tus neeg hais txog cov tshuaj "Lomfloks" cov lus qhia rau kev siv? Analogues ntawm cov tshuaj xam tau tias yog nws nyob rau hauv ib co nthuav dav. Raws li nws, qhov no tshuaj tej zaum yuav hloov los ntawm cov hauv qab no tshuaj: "Ksenakvin", "Okatsin", "Lomatsin", "maksakvin", "lomefloxacin", "Lofoks", "lomefloxacin hydrochloride."

Raws li rau lub xyuas, lawv yog zoo rau feem ntau yog ib feem. Cov neeg mob hais tias "Lomfloks" ntsiav tshuaj heev zoo tua kab mob. Txawm li cas los, nws yuav tsum tau muab sau tseg tias ib txhia cov neeg uas coj cov tshuaj no tsis tu ncua kev tsis txaus siab ntawm sab los.