Photodynamic kho nyob rau hauv Oncology: qhov zoo thiab qhov tsis zoo

Cancers yog ib tug ntawm cov thawj qhov chaw ntawm cov pejxeem lub neej no. Nyob rau hauv xyoo tsis ntev los, sharply nce tus naj npawb ntawm cov qog nqaij hlav uas kuaj nyob rau hauv cov neeg mob. Tu siab, lawv tsis muaj kev txwv tsis pub rau cov muaj hnub nyoog - tus kab mob no muaj feem xyuam rau cov laus li zoo raws li spares thiab cov me nyuam.

Nyob rau hauv peb lub sij hawm, siv ntau thiab ntau txoj kev tshiab ntawm kev kho mob cancer, cov tshuaj tau nce nyob rau hauv no hais txog no twb yog ua ntej. Ib tug xws li txoj kev yog photodynamic kho nyob rau hauv Oncology. Nrog rau qhov no txoj kev, peb yuav kawm ib tug me ntsis ntau nyob rau hauv no tsab xov xwm.

Lub tswvyim ntawm photodynamic txoj kev kho

Qhov no txoj kev ntawm kev kho mob yog cov abbreviated lub npe ntawm PDT thiab nws cov essence yog siv ntawm lub teeb thiab tej pab pawg ntawm cov tshuaj uas yog hu ua photosensitizers. Thaum raug mus rau lub teeb lub tshuaj tshuaj sau nyob rau hauv mob nqaij pib hlav pib deleteriously cuam tshuam nws lub hlwb.

Nyob rau hauv lub chaw ntawm cov qog, cov kev npaj yuav tsum muab mus rau hauv cov ntshav los yog ua ntawv thov rau ntawm daim tawv nqaij. Tom qab ib tug luv luv lub sij hawm ntawm lub sij hawm nws yog absorbed ntaub so ntswg, thiab ces nyob rau hauv no zajlus qhia beam ntawm lub teeb.

Cia peb kawm dab tsi yog nws biophysics. Photodynamic kho nyob rau hauv Oncology tom qab lub teeb beam ntog yog txo mus rau tshuaj lom neeg kev sis raug zoo nrog cov pa, thiab raws li ib tug tshwm sim, lub mob hlwb raug tua. Yog hais tias xws txoj kev kho yog tsim nyog los tshem tawm cov me me cov hlab ntsha, depriving lub qog noj.

Cov qib PD txoj kev kho

Photodynamic kho nyob rau hauv Oncology muaj xws li ob peb kauj ruam:

1. Introduction sensitizing tshuaj intravenously.
2. Lub tsub zuj zuj ntawm cov tshuaj nyob rau hauv cov nqaij cuam tshuam los ntawm cancer. Muab ntau yam ntawm ntaub so ntswg thiab cov tshuaj, cov kauj ruam no yog tej zaum kav ob peb hnub. Nws yog nyob rau ntawm lub sij hawm no, cov kws txawj thiaj paub hais tias ib tug mob nyob rau hauv lub hauv paus ntawm cov neeg kawm ntawv ntawm concentration ntawm lub sensitizer.
3. Kauj ruam mob irradiation nrog laser beams. Yog hais tias lub cancer yog heev sib sib zog nqus, lub beams siv rau qhov tus me nyuam ntawm LED raj. Nyob rau hauv tus ntawm lub laser pib ib tug tshuaj lom cov tshuaj tiv thaiv, uas tau nyob rau hauv lub hlwb mob cancer tuag, thaum nyob ib sab noj qab nyob zoo nqaij yog tsis cuam tshuam.
4. Kauj ruam lwj cancer cov ntaub so ntswg kho thiab raug hloov. Duration yog hais txog ib lub hlis.

Raws li siv photodynamic kho nyob rau hauv Oncology

Qhov no hom ntawm txoj kev kho yog ho txhim kho qhov zoo ntawm lub neej ntawm mob mob. PDT twb tsis muaj sij hawm ntev tsis zoo ces, tab sis tsis raws li lug siv nyob rau hauv tag nrho cov teb chaws.

Photodynamic Therapy nyob rau hauv Oncology nyob rau hauv Moscow siv txij li thaum 1998. Tam sim no, nyob rau hauv lub capital muaj 5 chaw ua hauj lwm, uas nqa tawm kev ua no. Hais txog 2 txhiab. Cov neeg mob tau kho los ntawm cov qauv no.

Lub Cancer soj ntsuam dispensary №1 tau tsim thiab siv cov hu PDT. Laser irradiation yog ua nyob rau hauv xws li ib tug yam enables mus nce lub qhov tob ntawm allergic ntawm lub rays mus rau 2 cm.

Qhov zoo ntawm no txoj kev ntawm kev kho mob

PDT - ib lub txoj kev ntawm combating cancer thiab precancerous formations. Tam sim no nyob rau hauv thaum ntxov ua sawv ntawm nws Oncology sim siv raws li photodynamic kho nyob rau hauv Oncology muaj ib tug lossis loj kom zoo dua:

• Nws yog ua tau rau muaj kev cuam tshuam tsuas mob hlwb.
• Cov neeg mob yuav tau yooj yim zam lub txheej txheem ntawm txhua hnub nyoog.
• Therapy muaj ib tug maj mam ntxim rau cov hauv nruab nrog cev thiab cov nqaij mos cuam tshuam los ntawm cancer.
• Nyob rau hauv mob cancer ntawm daim tawv nqaij txoj kev muab 100% zoo tau.

• Lub tsev me nyuam mob cancer, cov qauv no yog qhov zoo tshaj, raws li nws tso cai rau koj mus cawm ib tug poj niam lub tsev me nyuam system.
• Kev kho mob yuav tsum tau ua nyob rau hauv ib tug pw hauv paus.
• yuav reapplied yog tias tsim nyog.
• Nws twb tsis muaj mauj teeb meem.
• Siv tus qauv no, nws yog tau tawm hlav nyob rau hauv ib qho nyuaj mus cuag qhov chaw.
• Thaum lub sij hawm txoj kev tus neeg mob yog meej pem.
• Cov qauv no yog kiag li tsis mob.
• Photodynamic kho nyob rau hauv Oncology yuav siv tau raws li ib qho kev ywj txoj kev ntawm kev kho mob, thiab raws li ib feem ntawm kev ua ke nrog txoj kev kho.

Cov kev muaj tug los nyob rau hauv kev mob hlwb, raws li zoo li virucidal (tau puas tib neeg papilloma virus), fungicidal, bactericidal thiab immunomodulatory. Lub xub ntiag ntawm xws li ib tug loj tus naj npawb ntawm zoo ua rau nws nrov.

Cov kev txwv

Dhau li ntau cov kev pab, txoj kev nws muaj nws drawbacks:

• Therapy yog tas rau cov kev nkag tau ntawm lub teeb. Qhov ntawd yog amenable rau kev kho mob yog qhov uas yog nyob ncaj qha nyob rau hauv daim tawv nqaij. Vim li no, nws yog tsis yooj yim sua rau siv txoj kev uas yuav tau tshem ntawm cancer hlwb, uas tau tswm nyob rau hauv yuav luag tag nrho cov nruab nrog cev thiab cov nqaij.
• Tom qab ib tug thaum photosensitizers muab khaws cia tseg rhiab heev mus rau lub teeb.

Tiam sis tag nrho cov saum toj no kuj qhia tau hais tias lub photodynamic kho nyob rau hauv Oncology muaj ib tug heev me flaws.

Indications rau siv tus qauv

Nws yuav tsum tau muab sau tseg hais tias PDT yog siv tsis tsuas yog rau cov tau txais tshem ntawm mob hlav, tab sis kuj rau cov kev kho mob ntawm psoriasis, vitiligo, cutaneous lupus thiab lwm yam kab mob. Photodynamic txoj kev kho yog siv rau cov pov tseg ntawm ntau yam ntaub ntawv ntawm mob cancer thiab precancer txoj kev kho. Nws yog zoo nyob rau hauv lub qhov muag cov kab mob thiab dermatological teeb meem.

Ntxiv mus, siv tus qauv no muab kev kho mob uas tsis yog-kho qhov txhab thiab trophic ulcers.

Leej twg tsis piv txwv ntawm txoj kev PDT

Photodynamic kho nyob rau hauv Oncology muaj contraindications, tab sis muaj hnub nyoog. Nws yog tsis nqa tawm:

• yog hais tias muaj pathology ntawm lub raum thiab lub siab;
• decompensated kab mob ntawm cov hlab plawv system;
• ntawm ntev rhiab heev mus rau yeeb tshuaj;
• ntshav kab mob.

Cov qauv no yog txhob thaum lub sij hawm nyuam thiab lactation.

Photodynamic kho nyob rau hauv Oncology yuav tsum tau siv tsuas yog tom qab kev noj kev haus ib tug kws kho mob, yuav tsum tau txheeb xyuas tag nrho cov uas twb muaj lawm contraindications.

Cov kev npaj siv nyob rau hauv txoj kev kho

Rau nqa tawm no txoj kev kho mob oncologists siv cov tshuaj uas muaj peev xwm yuav muab faib ua ob pawg:

1. thawj tiam sensitizers, nrog porphyrins.
2. thib ob-tiam photosensitizers.

Txawm li cas los ntawm cov pab pawg neeg, mus rau ib tug yeeb tshuaj raug tshwj xeeb uas yuav tsum tau:

• Nws muaj cov cuab yeej rau mloog zoo nyob rau hauv loj tus xov tooj nyob rau hauv cancer thiab nws tsis txeem mus rau hauv cov ntaub so ntswg noj qab nyob zoo;
• tom qab tus txheej txheem sai tas los rau ntawm lub cev thiab muaj ib tug tsis tshua muaj toxicity;
• Nws tsis noog nyob rau hauv daim tawv nqaij;
• Nws yog resistant rau cia thiab tswj mus rau hauv cov hlab ntsha;
• Nws muaj fluorescent zog.

Txheej txheem cej luam ntawm cov tshuaj rau PDT

Ib tug qauv ntawm cov photodynamic kho nyob rau hauv Oncology yog feem ntau siv nrog "Photofrin" tshuaj. Nws yog tshuab txais los ntawm lub xim liab. Thiab siv nws nyob rau hauv cov kev kho mob ntawm cov nram qab no tej yam kev mob:

• Cancers ntawm lub suab. Tom qab ntawm txoj kev tus neeg mob hnov zoo dua, tshwj xeeb tshaj yog qhia txog kev siv cov yeeb tshuaj, thaum cov qog nce mus txog ib tug loj yuav luag thaiv cov hlab txoj suab, thiab laser kho tsis tau tiv nrog nws.
• Barrett tus txoj hlab nqos mov. Lub tshuaj no yog siv raws li ib tug tiv thaiv kev kho mob kom tiv thaiv tau cancer txoj kev loj hlob.
• mob ntsws cancer.

Aminolivulinovaya acid yog siv nyob rau hauv cov ntaub ntawv ntawm ua tem toob keratosis. Nws yog thov ncaj qha mus rau ntawm daim tawv nqaij thiab yog tshuab txais los ntawm xiav. Yuav tsum muaj ntaub ntawv tsuas yog nyob rau hauv lub ntsej muag thiab lub taub hau.

Muaj lwm yam tshuaj, tab sis lawv yog siv ntau tsawg zaus.

Cov kev kho mob txoj kev siv "Photofrin"

Lub npe medicament yog intravenously txhaj mus rau hauv lub cev. Tau sab hauv, nws pib yuav absorbed tsis tau tsuas yog mob hlwb, tiam sis kuj noj qab nyob zoo rau lub cev. Zoo kawg nkaus noj qab nyob zoo lub hlwb nyob rau hauv ib ob peb hnub mus kiag meej txog cov tshuaj yeeb dej caw, thiab nws yuav nyob twj ywm nyob rau hauv cancer.

Tiam sis yog tias koj tseem yuav ua tau tsis muaj dab tsi, ces tsis muaj dab tsi yuav tshwm sim rau lub qog. Cov tshuaj tiv thaiv pib tsuas yog thaum muaj raug mus rau lub teeb ntawm ib tug tej yam wavelength, mus rau lub hlwb.

Yog hais tias koj xav mus nqa tawm tus txheej txheem rau kev kho mob ntawm lub ntsws cancer, ces qhov no yog ua li cas siv ib tug bronchoscope txeem maximally mus rau hauv lub cov nqaij. Cov kws kho mob rau PDT laser yog siv nrog ib tug me me muaj peev xwm, thiaj li tsis muaj kev kub nyhiab cov ntaub so ntswg yuav tsis tau txais ib yam.

Duration ntawm kev kho mob nyob rau qhov chaw ntawm lub qog thiab nws qhov ntev (feem ntau yog nws yog los ntawm 5 mus rau 45 min). Tuag hlwb thiab cov nqaij mos ploj nyob rau hauv ib tug ob peb hnub. Tom qab soj ntsuam, yog tias yuav tsum tau, ib tug thib ob txoj kev.

Thov tsum paub hais tias txoj kev kho nrog rau cov kev siv ntawm "Photofrin" tsis txhua yam yog tso cai, nws yog txhob yog hais tias muaj yog:

• fistula ntawm cov hlab pas thiab bronchi;
• mob nqaij hlav uas yog faib los ntawm loj cov hlab ntsha;
• plab lub rwj los yog mob leeg;
• kev tsis haum tshuaj mus rau yeeb tshuaj.

Tag nrho cov lus nug tas sib tham nrog koj tus kws kho mob ua ntej rau txoj kev.

Tshwm sim los ntawm PDT

Feem ntau sab nyhuv ntawm tus txheej txheem siv "Photofrin" yog lub zog rhiab heev mus rau lub teeb. Tej zaum ntau yog o ntawm cov kev kho mob qhov chaw thiab ib tug me me ce.

Thaum cov tshuaj nkag mus rau hauv tus kab mob, nws accumulates nyob rau hauv lub hlwb thiab cov nqaij mos nyob rau hauv ib ob peb hnub thiab ob peb lim piam tom qab cov kev kho mob tej zaum yuav nyob twj ywm nyob rau hauv lub hlwb. Tag nrho lub sij hawm no, tus neeg mob lub qhov muag thiab daim tawv nqaij yog nkag mus rau lub teeb. Los ntawm cov teeb kaj lug tiv thaiv tej qhov chaw pib swell thiab sawv hlwv nyob rau hauv ib ob peb feeb.

Qhov no rhiab heev yuav mob ob peb lub hlis, nws tag nrho cov nyob rau tus yam ntxwv ntawm tus kab mob. Peb yuav tau txhua lub sij hawm kom tsis txhob ncaj qha tshav ntuj, tab sis nws tsis txhais hais tias koj xav tau mus zaum nyob rau hauv ib chav tsev tsaus. Dosed nruab hnub nrig pab kev puas tsuaj ntawm tshuaj nyob rau hauv lub hlwb thiab yeej txhawb lawv rov qab.

rhiab heev yuav maj tsis kam, thiab koj yuav nrhiav tau nws tawm, tab sis tsis ntxov tshaj ib lub hlis tom qab photodynamic txoj kev kho.

Lub luag hauj lwm ntawm lwm yam teebmeem yuav ua tau ib tug o ntawm qhov chaw ntawm txoj kev kho. Yog hais tias cov txheej txheem yog nqa tawm nyob rau hauv lub caj pas, cov thawj lub sij hawm yuav muaj teeb meem nqos, thiab tom qab manipulation ntawm lub ntsws - ua pa. Thaum nrhiav kom tau ntawm tej tsos mob yuav tsum urgently nrhiav kev kho mob. Lwm yam kev phiv xws li cov nram qab no:

• xeev siab, ntuav, mob taub hau, nros - yog hais tias PDT twb nqa tawm nyob rau hauv txoj hlab nqos mov;
• ua tsis taus pa, txoj kev loj hlob ntawm ntsws los yog mob ntsws muaj dej - yuav ua tau tom qab lub teeb kev kho mob.

Txhua yam ntaub ntawv yuav tsum qhia rau tus kws kho mob.

Pom zoo tom qab kev kho mob

Koj muaj peev xwm tsis txhob muaj cov teeb meem loj phiv tom qab kev kho mob, yog tias koj paub yuav ua li cas los npaj rau nws thiab mus coj thwj tom qab ntawm txoj kev. Ua li no, ua raws li cov tswv yim pom zoo:

1. Mus rau lub tsev kho mob rau photodynamic txoj kev kho, nws yog tsim nyog los kaw tag nrho cov tsev cov qhov rai thiab yuav kub hnyiab tau, raws li tau zoo raws li saib mus rau nws hais tias cov teeb ntxoov tau muaj kev tiv thaiv los yog lwm yam.
2. Siv sij hawm nrog koj mus rau lub tsev kho mob tas looj tsom iav dub, ib lub kaus mom (dua li wide-brimmed lub kaus mom) los tiv thaiv lub ntsej muag. Ris tsho yuav tsum muaj npab ntev, thiab nyob rau nws ob txhais taw - ris thiab nkawm thom khwm (nyob rau hauv xws li ib tug teeb meem no, kev cia siab ntawm tshuaj pleev thaiv hnub yog me me).
3. Tom qab ntawm txoj kev, nyob rau hauv 30 hnub, nws yog advisable tsis mus tshwm sim nyob rau hauv txoj kev nyob nrab hnub, thiab nco ntsoov tiv thaiv koj cov tawv nqaij txawm nyob rau cov pos huab hnub thaum koj tawm.
4. Tag nrho cov ceev thiab thaum muaj xwm ceev mob, nws yog ntshaw kom hloov mus rau yav tsaus ntuj.
5. Tsev nyeem ntawv yog tsim nyog los tiv thaiv lub qhov muag los ntawm ncaj qha lub teeb los ntawm lub teeb.
6. Tom qab zawv plaub siv tsis tau rau tshuab - kub huab cua tej zaum yuav qhib lub substance seem nyob rau hauv lub hlwb thiab ua liab thiab hlawv.

Yog hais tias koj ua raws li tag nrho cov tswv yim pom zoo, lub photodynamic kho nyob rau hauv Oncology yuav qhia cov nyiaj pab ntau tshaj efficiency thiab tus neeg mob yuav muaj kev zoo siab nrog tus raug.

Rov cov

Txhua txoj kev ntawm kev kho mob yuav tsis tau Attendance zoo siv rau cov kev kho mob ntawm tag nrho cov neeg. Tab sis photodynamic kho nyob rau hauv Oncology xyuas yog feem ntau zoo. Cov neeg mob hais tias tom qab cov kev kho mob lawv tus mob markedly zoo, nws yog tshwj xeeb tshaj yog muaj tseeb rau cov qog nqaij hlav ntawm daim tawv nqaij, thiab lwm yam daim tawv nqaij kab mob. Tom qab PDT yog zoo tsis muaj nti, ntawm daim tawv nqaij yuav nqus tsev vacuum.

Cov neeg mob qhia tsis mob kev kho mob, ib tug me me npaum li cas ntawm cov kev phiv. Tab sis nws yuav tsum tau muab sau tseg hais tias yuav luag tag nrho cov neeg mob nrog koj tham txog ib tug nce rhiab heev tom qab cov txheej txheem. Peb yuav tsum tsis txhob ci ci thiab nti tawm tiv thaiv koj ob lub qhov muag thiab tawv nqaij ntawm kev sib cuag nrog nws.

Photodynamic kho nyob rau hauv Oncology muaj negative tswv yim tsuas yog los ntawm cov neeg uas tsis ua raws li tus kws kho mob lub tswv yim thiab tsis nthuav qhia uas twb muaj lawm comorbidities. Nws yuav tsum tau muab sau tseg tias nyob rau hauv cov qog nqaij hlav ntawm lub suab los yog mob ntsws complex txoj kev kho, thiab tom qab nws yuav muaj teeb meem nqos thiab ua tsis taus pa, tab sis nws yog ib tug ib ntus tshwm sim uas yuav maj.

Tom qab kev kho mob, yuav luag tag nrho cov neeg txaus siab rau cov kev tshwm sim, tshwj xeeb tshaj yog yog hais tias tus txheej txheem yog nqa tawm ib tug heev tsim nyog tshwj xeeb. Yog li, photodynamic kho nyob rau hauv Oncology nyob rau hauv Novosibirsk kawm zoo kawg li xibfwb Sergey Danilovich Nikonov. Nws tsim photodynamic txoj kev kho rau lub hlwb, raws li zoo raws li ib tug txoj kev ntawm txoj kev kho kantseromatoznogo pleurisy, nyob rau lub sij hawm no nws tau tso tawm heev heev cov ntaub ntawv thiab kev cov ntaub ntawv.

Nyob rau hauv lwm lub zos, tseem muaj cov chaw kho mob uas paub txhij txhua nyob rau hauv kev kho mob cancer tau piav. Photodynamic kho nyob rau hauv Oncology nyob rau hauv Krasnodar muaj kev soj ntsuam oncologic dispensary №1. Qhov no chaw kho mob yog txawm peem rau nrog qhov tseeb technology, li ntawd, cov neeg mob nyob rau hauv cov kev kho mob zoo tsis tau ua xyem xyav.

Qhov zoo ces, tam sim no txawm li no txaus ntshai tus kab mob, xws li mob cancer, tsis yog ib tug kab lus. Qhov tseem ceeb tshaj - kom qhia tau nws mus rau theem thaum koj yuav ntse tiv nrog nws. Thiab rau tag nrho cov no, ces koj xav kom koj them ntau dua sai sai rau lawv noj qab haus huv thiab yauv tsis tu ncua kho mob kuaj. Saib xyuas ntawm koj tus kheej thiab noj qab nyob zoo!