Analogs thiab cov lus qhia rau kev siv "lomefloxacin"

Yuav ua li cas yuav hloov tau xws li ib tug yeeb tshuaj raws li "lomefloxacin"? Analogs ntawm cov tshuaj, nws cov hom phiaj, thiab cov kev txwv txog kev siv kho thaj chaw yuav sib tham txog hauv qab no. Koj kuj yuav kawm txog yuav ua li cas kom zoo zoo siv qhov cuab tam, thiab nyob rau hauv dab tsi npaum li cas.

Daim ntawv ntawm cov tshuaj, nws ntim, thiab nws tivthaiv qhov chaw

Uas pob yog muaj ntawm cov nyiaj? Qhov uas nws qhia rau hauv daim ntawv thov? "Lomefloxacin" - ib ntsiav tshuaj, muab tso rau hauv lub hlwv thiab fej nyob rau hauv daim ntawv packs, ua ke nrog rau cov lus xaus.

Yuav ua li cas yog cov khoom xyaw nrog cov tshuaj? Lub active ingredient ntawm cov tshuaj yog lomefloxacin hydrochloride. Tsis tas li ntawd nws muaj xws li lwm yam koom haum pab Cheebtsam.

Tus kho thaj chaw ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "lomefloxacin"? Phau ntawv lub xeev hais tias qhov no bactericidal antimicrobial tshuaj uas belongs rau ib pab pawg neeg antibiotikopodobnyh nyiaj, uas yog, fluoroquinolones, thiab nruab nrab yog cov thib ob tiam ntawm cov tshuaj no.

Yuav ua li cas yuav ua rau tus antimicrobial miv nyuas siv zug ntawm cov tshuaj nyob rau hauv kev saib xyuas? Tej zog "lomefloxacin" Ntsiav tshuaj (400 mg) twb tau ua tsaug rau lub fact tias lawv active tshuaj yog muaj peev xwm ntawm ib tug thaiv cov hlab cov nyhuv ntawm DNA gyrase (i.e. kab mob enzyme) uas muab supercoiling. Tsis tas li ntawd, qhov no neeg sawv cev tsim ib tug ruaj khov compound (complex) nrog nws tetramer thiab cuam tshuam DNA transcription thiab replication ntawm cov kab mob hlwb, ua rau lawv tom ntej kev puas tsuaj.

Cov qhia kev ua ntawm lub medicament tshwm kuj tsis zoo aerobic kab mob xws li cov gonococci, Salmonella, Pseudomonas, Haemophilus thiab Escherichia coli, kab mob cholera pathogen, meningococci, Shigella, Morganella thiab thiaj li nyob. Tsis tas li ntawd medicament "lomefloxacin" (400 mg) depressing ntxim rau ib tug Proteus, chlamydia, Campylobacter, mycoplasma, Legionella, ib co pneumococci thiab staphylococci.

Peb tsis tau hais tias tus hais tias cov tshuaj yog zoo heev tiv thaiv Mycobacterium tuberculosis. Nws yog tau txo lub sij yawm ntawm lawv tshem tawm, raws li tau zoo raws li thaum ntxov resorption ntawm muaj infiltrates.

Therapeutic nyhuv "lomefloxacin" cai txawm nyob rau hauv nws cov uas tsis muaj ntau nyob rau hauv cov ntshav. Yog hais tias qhov no kuj yog cai heev tsis tshua muaj.

Kev tig tau muaj peev xwm lam ntsiav tshuaj

Yuav ua li cas absorbed hais tias medicament? Yuav ua li cas nws hais tias nyob rau cov lus qhia rau kev siv? "Lomefloxacin" muaj zoo absorbency. Tom qab tau txais cov tshuaj uas nws ncov ntshav concentration tiav tsis pub dhau 55-85 feeb.

Cov ntshav protein uake mus rau yeeb tshuaj tsuas yog nyob rau 10%. Tsis tas li ntawd, nws muaj nws zoo haum khoom nyob rau hauv ntau yam nruab nrog cev thiab cov nqaij (nrog rau cov genitals, pob qij txha, ua pa paths, ENT kabmob, pelvic kabmob, cov pob txha, plab mog, nqaij mos mos, etc.), qhov chaw uas nws cov ntsiab lus yog 5-7 lub sij hawm ntau dua ntshav.

Nws yuav tsum tau muab sau tseg tias ib txhia ntawm lomefloxacin metabolized thiab ntaub ntawv ob peb derivatives.

Lub sij hawm ntawm feem ntawm cov tshuaj yog 9 teev. Tso zis rau nws ntawm tubular secretion nyob rau hauv cov zis (70-85%) thiab cov quav (25-30%).

Indications rau los ntawm cov txhais tau tias

Ob peb cov neeg paub, tab sis nyob rau hauv lub khw muag tshuaj chains yuav pom tsis tau tsuas yog tshuaj "lomefloxacin", tab sis kuj cov tshuaj "lomefloksatsin + pyrazinamide + ethambutol + Prothionamide + Pyridoxine". Nyob rau hauv cov ntaub ntawv no ob hais tias medicament yog qhia rau kev siv nyob rau hauv:

• kab mob (purulent) daim tawv nqaij thiab nqaij mos (xws li kub nyhiab, mob qhov txhab, thiab lwm yam);
• osteomyelitis;
• chlamydia thiab gonorrhea (nrog rau cov Blepharoconjunctivitis thiab chlamydial conjunctivitis);
• Mob huam mob (e.g., kab mob cholera, kab mob dysentery, typhoid kub taub hau, salmonellosis);
• Ua pa kab mob (xws li mob ntsws, recurrent hom);
• biliary ib ntsuj av tau tus kab mob;
• kab mob nyob rau hauv lub urogenital cheeb tsam (e.g., urethritis, prostatitis, cystitis, pyelonephritis);
• pulmonary tuberculosis (xws li nyob rau hauv kev kho mob ntawm cov neeg uas muaj sai progressing ntaub ntawv ntawm tus kab mob, raws li tau zoo raws li ntau zog kuj mus "Isoniazid" thiab "Rifampicin" thiab nrog tsis kam mus cov kws khomob);
• ua ntej thiab tom qab transurethral phais (tsuas yog rau cov prophylactic hom phiaj).

Bans lub sij hawm ntawm antimicrobial ntsiav tshuaj

Nyob rau hauv tej rooj plaub, koj muaj peev xwm siv tsis tau cov tshuaj nyob rau hauv kev saib xyuas? Yuav ua li cas no qhia phau ntawv qhia? "Lomefloxacin" yog contraindicated rau cov kev siv nyob rau hauv:

• hnub;
• kev pub niam mis;
• tus kheej rhiab heev ntawm cov tshuaj teej tug mus rau lub fluoroquinolone pab pawg neeg;
• raws li hnub nyoog (tejzaum nws inhibition ntawm skeletal txoj kev loj hlob).

Cov lus qhia rau kev siv

"Lomefloxacin" - tshuaj uas tsuas qhia rau haus. Lawv yuav tsum tau noj ib zaug ib hnub twg, tsis hais tus noj mov, haus txog 230 ml ntawm zoo tib yam dej.

Lub caij ntawm kev kho mob nrog rau qhov no tshuaj nyob rau hauv lub mob, raws li tau zoo raws li nyob rau hauv lub heev ntawm tus kab mob thiab rhiab heev ntawm lub pathogen.

Khuav mob ntsws thiab bronchopneumonia txaus kho ntau npaum ntawm 400 mg ntawm cov tshuaj tshaj kaum hnub.

Nyob rau hauv cov kev kho mob ntawm chlamydia (urogenital), xws li kab mob thiab chlamydial, gonococcal thiab chlamydial kab mob, cov neeg mob muab 400-600 mg ntawm yeeb tshuaj ib hnub twg, nrog lub caij ntawm daim ntawv thov rau 28 hnub.

Kev kho mob ntawm rov nyuab mob ntsws thiab mob ntsws hom nqa nyob rau hauv ib tug txhua txhua hnub ntau npaum sib npaug zos rau 400-800 mg ntawm yeeb tshuaj, ob lub lis piam.

Thaum mycoplasma kab mob xam tau tias yog tshuaj tua tau 400-800 mg ib hnub twg, nrog lub caij ntawm thawj coj ntawm lub ntsiav tshuaj nyob rau hauv 3 lub lis piam.

Mob txeeb zig kab mob amenable mus kho 400 mg ntawm cov tshuaj. Nrog rau qhov no kev kho mob ntawm uncomplicated mob ua rau 5 hnub, thiab tham - 14 hnub.

Nyob rau hauv gonorrhea mob tshuaj "lomefloxacin" pom zoo kom coj ib tug ntau npaum ntawm 600 mg. Raws li rau tus mob hauv daim ntawv ntawm tus kab mob no, nws kho mob yog nqa tawm nyob rau hauv thaum uas tig mus nrog tej immunotherapy. Nyob rau hauv cov ntaub ntawv no, muab cov tshuaj nyob rau hauv tib hnub koob tshuaj rau 5 hnub.

Kev kho mob ntawm pulmonary tuberculosis yuav siv sij hawm 14-30 hnub (nyob rau hauv tej rooj plaub mus txog 3 lub hlis). Tej kab mob los kho tus mob tshuaj txhaj koob tshuaj ntawm 200 mg ib hnub ob zaug.

Thaum qhia raum pathologies los yog muaj mob loj tsawv xwm, raws li zoo li cov neeg niaj hemodialysis, "lomefloxacin" yog muab nyob rau hauv ib tug npaum li ntawm 400 mg ib hnub twg, nrog nws cov ntxiv txo rau 200 mg.

Cov tshwm sim ntawm ib tug tsis zoo ua cim

Yuav ua li cas tsis zoo los yuav ua rau yus kev noj tshuaj "lomefloxacin"? Coj cov ntsiab lus raws li nram no cov tshuaj tiv thaiv:

• bronchoconstriction, nce hnoos qeev secretion, xeev siab, hnoos, dysphagia;
• dyspnea, ntuav, ua pa kab mob, raws plab, goiter;
• kab mob khaub thuas zoo li cov tsos mob, dysgeusia, epigastric mob, tsam plab;
• nce ntawm daim siab enzymes, dryness ntawm lub qhov ncauj, hnyuv los ntshav;
• cem quav, arthralgia, plab hlaub tu-sauv, hloov cov lus ntawm cov xim, myalgia;
• pseudomembranous mob plab, mob taub hau, hloov nyob rau hauv qab los noj mov, vasculitis, kiv taub hau;
• insomnia, mis rhiab thiab rov qab, qaug zog, nervousness, ib tug siab ntawm lub tuam malaise, kev nyuaj siab, tshee;
• hyperkinesia, qaug zog, convulsions, hallucinations;
• mob nyob rau hauv lub qhov muag, suab nrov, thiab mob nyob rau hauv lub pob ntseg;
• dysuria, nce arousal, hematuria, paresthesias;
• crystalluria, qhov muag plooj tsis pom kev;
• albuminuria, glomerulonephritis, Leucorrhœa, edema, polyuria, epididymitis, teeb meem tso zis, orchitis, tenesmus;
• cyanosis, anuria, hypotension, vaginitis, tachycardia, arrythmia, perineal mob, bradycardia;
• intermenstrual los ntshav, thrombocytopenia, paum Candidiasis, heart attack myocardial infarction, cardiomyopathy, phlebitis;
• qhov muaj mob ntawm lub plawv tsis ua hauj lwm thiab angina, purpura, cerebrovascular mob, khaus ntawm daim tawv nqaij;
• pulmonary embolism, photosensitivity, ua rau kom fibrinolysis, tawm pob, lymphadenopathy, tawm pob;
• epistaxis, erythema (phem), koj ua daus no, gout, kub flashes;
• superinfection, hypoglycemia, candida, lub nov ntawm nqaij tawv ntawm nqhis dej.

Ib tug overdose ntawm tshuaj

Nrog ib tug overdose ntawm tshuaj "lomefloxacin" neeg kev xeev siab, erosive txhab ntawm txoj hnyuv mucosa, lengthening ntawm QT-lub sij hawm, kiv taub hau, qaug dab peg, feeb tsis meej, raws li zoo li ntau zog phiv tshua.

Vim hais tias hemodialysis overdose txhais tau hais tias pom tau hais tias pab tsis tau txoj kev kho saum toj no tej yam kev mob yog nqa tawm nyob rau hauv lub hauv paus ntawm uas twb muaj lawm cov tsos mob.

Sis nrog lwm yam tshuaj

Nrog ua ke nrog ntawm "lomefloxacin" nrog "theophylline" nws metabolism yuav luag inhibited.

Thaum simultaneous thawj coj ntawm antacids thiab sucralfate yog tsim chelate ceg uas txo lub bioavailability ntawm lomefloxacin. Uas yog vim li cas lub caij nyoog nruab nrab txais tos ntawm hais tias medicaments yuav tsum muaj tsawg kawg yog 4 teev.

Joint siv ntawm "lomefloxacin" thiab siab koob tshuaj caffeine prolongs lub ib nrab-lub neej ntawm lub yav tas.

Nyob rau hauv cov kev kho mob ntawm tuberculosis yuav tsum tsis txhob tau ua nyob rau hauv thaum uas tig mus nrog lub txais tos ntawm cov nyiaj "Rifampicin", txwv tsis pub nws yuav ua rau kev thaiv kev txiav txim.

Tib mus kho mob nrog narcotics yuav muab tsub lub toxicity ntawm cov tshuaj thiab yuav ua rau qaug dab peg.

"Lomefloxacin" muaj peev xwm ua rau kom cov efficiency ntawm anticoagulants rau qhov ncauj thawj coj.

Cov tshuaj, uas yog blockers ntawm tubular secretion, inhibit qhov kev feem ntawm "lomefloxacin".

tej tswv yim pom zoo

Yog hais tias lub raum tus kab mob yuav tsum tau ib tug yuav tsum hloov ntawm koob tshuaj, uas nyob ntawm lub QC metrics.

Tag nrho cov kev kho koj xav tau caiv txhob ntev tus ntawm tej UV teeb qhov chaw, xws li tshav ntuj.

Vitamin tshuaj mas siv muaj xws li ntau yam mineral additives yuav tsum coj 120 feeb tom qab los yog ua ntej qhov suav hais tias tau txais tshuaj.

zoo xws li cov tshuaj

Medicament "lomefloxacin" muaj ntau yam analogues. Lub ntsiab hloov cov tshuaj kws txawj xav txog cov nram qab no: "Abaktal", "Elefloks", "Zanotsin", "TSifran", "Avelox", "Tsiprolet", "Zofloks", "tsiprinol", "Kvintor" "Ciprofloxacin", "Levofloxacin "" tarivid "," Levotek "," pefloksatsina "," Levofloks "," Ofloxacin "," Norbaktin "," Ofloks "," norfloxacin ".

Ntsiav tshuaj "lomefloxacin": xyuas

Thaum kom meej meej pom tias kis neeg sawv cev uas yog nkag siab lub thib ob tiam ntawm fluoroquinolones, raws li zoo raws li qhov tseeb xaiv ntawm medicinal koob tshuaj thiab lub caij nyoog kev kho mob, kev xyuas txog rau tam sim no txhais tau tias yog purely zoo.

Raws li cov nqe lus ntawm cov neeg mob, cov tshuaj no tau muaj pov thawj nws tus kheej raws li ib tug zoo antimicrobial tshuaj uas txaus deals nrog rau ntau yam pathological microorganisms. Txawm li cas los, ib co neeg siv hais tias cov tshuaj no tej zaum kuj ua rau txoj kev loj hlob ntawm tej yam kev phiv, tab sis raws li ib tug txoj cai, lawv muaj mob-txhais nyob rau hauv cov xwm los yog lawv tus kheej tam sim ntawd tom qab qhov kawg ntawm txoj kev kho.