"Atorvastatin": xyuas, analogs, muaj pes tsawg leeg thiab cov lus qhia rau kev siv

Cov feem ntau hom tshuaj tsim los txo cov theem ntawm tag nrho cov roj uas txhaws taus thiab LDL yog cov "Atorvastatin". Testimonials txog nws tsis meej xwm, txawm hais tias tus zoo tshaj ntawm cov khoom no yog paub tseeb hais tias los ntawm kev tshawb fawb. Nyob rau tib lub sij hawm cov tshuaj muaj tsuas yog ib full-fledged competitor - "Rosuvastatin" (thiab nws cov Generics). Vim hais tias nws yog cuab kev tias lub "atorvastatin" npaj neeg mob testimonials tej zaum yuav tsis muab lub hom phiaj cov lus qhia. Yog li ntawd, los soj ntsuam nws cov teebmeem yuav tsum tau ncauj lus kom ntxaws tsom xam ntawm lub mechanism ntawm qhov kev txiav txim thiab cov kev cai ntawm daim ntawv qhia rau kev siv.

Mauj tshuaj tshuaj characterization

Atorvastatin belongs rau lub pharmacological chav kawm ntawv ntawm statins peb tiam. Los ntawm inhibiting lub enzyme lub luag hauj lwm rau lub endogenous synthesis ntawm cov roj uas txhaws, thiaj li tus nqi ntawm cov atherogenic lipoprotein feem. Tsawg-density feem (LDL) yuav txhim khu deposition ntawm cov roj cholesterol thiab ua tiv thaiv kab mob cov lus teb nyob rau hauv lub endothelium, vim uas tus tsim cov quav hniav.

Ib yam li lwm statins, atorvastatin ho thiaj li tus nqi ntawm cov LDL, thiab yog li ntawd ho slows txoj kev loj hlob ntawm cov quav hniav. Nyob rau hauv no ib txwm mus rau nws involution yog tsis pom, thiab lub lub cheeb ntawm ib tug coronary artery (los yog lwm yam atherosclerotic), tseem zoo li qub. Cov kev soj ntsuam cov nyhuv - tseg cia txoj kev loj hlob ntawm coronary mob plawv, cerebrovascular los yog mob arterial insufficiency lub sab nqua.

"Atorvastatin": indications rau kev siv

Ua ntej kev yuav tsum txhais tau cov indications rau kev siv ntawm cov tshuaj. Lawv muab tau los ntawm cov yooj yim mechanism ntawm qhov kev txiav txim thiab yog txuam nrog ib tug roj uas txhaws taus-txos nyhuv. Ntau yam indications:

• raws roj ntsha (familial) hypercholesterolemia, heterozygous;
• polygenic (thawj) hypercholesterolemia chav kawm ntawv IIa raws li Fredrickson;
• Thaum lawv tseem (IIb) dyslipidemia;
• Homozygous familial hypercholesterolemia;
• hypertriglyceridemia (kev kho mob nrog statin nyob rau hauv ua ke nrog nrog kev noj haus thiab kev qoj ib ce);
• tej yam kev mob txuam nrog atherosclerotic vascular txhab ntawm lub plawv phab ntsa, lub hlwb, ob lub raum, extremities;
• tawg nrog ib tug high school cov mob plawv;
• cov kev tiv thaiv ntawm mob coronary txheej xwm tiv thaiv lub keeb kwm yav dhau ntawm uas twb muaj lawm atherosclerotic txhab ntawm lub coronary hlab ntsha;
• kev tiv thaiv ntawm myocardial infarction re-los yog cerebral mob stroke.

Cov readings txiav txim seb tus neeg mob thaum nws yuav tsum tau lub sij hawm ntawm "Atorvastatin" tshuaj. Cov kws kho mob hais txog nws daim ntawv thov kom meej meej paub meej tias qhov no yuav tsum tau. Nws yog ib tug pov thawj tseeb hais tias statins, xws li "Atorvastatin" nrog nws heev heev Generics yog npaum li cas nyob xeeb dua qub kardioform acetylsalicylic acid, txawm hais tias piv pab txo tau qhov yuav tsim thawj myocardial infarction thiab rov mob.

tshuaj analogues

Tag nrho cov ntsiav tshuaj "Atorvastatin", uas xyuas yuav tsum tau nyeem hauv qab no, ua los ntawm txawv kws tuam txhab uas muag. Feem ntau cov feem ntau, cov npe ntawm cov tshuaj yog muab hloov, uas tso cai rau lawv yuav tsum tau patented. Trade npe analogues, uas yog, cov tshuaj uas muaj atorvastatin li cov active tivthaiv, cov nram qab no: "Anvistat" thiab "Atokord", "Atomas" thiab "Ator", "Atorvoks" thiab "Atoris", "Vazotor" thiab "Lipoford" "Lipitor" thiab "Liptonorm", "Novostat" thiab "Torvazin", "Torvakard" thiab "Tulip".

Tsis tas li ntawd, ib co manufacturers tsim lawv cov tshuaj "Atorvastatin" (koj muaj peev xwm nyeem tau cov xyuas hauv qab no) nyob rau hauv tib luam lub npe. "Actavis", "Vertex", "Izvarino Pharma", "ALSI Pharma", "Canon Pharma" Obolentsenskoe kws lub tuam txhab, "Protek-SVM", "North Star", Tabuk Pharmaceuticals, TEVA Kws Industries, thiab lwm leej lwm tus tsim ib tug yeeb tshuaj lub npe uas muaj txog cov INN ( "atorvastatin") thiab cov tshuaj consoles. Ib qho piv txwv yog "Atorvastatin Teva", xyuas uas paub meej tias nws soj ntsuam hauj lwm zoo.

qauv

Txuas mus rau lub tshuaj 'atorvastatin cov lus qhia rau kev siv, kev xyuas thiab kev soj ntsuam raws li kev cai tsis muaj ntaub ntawv hais txog qhov sib txawv ntawm cov tshuaj cov ntaub ntawv. Nyob rau hauv kev xyaum, xws txawv tsis nyob ua ib ke, thiab lawv tswj lub zog ntawm cov tshuaj txiav txim. Yuav ua li cas yog ib qho tseem ceeb yog yuav ua li cas sai sai los lub kho nyhuv ntawm cov tshuaj. Uas yog vim li cas lub formulation "Lipitor" yog cov kev siv ntawm tus thawj yeeb tshuaj.

Cov tshuaj daim ntawv muaj atorvastatin calcium ntsiav tshuaj thiab plhaub. Cov yav tas, nyob rau hauv lem, muaj calcium carbonate, microcrystalline cellulose, lactose monohydrate, polysorbate 80, sodium croscarmellose, magnesium stearate, hydroxypropylcellulose, talc, titanium dioxide, polyethylene glycol, hydroxypropylcellulose, simetikonovoy emulsion, benzoic thiab sorbic acid.

Txuas mus rau tus thawj tshuaj "Atorvastatin" phau ntawv qhia (xyuas kuj nyob rau hauv no taw tes) tsis muaj ntaub ntawv hais txog tus luj ntawm txhua tivthaiv. Qhov no yog ib tug coj mus muag pub leejtwg ntawm lub American lub tuam txhab Pfizer HCP Corporation. Xws li ib tug ntau npaum daim ntawv "Lipitor" tso cai rau peb mus cuag ib tug qhov concentration ntawm atorvastatin nyob rau hauv cov ntshav.

Ua ke daim ntawv "atorvastatin"

Nyob rau hauv kev npaj "Atorvastatin" nqi (tus neeg mob testimonials paub meej tias nws) yog mus siv cuag mus rau ib tug ntau yam ntawm cov neeg mob. Nws yog ib tug kuj zoo tshuaj uas muaj peev xwm yuav ua ke nrog rau lwm cov chav kawm ntawm cov tshuaj. Feem ntau cov feem ntau, "atorvastatin" thiab lwm yam statins yog ua nyob rau hauv kev rho tawm, uas yog, nyob rau hauv ib ntsiav tshuaj no tsuas yog ib yam kom nquag plias khoom sib ua zaub mov. Txawm li cas los, muaj neej coj cov ntaub ntawv.

Piv txwv li nram qab no tshuaj: "Kaduet", "Duplekor", "statins". Ntawm no, "atorvastatin" yog ua ke nrog amlodipine, ib tug calcium channel blocker, uas yog feem ntau kuj siv nyob rau hauv cov kev kho mob ntawm mob mob. Cov tshuaj ntawm cov tshuaj yog xaiv tus kws kho mob.

Standard ntau npaum "atorvastatin"

Tshuaj "Atorvastatin", indications, ua tim khawv thiab cov tswv yim nyob rau hauv lub soj ntsuam kev siv uas peb xav txog nyob rau hauv peb kev saib xyuas, yog muaj nyob rau hauv peb tus qauv noj tshuaj npaum cas: 10, 40 thiab 20 mg. Ib tug ua ke npaj "Kaduet" muaj 10 mg ntawm atorvastatin thiab amlodipine 5. "Statins" yog ua nyob rau hauv ob hom: 10/5 thiab 10 / 10mg. Nyob rau hauv kev npaj "Duplekor" 4 ntau npaum ntawm atorvastatin thiab amlodipine: 10/5, 10/10, 20/5, 20/10 mg. Qhov no thiaj li tus naj npawb ntawm cov ntsiav tshuaj rau cov neeg mob uas muaj rau siv thiab statins thiab calcium channel blockers rau cov kev kho mob ntawm cov kab mob. Qhov no yog tiav thiab ib tug txo nyob rau hauv tus nqi ntawm kev kho mob.

Xaiv cim "atorvastatin"

Thawj txhais tau tias muaj atorvastatin ntes tau nyob rau hauv lub qhov muag yog "Lipitor". Qhov no yog cov thawj cov tshuaj, uas nqa tawm cov kev ntsuam xyuas. Tom qab ntawd muaj kuj yog lwm yam tshuaj nyob rau hauv lwm lub npe. Sau npe yuav tsum tau tsuas muaj ib txoj kev qhia txog cov bioequivalence "Lipitor." Thaum lub caij, nws yuav khav ntawm ib tug ob peb manufacturers. Yog li ntawd, tau txais ib tug kws kho mob muab tshuaj rau cov uas twb muaj lawm tshuaj "Atorvastatin" analogues ntawm cov kev txheeb xyuas yuav tsum tau kawm kom zoo zoo.

Feem ntau, tus kws kho mob pom zoo kom ib tug tshuaj uas muaj proven bioequivalence "Lipitor" thiab muaj cov nyhuv piav nyob rau hauv daim ntawv cov lus qhia. Tus nqi ntawm cov "Lipitor" yog muaj, nws tsis yog nyuaj kom tau nws rau ib tug kho. Txawm li cas los, nws tsis yog tshuaj rau cov neeg mob uas twb muaj lawm tej chaw vim kev xiam oob qhab ntau tus kab mob. Nyob rau hauv cov ntaub ntawv no, cov neeg tshuaj uas tej zaum yuav muab concessional tswj los ntawm lub Center rau xeem thiab kev ntsuam xyuas nyob rau hauv cov tshuaj. Lawv cov hauj lwm zoo kuj yog muaj pov thawj.

Testimonials txog qhov "atorvastatin"

Nyob rau hauv kev npaj "Atorvastatin" saib xyuas tej neeg mob yuav tsis muaj peev xwm, vim hais tias tsis muaj kev ntsuag lipid profile yog tsis tau mus txiav txim rau cov los ntawm cov tshuaj. Yog li ntawd, nyob rau hauv thiaj li yuav xyuas kom meej efficiency, nws yuav tsum txheeb xyuas cov kev hloov ntawm lipid fractions. Ntxiv mus, tej yam "Atorvastatin", xyuas uas muaj nyob rau hauv loj qhov ntau, muab cov lus qhia txog kev phiv tshuaj. Cov feem ntau yog tsis haum los. Toxicity yog tsawg tsawg thiab feem ntau imperceptible. Txawm li cas los, nyob rau hauv txhua rooj plaub cov tsos ntawm cytolysis syndrome thiab nyob rau hauv transaminases txoj hlua peb nce yuav tsum tau tshem tawm ntawm cov tshuaj.

Cov neeg mob hais tias cov tshuaj lom los tsis tshua muaj. Vim li no, muaj ntau yam cov neeg mob yuav tsum tau mus tshuaj uas yus paub los yog cov txheeb ze, txawm hais tias tus lo lus uas peb yuav tsum tau kev kho mob sib tham, soj ntsuam thiab kev txiav txim ntawm cov zauv feem ntawm cov ntshav lipids. Nyob rau hauv tas li ntawd, muaj ntau yam tshuaj li lawm thiab muab zog, piv txwv li, hais tias nws yog tau txo lub cev hnyav.

Tab sis ib tug los ze zog saib qhov yuav tsum tau muaj ib tug kuj "Atorvastatin" tshuaj xyuas. Slimming nws yog tsis haum, thiab muaj peev xwm tsuas yog muab nyob rau hauv ua ke nrog loads thiab kev noj haus. Ua ke siv "atorvastatin" thiab lwm yam lipid tej kab mob, raws li yog feem ntau pom zoo rau cov neeg tsis muaj kev kho mob cov kev kawm, ua rau rhabdomyolysis thiab siab toxicity.

Xyuas ntawm cov kws kho mob txog cov tshuaj

Nyob rau hauv kev npaj "Atorvastatin" saib xyuas tus kws kho mob tseem ceeb tshaj tus neeg mob xyuas. Tib yam siv rau lwm yam tshuaj. Nyob rau hauv dav dav, lub xyuas tag nrho cov abstracts kws txawj tuab cov tshuaj txoj kev nyab xeeb thiab zoo heev. Nws thiaj li tag nrho cov roj uas txhaws taus thiab LDL, thaum ntau zuj zus HDL. Qhov no yog tsis tshua muaj ib qho tseem ceeb vim hais tias nws tso cai rau koj los tswj txoj kev loj hlob ntawm atherosclerotic cov quav hniav, thiab ncua lub qhov pib ntawm myocardial infarction.

Dynamics hypocholesterolemic nyhuv nyob rau hauv cov kev npaj "Atorvastatin" (ib tug saib xyuas ntawm txhua tus kws kho mob qhia nws) yog heev Schedule. Normalization ntawm ntshiab lipid profile yog tiav tsis pub dhau 1.5-2 lub hlis. Lub "rosuvastatin" yog tiav tsis pub dhau 30-50 hnub. Txawm li cas los, thaum lub sij hawm "atorvastatin" ntau soj ntsuam cov kev tshawb fawb los pab txhawb nws cov hauj lwm zoo thiab kev ruaj ntseg. Nyob rau hauv Feem ntau, cov no yog cov ob tug zoo tshuaj, txhua tus uas yuav muab siv rau cov kev kho mob ntawm hypercholesterolemia thiab prophylaxis ntawm lub plawv cov kab mob.

Tus nqi ntawm cov tshuaj

Cov tshuaj "Atorvastatin" nqi (ntau txheeb xyuas txog qhov no svidelstvo) sib txawv nyob ntawm lub chaw tsim tshuaj paus. Lub kim tshaj plaws yog ib tug "Lipitor" - tus thawj yeeb tshuaj. Hlis kev kho mob nqi yog 900-1100 rubles thaum tau txais ib koob tshuaj ntawm 40 mg. Thaum ib tug txhua txhua hnub ntau npaum ntawm 20 mg kev kho mob nqi yog 800-900 rubles. Generic "Lipitor" yog cheaper npaum li.

Tus nqi ntawm cov kev kho mob nrog hli "Atoris 40 mg" 500 rubles, thaum uas tau txais 20 mg - 200 rubles. Lub "Atoris" - yog bioequivalent "Lipitor" tshuaj, siab hloov nws. Tseem muaj cheaper tshuaj, "Torvakard" "Lipitor", "Torvas" nqi ntawm txhua lub hlis kev kho mob nyob rau hauv ib tug txhua txhua hnub koob tshuaj ntawm 40 mg rau 300 rubles cheaper. Thiab tus nqi ntawm kev kho mob nrog ib tug txhua txhua hnub koob tshuaj ntawm 20 mg yuav 100-150 rubles.