Clostridia nyob rau hauv cov quav nyob rau hauv ib tug me nyuam ntawd txhais li cas?

Clostridium - lawv yog cov neeg sawv cev ntawm lub cev plab hnyuv muaj ntawm tus txiv neej. Lawv feem ntau nyob rau hauv txoj hnyuv loj, tiam sis yuav tsum kuaj nyob rau hauv ib co lwm qhov chaw ntawm lub digestive system, raws li zoo raws li nyob rau hauv lub qhov chaw mos huam thiab nyob rau hauv daim tawv nqaij.

Yuav ua li cas yog Clostridium?

Clostridium - ib tug kab-zoo kab mob. Lawv paim ib qho enzyme uas yog muab kev koom tes nyob rau hauv lub cleavage ntawm cov protein rau hauv amino acids. "Clostridia" los ntawm Greek txhais hais tias "ntxaiv". Qhov no lub npe yog vim lawv npaug txheej txheem (nyob rau hauv lub sij hawm no, cov kab mob ua thicker nyob rau hauv lub central feem thiab tapered rau hauv lub xaus).

Number of clostridia, uas yog ib feem ntawm ib tug noj qab nyob zoo hnyuv muaj kev hloov. Lawv tus xov tooj yog nyob rau hauv lub hnub nyoog ntawm cov me nyuam. Nyob rau hauv cov me nyuam mus txog ib lub xyoo yog lub cai ntawm 1000 CFU ib tug kab, nyob rau hauv cov me nyuam laus tshaj ib xyoo - tus nqi ntawm mus txog 100 000. Tag nrho cov no yog coj mus rau hauv tus account nyob rau hauv lub sij hawm ntawm tus mob.

Qhov ntau txaus ntshai clostridium?

Klostridiozy - ib tug mob kis tus kab mob, uas muaj feem xyuam rau tib neeg thiab tsiaj. Clostridia ua txaus ntshai kab mob xws li pseudomembranous mob plab, tshuaj tua kab mob raws plab, botulism, roj gangrene, tetanus, raug tshuaj lom thiab necrotic enteritis. Pathogenic cov kab mob cuam tshuam vim qhov kev tso tawm ntawm toxins A thiab B thiab cov protein, depressing lub plab hnyuv contraction.

Pseudomembranous mob plab thiab tshuaj tua kab mob-mob raws plab, kab mob tshwm sim mas nyob rau hauv lub tsev kho mob. Qhov no yog vim lub fact tias nyob rau hauv lub tsev kho mob siv ntau yam ntawm tshuaj tua kab mob thiab disinfectants, uas txhawb nqa lub tsim ntawm kab mob uas yog resistant rau disinfectants. Tsis tas li ntawd, kev noj tshuaj tua kab mob yog ib tug pab tau rau qhov tshwm sim ntawm clostridia thiab ua rau kom lawv tus xov tooj. Thaum lub sij hawm kev kho mob nrog rau cov tshuaj tsis tau tsuas yog ua kom puas pathogenic cov kab mob plab, tab sis kuj suffers ncaj qha nws microflora.

Yog hais tias pom clostridia nyob rau hauv cov quav nyob rau hauv ib tug me nyuam, cov niam txiv yuav tsis tau sound lub tswb. Nws yuav tsum tau nco ntsoov hais tias hais tias cov kab mob no sawv cev ntawm ib tug noj qab nyob zoo plab hnyuv microflora yog muab kev koom tes nyob rau hauv lub cleavage ntawm cov protein thiab nkoos peristalsis. Tab sis nyob rau hauv thiaj li yuav tsis txhob muaj cov kev loj hlob ntawm cov kab mob loj heev, koj yuav tsum tau kom khiav ntawm lawv tus xov tooj, uas yog tu ncua kev tshawb nrhiav.

Ua rau klostridioza

Lub genus Clostridium muaj ntau tshaj 100 yam, uas yog muab faib ua 5 pab pawg. Feem ntau ntawm lawv yog cov tsis txaus ntshai rau tib neeg. Clostridia nyob rau hauv cov hnyuv ntawm cov tib neeg thiab tej tsiaj txhu. Nrog quav kab mob nkag tau rau hauv lub hauv av, qhov uas lawv muaj peev xwm nyob tau ib lub sij hawm ntev nyob rau hauv daim ntawv ntawm cov noob, raws li lawv muaj peev xwm yuav nrhiav tau nyob rau hauv cov dej. Klostridioza qhov chaw yog tsiaj txhu thiab tibneeg.

Cov kis tau tus mob txoj kev - fecal-oral. txoj kev ntawm kab mob - hu-tsev (los ntawm cov tais diav, cov khoom ua si, khaub ncaws thiab ob txhais tes). Qhov ua rau ntawm clostridial kab mob yog ib tug ua txhaum ntawm cov kev cai ntawm tus kheej kev tu cev.

Uas feem xyuam rau nyob tus yeees ntawm plab hnyuv microflora?

Yam rau cov plab hnyuv microflora raug muab faib ua sab nraud thiab sab hauv.

Sab nrauv:

• cov ib puag ncig tej yam kev mob nyob rau qhov chaw ntawm mus tas li qhov chaw nyob;

• heev kev nyuaj siab;

• xwm ntawm mov (clostridia nyob rau hauv cov quav muaj nyob rau hauv tus me nyuam, yog hais tias tus me nyuam thaum ntxov pauv mus rau dag noj, muaj zog los ntawm kev noj zaub mov uas muaj ib tug ntev lub txee lub neej ntawm txoj kev pheej hmoo ntawm kev tsim neeg laus klostridioza);

• Siv tshuaj tua kab mob, cov tshuaj hormones thiab immunosuppressive tshuaj.

domestic:

• tsis muaj zog tiv thaiv cov lus teb ntawm tus kab mob;

• hlwb ruamqauj (postnatal hypoxia);

• kev coj li hluas ntawm lub hauv paus poob siab system;

• prematurity;

• kab mob ntawm lub plab hnyuv nosocomial kab mob;

• pw tsaug zog teeb;

• phais;

• mob ua pa kab mob.

Clostridia: Cov tsos mob

Antibiotikodissotsiirovannye raws plab tsim tsis tsuas vim hais tias ntawm clostridia. Yog tseem pathogens Salmonella, Candida, Staphylococcus aureus, Klebsiella. Qhov no hom ntawm kev zawv plab yog lub txiaj ntsim ntawm nosocomial kab mob. Tab sis cov me nyuam mos yog tsis raug rau tus kab mob no, vim hais tias niam cov kua mis lawv tau ib tug loj tus naj npawb ntawm tiv thaiv kab mob yam tseem ceeb uas inhibit qhov kev loj hlob ntawm cov clostridia.

Antibiotikodissotsiirovannye raws plab yuav nqa txawv tsos mob los ntawm me me mus rau mob loj heev raws plab, pseudomembranous mob plab, uas nyob rau hauv lub qhaj ntawv ntawm kev kho mob nyob rau hauv 30% ntawm cov neeg ua rau yus tuag.

Pseudomembranous mob plab muaj nyob rau hauv lub 4-10-th hnub txij thaum lub caij pib ntawm tshuaj tua kab mob kev kho mob. Lub ntsiab mob:

• tsiag ntawv los ntawm mob pib;

• lub cev kub ntawm lub nce saum toj no 39,5 ° C;

• tsam plab;

• sharply txo qab los noj mov;

• poob phaus tshwm sim;

• sai pib qhia tej yam tshwm sim mob intoxication;

• Kev ntswj mob plab;

• pheej rov qab ua ntuav;

• palpation neeg mob pom tau tias plob tsis so tswj mob;

• quav tshaj, nyias, dej, ntsuab nrog putrid tsis hnov tsw;

• tam sim no nyob rau hauv cov quav hnoos qeev, cov ntshav thiab scraps ntawm fibrinous overlaps.

Enteritis - yog lub feem ntau me me kab mob, uas feem ntau yog xaus li tsis muaj teeb meem. Symptomatology ntawm tus kab mob muaj tsis muaj ib yam nta.

Necrotic enteritis yog txiav txim los ntawm lub tsim ntawm ulcers thiab erosions, rhuav tseg mucosa. cov tsos mob:

• Lub rov tshwm sim ntawm hemorrhagic necrosis chaw thaum pib ntawm lub me me hnyuv;

• hemorrhagic chaw nyob rau hauv liab;

• muaj yog narrowing nyob rau hauv lawv cov quav o;

• tus neeg mob ua daus no, muaj ib tug kub taub hau;

• ntuav;

• frothy ntshav raws plab.

Clostridia nyob rau hauv cov me nyuam mos ua mob loj heev ntaub ntawv ntawm tus kab mob. Klostridioz tshwj xeeb txaus ntshai rau ntxov ntxov cov me nyuam mos. cov tsos mob:

Tseem Ceeb • ntse deterioration ntawm tus me nyuam;

• sai ntiav ua tsis taus pa;

• ua tej yam tshwm sim ntawm toxicity thiab exsicosis;

• tsis muaj kev qoj ib ce;

• ua ib ce tuag ileus.

Nyob rau hauv cov me nyuam mos, ntxov ntxov cov me nyuam mos raws li ib tug tshwm sim ntawm tus kab mob yog feem ntau yuav tshaj cov me nyuam hlob, tsim plob tsis so tswj kev puas tsuaj thiab peritonitis. Nyob rau hauv feem ntau tus neeg mob, klostrodioz cov me nyuam mos yog neeg tuag taus.

Thaum nws yog tsim nyog los soj ntsuam cov hnyuv muaj?

• heev plab hnyuv mob yog tsis kho tau.

• Clostridium nyob rau hauv cov quav ntawm ib tug me nyuam yuav ua tau, yog tias tam sim no nyob rau hauv cov quav hnoos qeev, pieces ntawm undigested zaub mov; sis tsis ncaj coloring ntawm ib lub rooj zaum.

• ruaj tsis khov lub rooj zaum.

• flatulence thiab plab hnyuv tu-sauv, uas yog tsis amenable rau kev kho mob.

• anemia, rickets.

• Atopic dermatitis nrog cov ntsiab ntawm cov theem nrab kab mob.

• Nquag mob ua pa kab mob.

• Sepsis.

mob klostridiozov

Mob klostridioza tshwm sim los ntawm cov nram qab no nta (ib tug keeb kwm ntawm tus neeg mob):

• siab daim ntawv cog lus txoj kev loj hlob ntawm tus kab mob nrog rau cov kev txais tos ntawm antibacterial npaj;

• Nyob rau hauv feem ntau tus neeg mob, tus kab mob no muaj feem xyuam rau cov me nyuam yaus;

• klostridioz yog yus muaj los ntawm mob pib;

• kub taub hau;

• yam ntxwv cov tsos mob ntawm kev mob loj intoxication;

• cov tsos mob ntawm plab.

Kuaj mob:

• clostridia nyob rau hauv cov quav nyob rau hauv ib tug me nyuam pom los ntawm bacteriological xeem (cov qoob loo nyob rau hauv cov xim kab lis kev cai nruab nrab):

• taw los ntawm lub endoscopy;

• Nyob rau hauv tej rooj plaub, qhia tau hais tias ib tug me ntawm lub qog ua kua membrane;

• CT luam theej duab los mus txiav txim hauv lub xub ntiag ntawm edema thiab thooj ntawm cov nyuv phab ntsa.

Clostridia: kev kho mob

Ua ntej txoj kev kho klostridiozov tseem ceeb kom tsis txhob noj tshuaj tua kab mob.

Yog hais tias ib tug me nyuam tau pom clostridia, kev kho mob yuav tsum tau los noj qab nyob zoo plab hnyuv microflora. Rau cov hom phiaj, muab tshuaj "Bifidumbacterin", "Lactobacterin", "Bifikol", "Hilak-forte", "Linex" thiab lwm tus neeg.

Feem ntau cov pab pawg Clostridia yog nkag mus rau lub xov xwm "vancomycin" "Metronidazole". Rau hauv loj heev ntaub ntawv ntawm tus kab mob neeg mob Txoj kev lis ntshav txoj kev kho yog ua los tsis tau ntawm lub cev.

Nyob rau hauv txhua tus neeg mob, cov kev kho mob ntawm clostridia nyob rau hauv cov me nyuam thiab cov laus muaj xws li eubiotics, enzyme npaj ( "Mezim-forte", "Omez" thiab al.), Vitamins (B pab pawg neeg) thiab chelators ( "Polisorb", "Smecta", "Enterosgel "thiab al.).

Kev tiv thaiv klostridioza

Lub ntsiab tiv thaiv kev ntsuas los pab tsis txhob muaj kab mob clostridia, yog ua raws li cov kev tu cev qauv: kev ntxuav tes (tom qab ib tug taug kev, ua ntej noj mov, tom qab mus rau pej xeem qhov chaw), ntxuav thiab scalding ntawm txiv hmab txiv ntoo thiab zaub ua ntej noj, heev thaum tshav kub kub kev kho mob cov khoom. Nyob rau hauv tas li ntawd, qhov yuav tsum tau rau lossi muaj ib tug noj qab nyob zoo plab hnyuv muaj thiab lub cev. Tseem ceeb: Txoj kev siv cov tshuaj tua kab mob yuav tsum tau pib tsuas yog tom qab ib tug kws kho mob tshuaj.