Cov tshuaj "Citalopram": xyuas ntawm cov kws kho mob

Yuav ua li cas zoo tshuaj xws li "citalopram"? Xyuas ntawm cov kws kho mob hais txog qhov no lam khoom xam tau tias yog nyob rau hauv cov ntaub ntawv ntawm qhov tsab xov xwm. Tsis tas li ntawd, nws muab ntaub ntawv hais txog dab tsi ua rau kev phiv, hais tias txhais tau hais tias, yuav ua li cas rau kev nws kom txais tos ntawm dab tsi pharmacodynamic zog nws muaj.

Muaj pes tsawg leeg, hauj lwm ntawm cov tshuaj, nws zoo thiab cov

Nyob rau hauv dab tsi tau daim ntawv yuav tshuaj "Citalopram"? Testimonials hais tias lub tsev muag tshuaj saw yog ib lub cuab tam muag nyob rau hauv cov ntsiav tshuaj daim ntawv lenticular thiab yeej zoo lawm, them nrog ib tug dawb zaj duab xis txheej. Tus ntoo khaub lig sectional tshuaj no muaj ib tug me ntsis yellowish puab txheej.

Yuav ua li cas yuav muab "Citalopram" tshuaj? Cov lus qhia, xyuas tau qhia hais tias cov active ingredient ntawm cov tshuaj yog ib yam khoom uas ntawm lub tib lub npe - citalopram, uas yog nyob rau hauv daim ntawv ntawm cov hydrobromide. Nrog kev xav txog cov koom haum pab Cheebtsam, yog siv raws li microcrystalline cellulose, pregelatinized starch, thiab magnesium stearate.

Nws yuav tsum raug sau tseg hais tias qhov no zaj duab xis txheej neeg sawv cev uas muaj polyvinyl cawv, Opadry II, macrogol, talc thiab titanium dioxide.

Nyob rau hauv lub muag khoom ntshai cov tshuaj nkag mus rau hauv contour hlwb ua los ntawm PVC los yog txhuas, uas yog fej nyob rau hauv ib lub thawv uas ua los ntawm cov duab los qhia.

Pharmacodynamic yam ntxwv ntawm antidepressant

Yuav ua li cas yog cov tshuaj "Citalopram"? Xyuas hais tias qhov no yog ib qho kev nyuaj siab. Nws mechanism ntawm qhov kev txiav txim yog txuam nrog hluav ntawm (xim) serotonin reuptake kho kom haum xeeb tam sim no nyob rau hauv lub synapses ntawm lub paj hlwb, raws li zoo raws li tsawg heev ntxim rau cov reuptake ntawm neurotransmitters dopamine thiab norepinephrine. Nws yuav tsum tau muab sau tseg tias lub cuab tam tsis muaj lub peev xwm los hnov mob nrog ib tug ntau yam ntawm receptors (nrog ib co serotonin, dopamine, H1-histamine, adrenoceptors, m-cholinergic receptors, GABA receptors thiab benzodiazepine receptors).

Peb tsis tau hais tias cov tshuaj "citalopram", xyuas uas muaj li nram no, nws yuav pab los txhim kho tus neeg mob lub mus ob peb vas, suppresses ntxhov siab vim, thiaj li ntxhov siab vim, kev nyuaj siab, eliminates dysphoria, thiab relieves compulsive. Nyob rau hauv tas li ntawd, nws yuav luag yeej tsis ua kom ib tug soporific nyhuv.

Raws li cov kws txawj, ib tug ruaj khov nyhuv ntawm cov tshuaj no cai tom qab 7-10 hnub tom qab tas mus li siv.

Kev tig tau muaj peev xwm medicament

Yuav ua li cas yog cov yam ntxwv ntawm cov tshuaj ntawm cov tshuaj "Citalopram"? Teb qhia hais tias nws cov ncov concentration ntawm active tshuaj nyob rau hauv cov ntshav no tshwm sim tsis pub dhau plaub teev tom qab haus. Cov kev hloov nyob rau hauv nws qib yog linear.

Lub bioavailability ntawm cov tshuaj txuas 80%, thiab cov ntawv cog lus rau ntshav cov nqaijrog yog 79%.

Nyob rau hauv cov ntshav ntawm citalopram yog tam sim no nyob rau hauv nws thawj daim ntawv. Qhov no tshuaj yog hloov los ntawm oxidation, demethylation thiab deamination. Lub ib nrab-lub neej ntawm no tivthaiv yog 1.5 hnub. Nws twb evacuated nrog cov zis thiab los ntawm cov plab hnyuv ib ntsuj av.

Indications antidepressant tshuaj

Yog vim li cas peb yuav tsum tau ib lub cuab tam xws li "citalopram"? Xyuas ntawm cov kws kho mob hais tias cov tshuaj no yog muaj los txais tos nyob rau hauv:

• panic teeb meem;
• depressive lub sijhawm uas nws mob heev thiab moderate.

Nws yuav tsum tau muab sau tseg tias muab cov tshuaj no yuav tsum tsuas muaj ib txog tej kev.

Contraindications yeeb los

Nyob rau hauv dab tsi tej yam kev mob yuav tsis siv cov tshuaj "Citalopram"?

Xyuas qhia cov nram qab no contraindications rau kev siv cov tshuaj no:

• me neeg mob lub hnub nyoog (raws li cov phau ntawv, cov kev nyab xeeb thiab ua tau ntawm cov ntsiav tshuaj nyob rau hauv lub hnub nyoog no tsis tau tsim);
• High rhiab heev ntawm tus neeg mob yuav citalopram, raws li zoo raws li ib yam ntawm cov nws pab tshuaj;
• thaum uas tau txais nrog inhibitors ntawm monoamine oxidase xws li moclobemide, selegiline, linezolid (tsis pub dhau ob lub lim piam tom qab discontinuation ntawm lawv thawj coj);
• thaum noj tshuaj QT prolonging lub sij hawm ntawm lub ECG (s xws li pimozide) thiab congenital lengthening ntawm lub luv).

Antidepressant "Citalopram": cov lus qhia rau kev siv

Guest cov kws txawj hais lus cam uas saib xyuas yuav tsum tau muab cov tshuaj, nyob ntawm seb tus neeg mob tus mob. "Citalopram" coj lus ib zaug ib hnub twg. Yog li cov ntsiav tshuaj tsis chewed thiab ntxuav nrog ib tug me me npaum li cas ntawm cov kua.

Cov tshuaj no yuav siv tau rau txhua lub sij hawm ntawm lub hnub tsis hais txog ntawm cov pluas noj (dua li nyob rau tib lub sij hawm).

Thaum muaj kev nyuaj siab txoj kev kho pib nrog tau txais 20 mg ib hnub twg. Nyob ntawm seb tus neeg mob tus kheej tshua ua zoo raws li lub heev ntawm kev nyuaj siab, ntau npaum yuav muab ntau zog rau lub siab tshaj plaws, i.e. mus txog 40 mg ib hnub twg.

Raws li nrog rau ceeb tsis meej yuav tsum tau coj cov tshuaj "Citalopram"? Xyuas cov neeg mob hais tias nyob rau hauv rooj plaub no tus active tshuaj yog muab nyob rau hauv ib koob tshuaj ntawm 10 mg ib hnub twg (rau 1 lub lim tiam), thiab ces nws yuav muaj zog mus rau 20 mg ib hnub twg. Yog li, txhua hnub koob tshuaj ntawm cov tshuaj yuav yog nyob ntawm seb koj tus kheej tus neeg mob cov lus teb. Tom qab lub saum toj no tus nqi ntawm cov tshuaj yuav tau nce mus 40 mg ib hnub twg.

Cov neeg laus dua 65 xyoo ntawm "Citalopram" hnub nyoog tshuaj nyob rau hauv ib koob tshuaj ntawm 10 mg. Nyob rau hauv lub heev ntawm kev nyuaj siab thiab tus neeg teb, tej zaum nws yuav muab tau ntau zog rau ib tug tshaj plaws ntawm 20 mg ib hnub twg.

Thaum tsis hnov raum muaj nuj nqi, nrog rau mob raum tsis ua hauj lwm ntawm ntsis xwm thiab heev ntawm cov uas qaug zog, cov kev hloov ntawm txoj kev lub dosing regimen yog yuav tsum tau. Rau cov neeg uas muaj mob loj raum insufficiency xwm yuav tsum tau kev pab tshwj xeeb nyob rau hauv cov kev xaiv ntawm ib tug kho koob tshuaj.

Thaum tsis hnov lub siab muaj nuj nqi, nrog rau hepatic tsis ua hauj lwm muaj mob loj tsawv thiab me me, cov thawj ntau npaum ntawm cov tshuaj yog 10 mg txhua txhua hnub (rau cov thawj 2 lub lis piam). Nyob ntawm seb tus kheej tshua, nws muaj peev xwm muab tau ntau zog mus rau 20 mg. Cov neeg uas mob loj heev hepatic insufficiency xwm yuav tsum tau kev pab tshwj xeeb nyob rau hauv koob tshuaj xaiv.

Cov neeg uas muaj ib tug uas tsis muaj kev ua si ntawm lub isoenzymes li CYP2C19, ib tug thawj zaug ntau npaum yog 10 mg ib hnub twg (2 lub lim tiam). Nyob ntawm seb tus neeg teb, nws muaj peev xwm muab tau ntau zog mus rau 20 mg.

Raws li cov lus qhia, cov kho nyhuv tom qab thawj coj ntawm ib tug kawm antidepressant yog twb khees tom qab 2-4 lub lis piam. Nyob rau hauv cov ntaub ntawv no, lub caij ntawm ib lub chav kawm ntawm txoj kev kho yog txiav txim los ntawm tus mob ntawm tus neeg mob thiab tolerability ntawm cov kev kho mob. Feem ntau, cov tshuaj yog pom zoo kom siv li 6 lub hlis.

Ncua tseg medicament

Yuav ua li cas cov neeg no hais txog dab tsi tshua tshwm sim nyob rau ib tug ntse nres noj tshuaj, "Citalopram" xyuas? Leej twg coj qhov cuab tam, nws hais tias cov tsos mob tshwm sim tom qab cia li tas txoj kev siv cov tshuaj no yog tsis raug. Feem ntau cov feem ntau, cov neeg mob qhia me ntsis kiv taub hau, xeev siab, qaug zog, mob taub hau, insomnia, paresthesia, nervousness, ntuav thiab tshee.

Yog li, thaum lub kawm tiav ntawm kev kho mob los ntawm lub cuab tam yuav tsum tshem nws maj mam, li ob peb lub lis piam. Qhov no yuav tso cai rau cov neeg mob yuav tsum tsis txhob tshem cov tsos mob. Raws li ib tug txoj cai, nws yog txaus rau ob lub lis piam, txawm hais tias nyob rau hauv txhua rooj plaub rau lo lus nug yuav tsum tau txiav txim siab los ntawm ib tug kws kho mob rau ib tug neeg zus. Yog li ntawd, rau ib txhia neeg tej zaum nws yuav siv sij hawm 3 lub hlis los yog ntau tshaj.

Phiv tshua tom qab noj antidepressant

Yuav ua li cas hom kev tshua yuav tsum tau paub txog qhov tsis zoo ua cim los ntawm cov neeg mob, ua ntej yuav noj cov tshuaj "Citalopram"? Xyuas txog tej kev phiv los hais tias, raws li nyob rau hauv cov ntaub ntawv ntawm kev siv ntawm lwm yam tshuaj SSRI, nyob rau hauv keeb kwm yav dhau ntawm "Citalopram" neeg mob kuj cai undesirable los. Txawm li cas los, nws yuav tsum tau muab sau tseg tias tag nrho cov ntawm lawv yog cov muaj zog heev thiab yog nraum.

Feem ntau, phiv cov txheej xwm nram qab no thawj coj ntawm ib tug kawm tshuaj cai thaum lub sij hawm thawj 2 lub lim piam ntawm txoj kev kho. Nyob rau tib lub sij hawm lawv muaj ntau weaker nrog kev txhim kho ntawm tus neeg mob tus mob.

Yog li ntawd, "Citalopram" yuav ua rau kev phiv xws li:

• High rhiab heev, ntxhov siab, anaphylactic tshua, mob taub hau, ntxhov siab vim, depersonalization, tsis libido, amnesia;
• aggression, ua txhaum ntawm orgasm nyob rau hauv cov poj niam, mania, coj txawv txawv kev npau suav, ntxhov siab vim, suicidal xav, tsis meej pem, kiv taub hau;
• nkees nkees, tshee, impaired concentration, ntxhov siab, hallucinations, convulsions;
• zoo siab, extrapyramidal teeb meem, migraine, hemorrhage, nce libido;
• xeev siab, gynecological los ntshav, paresthesia, ntuav, palpitations, serotonin syndrome, ntshai tsam, pw tsis taus, bruxism, tsam plab, nkees, raws plab;

• akathisia, hnyuv los ntshav, kub siab, qhov ncauj qhuav, tachycardia, dyspnea, cem quav, bradycardia, mob plab, hnoos;
• ringing nyob rau hauv lub pob ntseg, kab mob siab, orthostatic hypotension, rhinitis, saj ntxaug, txo cov ntshav siab, pom tau qhov sib cuam tshuam, arrhythmia, ejaculation teeb meem, sinusitis, disturbance ntawm kev pab, galactorrhea, kev sib deev kawg, tsis qab los noj mov, hyponatraemia;
• poob phaus, polyuria, nce qab los noj mov, nqaij doog, tsis txaus secretion ntawm ADH, kev hloov nyob rau hauv lub electrocardiogram, daim tawv nqaij ua pob liab vog, alopecia, koj qhov hnyav nce, angioneurotic edema, hypokalemia, mob tso zis heev, khaus;
• photosensitivity, nce tawm hws, kev raug mob ntawm kev raug mob thiab pob txha lov, urticaria, pyrexia, purpura, myalgias, yawning, arthralgia thiab lwm tus neeg.

Mob ntawm tshuaj overdose

Tshuaj "citalopram", analogues ntawm uas muaj li nram no, yuav ua rau cov nram qab no cov tsos mob ntawm overdose: tshee, convulsions, ntuav, tachycardia, nkees nkees, dilated cov menyuam kawm ntawv, bradycardia, hypotonia, los yog tawg, xeev siab, tawv nqaij cyanosis, serotonin syndrome, nras ceg thaiv, ntxhov siab , kiv taub hau, mob insufficiency, stupor, hyperventilation, tawm hws, ventricular arrhythmia, atrial arrhythmia, coma.

tshuaj cov kev sib tshuam

Xam tias yog ib tug txhais tau tias ntawm haum zoo nrog lwm yam tshuaj. Yog li ntawd, nws co-thawj coj yog txhob nrog cov nram qab no cov neeg ua hauj:

• Mao inhibitors (tej zaum yuav tsim kev phiv loj heev, xws li serotonin syndrome).
• Tshuaj cas sim haum lub sij hawm QT (yuav ua rau muaj kev cuam tshuam ntawm lub plawv atherosclerosis, uas thaum kawg yuav raug kev tuag).
• "Pimozide" (tejzaum nws lengthening QT luv).

Nws yuav tsum tau muab sau tseg tias cov pa roj carbon monoxide-thawj coj "Citalopram" nrog rau lwm cov tshuaj yuav txo tau qhov qaug dab peg chaw pib. Nyob rau hauv tas li ntawd, cov tshuaj no yog tsis ntshaw kom muab nrog serotonergic agents, cov tshuaj uas muaj St. John lub wort wort, indirect anticoagulants, "warfarin", haus dej cawv, desipramine.

zoo xws li cov tshuaj

Yuav ua li cas yog xam tau tias yog analogues tshuaj? Uas yog zoo dua? "Citalopram"? Xyuas hais tias cov tshuaj yuav tsum tau hloov los ntawm cov hauv qab no tshuaj: "Paxil", "cytological" "Pram", "Sedopram", "Oprah", "Umorap", "Siozam", "Tsitalorin" "Cipramil", "Tsitalek" "Tsitalift", "Tsitalon". Tag nrho ntawm cov nyiaj no yuav tsum tau muab tsuas yog ib tug kws kho mob.

Heev ntau cov neeg mob xav nyob rau hauv cov nqe lus nug ntawm yog dab tsi zoo dua: "Citalopram" thiab "Paxil"? Xyuas tshwj xeeb qhia txog hais tias tus thawj yeeb tshuaj yog ntau npaum li cas zoo tshaj lub thib ob. Nws yuav tsum tau muab sau tseg tias cov kev phiv uas tshwm sim tom qab daim ntawv thov ntawm lub "Paxil", muaj ntau pronounced. Yog li ntawd, feem ntau cov kws kho mob pom zoo kom siv nws "Citalopram".

Cev xeeb tub thiab ob lub mis

Hais antidepressant yuav tsum tsis txhob siv rau cov poj niam xeeb tub thiab niam. Kev siv cov tshuaj no nyob rau hauv lub thib peb peb lub hlis tej zaum yuav muaj ib tug tsis zoo feem nyob rau psycho-lub cev txoj kev loj hlob ntawm tus me nyuam. Cov nram qab no ua txhaum cai yog tseem tau: cyanosis, ua pa nyuaj siab, hypoglycemia, ua tsis taus pa, ntuav, convulsions, co, kub tsis khov, nervousness, teeb meem noj, txob taus, nqaij tawg, insomnia, hyperreflexia, qhov quaj, nkees, nkees nkees.

Antidepressant "Citalopram": xyuas

Thaum lub IBS tshuaj no yog tshuaj nrog huab ceev faj. Qhov no yog vim lub fact tias nws lub sij hawm yuav exacerbate nyuaj thiab thiaj li cov neeg mob tus mob.

Yuav ua li cas lawv hais txog rau tam sim no tau txais kev pab txhais tau tias? Muaj ntau cov neeg mob qhia hais txog ib tug muaj kev vam meej kev kho mob tshwm sim "Citalopram" tshuaj. Tom qab pib ntawm txoj kev kho, lawv txoj kev xav hauv lub xeev tau zoo heev sai sai. Txawm li cas los, ib co neeg siv hais tias kho tau lawv tsis tau tos, vim cov tshuaj tau tshwm sim los loj hlob ntawm ib tug xov tooj ntawm cov kev phiv.

Raws li rau cov kws kho mob, lawv kuj sib ceg tias "Citalopram" antidepressant yog ib tug heev npaum thiab zoo txhais tau tias, tiam sis tsuas yog nyob rau hauv tus neeg mob qhov twg nws yog tsis conducive mus rau lub kev loj hlob ntawm sab los. Yog li ntawd, muaj ntau yam cov kws kho mob sim muab cov tshuaj no xwb nyob rau hauv huab mob thiab nyob rau hauv tsawg heev koob tshuaj. Yog hais tias nyob rau hauv thawj lub lim tiam ntawm kev kho mob tsis muaj kev phiv tshuaj tau lawm tias, ces kev kho mob nrog cov tshuaj no ntxiv nrog rau ib co kev nce rau hauv nws cov koob tshuaj (yog tias tsim nyog).