Cov tshuaj 'warfarin. Cov lus qhia rau kev siv

Cov tshuaj "warfarin" cov lus qhia rau kev siv hais txog rau hauv qeb ntawm anticoagulants ntawm indirect kev txiav txim. Cov tshuaj yog tau inhibit qhov kev synthesis ntawm txhaws yam (vitamin K-dependent) raws li protein C thiab S nyob rau hauv lub siab. Pom anticoagulant nyhuv pom nyob rau hauv lub thib peb los yog thib tsib hnub tom qab qhov pib ntawm txoj kev kho thiab tshem tawm tom qab peb mus rau tsib hnub tom qab kawg koob tshuaj. Cov tshuaj no muaj nyob rau cov ntsiav tshuaj daim ntawv.

Nws yog pom zoo thaum noj tshuaj "warfarin" noj cov zaub mov yuav tswj kwv yees li tib yam nqi ntawm vitamin K nyob rau hauv kev noj haus

zaj lus tim khawv

Cov tshuaj no yog qhia rau cov kev tiv thaiv thiab kev kho mob ntawm thrombosis thiab thromboembolism. Los ntawm indications rau tshuaj "warfarin" phau ntawv qhia txog thromboembolism thiab mob venous thrombosis, pulmonary embolism, tsis tshua mob heev ntawm myocardial infarction, postoperative thrombosis. Cov kev npaj yog tshuaj rau kev siv cov thromboembolic tshem tawm los yog phais thrombosis (raws li ib tug ntxiv txhais tau tias) rau atrial fibrillation (hluav taws xob cardioversion), relapsing (rov) cov hlab ntsha thrombosis, embolism nyob rau hauv lub pulmonary leeg. Txhais tau hais tias "warfarin" phau ntawv qhia kom nyob rau hauv vascular cov khoom cuav thiab lub plawv li qub (uas yog tau tso cai nrog lub neej coj kev siv ntawm acetylsalicylic acid). Tsis tas li ntawd, cov tshuaj yog tshuaj rau thrombosis, cerebral, coronary thiab peripheral hlab ntsha, raws li zoo raws li theem nrab kev tiv thaiv ntawm thrombosis los yog embolism thaum lub sij hawm lub blink ntawm ib tug atrial los yog tom qab infarction.

Contraindications mus rau yeeb tshuaj "warfarin" phau ntawv qhia dlhos neeg intolerance, raum los yog hepatic kab mob loj heev, mob ntshav, tawg (hnyav xwm), exacerbation ntawm ulcers nyob rau hauv lub plab los yog duodenum, hemorrhagic diathesis, tsis muaj S thiab C cov nqaijrog, alcoholism, cerebral hemorrhage, raum muaj nuj nqi insufficiency, mob DIC, thrombocytopenia. Taw ib tug yeeb tshuaj thaum lub sij hawm cev xeeb tub.

Feem ntau cov nyom txheej xwm thaum lub sij hawm thawj coj ntawm cov tshuaj "warfarin" yog los ntshav. Nyob rau hauv tsawg zaus, muaj yog necrosis ntawm daim tawv nqaij, muaj lub siab enzymes, raws plab, eczema, plaub hau poob, vasculitis.

ntau npaum

Cov tshuaj no yog qhia rau qhov ncauj thawj coj. Pom zoo ib daim ntawv thov, nyob rau hauv tib lub sij hawm. Cov thawj zaug koob tshuaj - ob thiab ib tug ib nrab mus rau tsib milligrams ib hnub twg.

Tom ntej dosing regimen "warfarin" (INR los yog prothrombin lub sij hawm thaum no yog coj mus rau hauv tus account) yog txiav txim ib lub zuj zus. Nyob rau hauv ob mus rau plaub lub sij hawm los ntawm lub qhov yuav tsum tau muaj zog prothrombin lub sij hawm. Nyob rau hauv rooj plaub no tus INR (thoob ntiaj teb normalized piv) yuav tsum ncav cuag (nyob ntawm seb lub pathology qhov tshwm sim rau los ntshav, thrombosis txaus ntshai) 2.2-4.4.

Rau cov neeg laus cov neeg mob los yog nyob rau hauv ib tug tsis muaj zog txaus mob tshuaj qis koob tshuaj ntawm cov tshuaj "warfarin".

Ua ntej nce lag luam (nyob rau hauv cov ntaub ntawv ntawm predisposition mus rau lub kev loj hlob ntawm thromboembolic teeb meem) txoj kev kho pib ob los yog peb hnub ua ntej cov kev pab.

Nyob rau hauv mob thrombosis kev kho mob yog nqa tawm nyob rau hauv ua ke nrog nrog yeeb tshuaj "heparin" kom txog thaum lub caij thaum cov anticoagulant nyhuv yog tsis qoos manifested (feem ntau yog tsis tau ua ntej lub thib peb thiab thib tsib hnub).

Lub caij ntawm txoj kev kho yog nyob ntawm tus neeg mob tus mob.

Ua ntej qhov pib ntawm kev kho mob yog tsim nyog los mus txiav txim ib tug INR index (nyob rau hauv raws li cov prothrombin lub sij hawm, muab qhov rhiab heev coefficient thromboplastin).

Raws li rau ntau cov neeg mob, cov tshuaj "warfarin" yog tsis tsuas zoo, tab sis kuj yooj yim, vim nws xav tau kev pab yuav tsum tau noj ib zaug xwb ib hnub twg. Nyob rau hauv tas li ntawd, txhais tau tias yog zoo zam lub txim rau, sab los tsis tshua muaj. Txawm li cas los, ua ntej yuav siv cov khoom, koj yuav tsum tham nrog ib tug tshwj xeeb, thiab nyeem cov lus qhia kom zoo zoo.