Kev npaj "Ranitidine": indications rau siv, muaj pes tsawg leeg thiab cov khoom

Cov kab mob ntawm tus mob huam - ib tug heev teeb meem uas muaj feem xyuam rau cov neeg tsis hais hnub nyoog thiab yog txivneej los pojniam. Piv txwv li, gastritis feem ntau thiaj paub hais tias nyob rau hauv cov tub ntxhais hluas thiab tej zaum nyob rau hauv cov me nyuam yaus. Qhov zoo ces, niaj hnub cov tshuaj muaj ntau yam cuab yeej rau cov kev kho mob ntawm inflammatory kev ntawm lub digestive ib ntsuj av. Thiab ib tug ntawm lawv yog cov npaj "Ranitidine". Indications rau siv nyob rau hauv no kev yog heev broad. Yog li ntawd yog dab tsi yog muaj nyob rau hauv nws cov muaj pes tsawg leeg thiab yuav ua li cas zoo xws li ib tug lub cuab tam?

Kev npaj "Ranitidine": Qauv thiab pes tsawg leeg

Lub ntsiab active compound yog ib tug hypochlorite tshuaj ranitidine. Nyob rau hauv nws daim ntawv uas ntuj - ib tug granular dawb hmoov (tej zaum nrog ib tug yellowish tinge) nrog tus yam ntxwv tsis hnov tsw ntawm cov leej faj thiab ntsim saj. Qhov no tshuaj muaj antagonistic zog tiv thaiv histamine H2 receptors.

Cov tshuaj no muaj nyob rau tog twg los nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj los yog nyob rau hauv cov tshuaj rau cov intramuscular los yog tso dej raws leeg thawj coj. Muaj kuj yog li-hu ua "effervescent" ntsiav tshuaj rau npaj ib qho kev aqueous tov.

Ntsiav tshuaj yog cov puag ncig, lis-convex zoo, rau sab saum toj them nrog lub teeb txiv kab ntxwv lub plhaub lawm. Raws li koom haum pab tshuaj yog siv: sodium lauryl sulfate, microcrystalline cellulose, colloidal silicon dioxide, pob kws starch, magnesium stearate, titanium dioxide, hypromellose, polyethylene glycol 6000, ethylcellulose thiab daj zas xim.

Rau hnub tim, pharmacological tuam txhab uas muag muaj cov ntsiav tshuaj, uas muaj xws li 150 mg los sis 300 mg ntawm active tshuaj. Tshuaj daws teeb meem muaj nyob rau hauv lub khob vials nyob rau hauv 2 ml ntim.

Pharmacological "Ranitidine" tshuaj

Raws li twb tau hais, lub ntsiab active khoom sib ua zaub mov ntawm cov tshuaj sim cov H2 histamine retsentory. Qhov no tshuaj ua feem nyob rau hauv kev ua hauj lwm ntawm lub parietal hlwb ntawm lub pais plab mucosa. Nyob rau hauv nws cov cawv xaiv inhibited hydrochloric acid, uas ua rau yus mus rau ib tug txo nyob rau hauv lub ntim tawm txim liab pais plab kua txiv, thiab txo nws acidity. Los ntawm txoj kev, qhov no yog vim li cas cov kev npaj "Ranitidine" kub siab no zoo heev.

Nws yuav tsum tau muab sau tseg tias histamine receptor blockers txo lub concentration ntawm digestive enzymes (pepsin), nyob rau hauv pais plab kua txiv. Inhibition ntawm secretion tsim pom tej yam kev mob rau kev kho ntawm ulcers nyob rau hauv lub mucosa uas lawm accelerates tus zoo txheej txheem.

Tsis tas li ntawd, active tshuaj Cheebtsam muaj feem xyuam rau lub cheeb tsam gastroduodenal, ua cov kev ua ntawm lub zos tiv thaiv mechanisms, ua qhov qee ntawm kev tiv thaiv txheej secretion. Cov tshuaj kuj accelerates lwm.

Nyob rau tib lub sij hawm cov tshuaj tsis muaj ib co txaus ntshai los ntawm lub cev. Nyob rau hauv kev, nws tsis cuam tshuam rau concentration ntawm calcium ions nyob rau hauv cov ntshav, nws tsis disturb tus endocrine system muaj tsis ntxim rau cov txheej txheem ntawm spermatogenesis. Cov kev kawm no tseem pom tias cov tshuaj muaj tsis muaj carcinogenic zoo thiab tsis ua rau change. Nyob rau lwm cov tes, active tshuaj penetrates rau hauv lub placental barrier thiab mus rau hauv niam cov kua mis.

Tom qab tau txais cov tshuaj no yog sai absorbed los ntawm cov phab ntsa hauv lub digestive ib ntsuj av. Nws siab tshaj plaws nyob rau hauv concentration cov ntshav cai tom qab xwb 2-3 teev. Nyob rau hauv feem ntau tus neeg mob, cov nyhuv kav txog 12 teev. Thaum lub sij hawm metabolism cov hloov dua siab tshiab nyob rau hauv lub siab. Kiag tas los ntawm ob lub raum tsis pub dhau hnub tom qab thawj coj.

Kev npaj "Ranitidine": indications rau kev siv

Qhov no tshuaj yog dav siv raws li ib tug antiulcer neeg sawv cev. Txawm li cas los, muaj ntau ntau yam mob nyob rau hauv uas cov kws kho mob muab tshuaj "Ranitidine". Indications rau kev siv muaj xws li:

• mob loj heev kub siab;
• plab thiab me me plob tsis so tswj kab mob;
• hnub no lug siv tshuaj "Ranitidine" gastritis;
• hais rau nws siv no kuj esophagitis, uas yog tshwm sim los ntawm ntuav rau hauv cov hlab pas ntawm pais plab txheem, los yog txuam nrog ua txhaum cai ntawm cov kev ntseeg ntawm mucosal ntaub so ntswg;
• tshuaj pab cov neeg uas muaj dyspepsia nyob rau hauv cov neeg mob, yog hais tias nws yog nrog los ntawm mob heev nyob rau hauv lub epigastric cheeb tsam, ua khub nrog cov pluas noj;
• formulation thov nyob rau hauv cov kev kho mob ntawm tej yam benign qog;
• raws li adjunctive kev kho siv nyob rau hauv aspiration pneumonitis thiab mob caj dab rheumatoid;
• lub cuab tam yog ib feem ntawm txoj kev kho ntawm los ntshav nyob rau hauv lub qaum seem ntawm digestive system;
• raws li ib tug tiv thaiv kev tshuaj rau cov neeg mob uas tau muaj kev phais rau tus mob huam kabmob.

Ib tug muaj tsuas mus nco ntsoov tias mob kab mob - yog tsis tsuas yog cov kab mob uas yuav tsum tau kev kho mob nrog "Ranitidine" tshuaj. Indications rau siv xws li kev tiv thaiv ntawm exacerbations mob gastritis thiab peptic rwj.

Yuav ua li cas noj cov tshuaj?

Ntawm cov hoob kawm, ua ntej yuav siv cov tshuaj no yuav tsum tau nrog ib tug kws kho mob. Tag nrho cov koob tshuaj yog txiav txim ib lub zuj zus, txij li thaum lawv nyob ntawm seb muaj hnub nyoog thiab kev mob ntawm tus neeg mob, daim ntawv ntawm tus kab mob, lub hom phiaj ntawm kev txais tos (kev kho mob los yog kev tiv thaiv):

• Tus neeg laus cov neeg mob qhia tau hais tias tshuaj nrog ib tug koob ntawm cov active tshuaj 150 mg ib hnub ob zaug. Nyob rau hauv tej rooj plaub, cov kws kho mob pom zoo kom noj ob ntsiav tshuaj sai li sai tau ua ntej yuav mus pw.
• Rau kev tiv thaiv los ntshav tus neeg mob yog txhaj intramuscularly (los yog intravenously) ntawm 0.05 - 0.1 g ntawm ua mib ntawm 6-8 teev (cov koob tshuaj tej zaum yuav muab tau ntau zog rau 0.9 g, yog tias tsim nyog).
• Cov me nyuam hluas, yuav siv sij hawm nyob rau hauv 150 mg ib hnub ob zaug.
• Nyob rau hauv cov kev kho mob ntawm cov benign qog pom zoo koob tshuaj yog 150 mg ntawm active ingredient peb zaug ib hnub twg.

Raws li ib tug txoj cai, cov kev kho mob ntev yog nruab nrab ntawm plaub mus rau yim lub lis piam. Thaum nws los txog rau kev tiv thaiv, nws yog pom zoo rau ib co neeg mob uas noj cov tshuaj rau ob peb lub hlis thiab tej zaum ib xyoo, tab sis nyob rau hauv qhov kev kho mob saib xyuas thiab tu ncua endoscopic kev tshawb fawb.

Contraindications rau kev siv ntawm cov tshuaj "Ranitidine"

Zoo li lwm yam kev tshuaj, cov tshuaj no yuav siv tau tsis yog txhua tus neeg mob. Nyob rau hauv kev, nws yog txwv tsis pub muab siv rau cov kev kho mob ntawm cov poj niam thaum lub sij hawm cev xeeb tub thiab lactation, raws li cov active tshuaj tau yooj yim mus rau mus rau hauv cov mis nyuj thiab dhau lub placental barrier. Contraindication yog npau taws me ntsis rau tej feem ntawm cov tshuaj substance. "Ranitidine" yog tsis siv nyob rau hauv cov kev kho mob ntawm cov me nyuam nyob rau hauv 14 lub xyoos.

Ntxiv mus, lub cuab tam siv rau kev ceev faj rau cov kev kho mob ntawm cov neeg mob mob siab los yog raum tsis ua hauj lwm, thiab mob porphyria thiab mob npuas paug.

Yuav ua li cas tshwm sim tsis zoo yuav tshwm sim thaum lub sij hawm kev kho mob?

Tu siab, lub active tshuaj tivthaiv cuam tshuam zoo tag nrho hloov khoom nruab nrog nruab. Yog li ntawd, nyob rau hauv ib co neeg mob cov tshuaj yuav tsum paired nrog ib co kev phiv tshuaj:

• Feem ntau muaj cov mob taub hau, nkees nkees, muaj zog ntxhov siab vim, nkees, kiv taub hau, qhov muag plooj tsis pom kev. Nyob rau hauv loj mob, cov tshuaj yuav ua tau kom tsis meej pem, txoj kev loj hlob ntawm kev nyuaj siab, hallucinations.
• Tau ua txhaum cai ntawm cov hlab plawv system, nyob rau hauv particular, ib tug txo nyob rau hauv cov ntshav siab, aplastic los yog hemolytic anemia, arrhythmia, tachycardia, thrombocytopenia, tsis tshua - hloov hlwb pob txha hypoplasia.
• Cov kev tsis haum yog feem ntau nrog los ntawm cov tsos ntawm daim tawv nqaij sawv pob thiab khaus, kub ib ce, o, erythema. Heev tsis tshua cov tshuaj ua rau anaphylactic poob siab.
• Tej zaum ua rau xeev siab thiab ntuav, mob plab. Heev tsuj tsawg kev kho mob ua rau txoj kev loj hlob ntawm pancreatitis thiab ib co ntaub ntawv ntawm tus kab mob siab.

Thaum tshwm sim ntawm tej kev phiv yuav tsum tsis txhob noj cov tshuaj thiab piav qhia txog cov tsos mob rau kev kho mob sawv.

Cov lus qhia ntxiv txog cov tshuaj

Ua ntej yuav noj cov tshuaj no, raws li ib tug txoj cai, nqa tawm ib txhij txhua kev soj ntsuam, vim nws yog qhov tseem ceeb los xyuas kom meej qhov uas tsis muaj hlav nyob rau hauv lub plab thiab hnyuv. Lub fact tias cov tshuaj yuav los npog lub ntsiab ntawm cov tsos mob cancer.

Long-term kev kho mob ntawm cov neeg mob nrog ib tug tsis muaj zog txaus tiv thaiv kab mob thiab qaug ntawm lub cev yuav ua rau cov kab mob poob siab plab ntaub so ntswg.

Txais tos "Ranitidine" yuav tsum tau nres maj, hnub tom qab hnub, txo cov tshuaj tsawg. Ceev tshem ntawm cov tshuaj yuav ntxias ib tug exacerbation ntawm peptic rwj kab mob.

Raws li siv yeeb tshuaj cov kev sib tshuam "Ranitidine" nrog rau lwm cov tshuaj?

Heev feem ntau txoj kev kho muaj xws li ob qho tib si ntawm kev siv lub medicament thiab npaj, antacids, uas txo acidity nyob rau hauv lub plab. Nyob rau hauv xws li mob, tus so ntawm tau ntawm cov tshuaj no yuav tsum muaj tsawg kawg yog 1-2 xuab moos.

Kev npaj "Ranitidine" impedes haum ketoconazole, thiab kuj cheeb qhov uas cov metabolic dab nyob rau hauv lub siab diazepam, metronidazole, lignocaine thiab ib co lwm yam npaj. Incidentally, haus luam yeeb heev thiaj li cov nyhuv ntawm lub txais tos ntawm lub cuab tam.

Kev npaj "Ranitidine": tus neeg mob xyuas

Xyuas ntawm cov neeg mob uas siv cov tshuaj, feem ntau zoo. Cov neeg nquam paj nquam nruas yeej pom cov nyhuv ntawm no kev kho mob. Kev npaj "Ranitidine" pab tshem tawm kub siab, eliminates lub ntsiab ntawm cov tsos mob gastritis. Cov kev pab cuam ntawm cov tshuaj no yuav tsum tau ntaus nqi, thiab yog ib tug raug tus nqi pheej yig. Phiv tshua yog tsis tshua muaj heev.