Ntsiav tshuaj "Zilt": cov lus qhia rau kev siv

Kab mob (CVD) yog ib lub txim ntawm neeg ua cuam tshuam nyob rau hauv mob kev ua si thiab cov hlab ntsha. Rau cov kab mob plawv xws li coronary mob plawv (lub plawv sib cem), ntshav siab (tawg), cerebrovascular kab mob (stroke), rheumatic kab mob plawv, peripheral arterial kab mob, lub plawv tsis ua hauj lwm, thiab kab mob plawv (congenital). CVD yog tsim raws li ib tug tshwm sim ntawm kev haus luam yeeb, lub cev inactivity, tsis zoo noj zaub mov zoo.

CVD yog kho nyob rau hauv ntau txoj kev. Piv txwv li, mob hauv lub plawv tsis ua hauj lwm ntse kho los ntawm cov tshuaj. Lub ntsiab lub hom phiaj ntawm qhov kev kho no yog los txo cov load rau hauv lub plawv thiab kom nws siv muaj nuj nqi. Cov kab mob xws li ischemic stroke thiab heart attack myocardial infarction kuj yog tau los kho npaj. Tshuaj "Zilt" tau raug tsim rau lub hom phiaj no.

"Zilt": cov lus qhia rau kev siv

"Zilt" yog muaj raws li zaj duab xis-coated ntsiav tshuaj, lub ntim yuav tsum distinguished los ntawm tus xov tooj ntawm cov ntsiav tshuaj - ib tug tsawg kawg nkaus ntawm 14, tshaj plaws ntawm 90. Txhua ntsiav tshuaj muaj 75 grams ntawm clopidogrel.

Los ntawm kev txheeb xyuas, "Zilt" ntsiav tshuaj nyiam lub restoration ntawm platelet muaj nuj nqi tom qab ib tug ob peb hnub (7 mus rau 10) tom qab tus neeg mob nres siv cov tshuaj. Cov tshuaj siv los kho tus kab mob plawv, muaj antiagregatsionnym physiological nyhuv. Lub ntsiab active ingredient ntawm cov kev npaj "Zilt" neeg siv daim ntawv thov hu clopidogrel pub losis tswvyim dabtsi ntawm ADP rau platelet receptors, uas tau nyob rau hauv inhibition ntawm ADP-dependent platelet aggregation.

Cov tshuaj rau cov neeg laus - ib ntsiav tshuaj (75 mg) rau ib hnub, noj mov tsis yog nyob. Duration ntawm kev kho mob feem ntau yog kav 12 lub hlis tab sis tej zaum yuav tau tom raws li nyob rau hauv lub hom ntawm tus kab mob thiab nws heev. Qhov siab tshaj plaws cov nyhuv yuav tsum tom qab 3 lub hlis.

Noj zilt cov lus qhia rau kev siv pom zoo rau cov kev tiv thaiv ntawm tus kab mob plawv: ischemic stroke, plawv tuag nyob rau hauv cov neeg mob uas mob loj heev ces atherosclerosis, heart attack myocardial infarction. Tsis tas li ntawd, "Zilt" yog qhia nyob rau hauv cov neeg mob uas peripheral arterial kab mob.

Qhov no tshuaj yog ua rau lub xub ntiag ntawm npau taws me ntsis rau clopidogrel los yog lwm yam ntawm cov kev npaj. Tsis tas li ntawd, yog vim li cas rau contra yuav ua tau pathological los ntshav, siab kawg (hnyav), cev xeeb tub thiab lactation, raws li zoo raws li lub hnub nyoog ntawm 18 xyoo.

Ceev faj yuav tsum raug siv zilt nrog npaj muaj warfarin, heparin los yog lwm yam thrombolytic agents, txwv tsis pub qhov uas yuav los ntshav. Tsis clinically tseem ceeb los nyob rau hauv cov ntaub ntawv ntawm cov tshuaj nrog nifedipine, atenolol, digoxin, cimetidine, phenobarbital, theophylline los yog estrogens. Kev nyab xeeb siv nrog tolbutamidom thiab fenotionom. Nyob rau hauv tas li ntawd, cov pa haum ntawm clopidogrel cuam tshuam antacids.

Qhia tsuas cov ntaub ntawv ntawm overdose "Zilt" npaj: twb npaum li cas 14 ntsiav tshuaj (1050 mg ntawm clopidogrel). Mob thiab cov tsos mob ntawm intoxication nyob rau hauv cov ntaub ntawv no tsis yog cai, thiab muaj tsis muaj kev xav tau tshwj xeeb kev kho mob. Rau cov tshuaj yog tsis muaj ib yam tshuaj. Yog hais tias tsim nyog los tshem tawm cov nyhuv ntawm clopidogrel, platelet transfusion loj ua.

Zilt phau ntawv qhia kom mus cia nyob rau hauv ib tug txias, qhuav qhov chaw, kev tiv thaiv los ntawm tshav ntuj. Cov nyiaj pub cia kub yog 25 ° C. Cov kev npaj no yog tsim rau peb lub xyoos. Tau zilt cov lus qhia rau kev siv pom zoo xwb nyob rau cov lus tim khawv ntawm tus kws kho mob - yuav tsum tsis txhob self-medicate.