Nce prolactin: ua, cov tsos mob, kev kho mob, txim

Yog hais tias tsa lawm prolactin, lub ntxhov cev ntas thiab hormonal tshuav nyiaj li cas, thiab muaj yog ntxiv lawm tshob los yog teeb meem nqa ib tug me nyuam. Yog li ntawd, cov poj niam xav tau los mus txiav txim nyob rau hauv nws qib nyob rau hauv cov ntshav thaum lub sij hawm cev xeeb tub npaj.

Prolactin yog ua los ntawm cov pituitary caj pas - endocrine caj pas nyob rau hauv lub hlwb. Hypothalamus ntawm lwm yam uas tus txheej txheem no. Lawm ntau ntau rhiab heev rau lwm yam. Yog li ntawd, siab prolactin tej zaum yuav rau cov nram qab yog vim li cas:

• tshuaj;

• raum tsis ua hauj lwm;

• kev nyuaj siab;

• mob npuas paug;

• pw tsaug zog;

• Cushing tus syndrome;

• Addison tus kab mob ;

• acromegaly;

• sarcoidosis;

• neyrotuberkulez;

• o;

• lub postpartum lub sij hawm;

• cev xeeb tub;

• txiv mis stimulation;

• kev pub niam mis;

• kev sib deev com;

• tshuaj loog;

• kev raug mob thiab kev phais rau lub hauv siab.

Thaum sib txawv lub sij hawm ntawm lub voj voog ntawm cov hormone theem nyob rau hauv cov ntshav mas nws txawv ntawm 6 mus rau 28 ng / ml. Yog xav tau kev txhim khu kev qha tau yuav tsis tau tom qab tsom xam cov pw tsaug zog los yog cov txheej txheem. Lub secretion ntawm prolactin tshwm sim pulsed, lub zaus nyob theem ntawm lub voj voog. Tseem muaj hnub hloov mus hloov los ntawm cov theem, piv txwv li, tom qab waking lawm concentration tsawg tshaj plaws. Tom qab ntog pw tsaug zog nws secretion qab thiab loj hlob nyob rau hauv ib tug npau suav.

Ib feem peb ntawm cov neeg mob uas tau tsa prolactin, pom pituitary adenoma. Yog hais tias nws loj loj, cov hormone theem yog ntau tshaj li 100 ng / mL. Lower cov nqi yuav ua tau microadenomas ntawm me me ntau thiab tsawg pab, tsis kuaj los ntawm X-ray.

Qhov tseem tuav txoj kev rau mob ntawm pituitary hlav - ib tug MRI. Nws yog tsim nyog los kis tau rau hauv qhov kev npaj ntawm tus me nyuam, yog hais tias muaj yog lub sijhawm twg los ntawm ib tug adenoma, raws li loj mob tej zaum yuav ua rau kom mob.

Qhov ntev pituitary microadenomas tsis pub tshaj 1 cm. Lawv loj hlob heev maj mam thiab yog feem ntau benign. Macroadenomas txoj kab uas hla ntau dua tshaj 1 cm. Lawv nrog mob taub hau, hloov nyob rau hauv nrig txog kev pom teb thiab tej zaum kuj ua kom tiav tsis ntawm nws. Thaum nrhiav kom tau macroadenoma yog tsim nyog sib tham ntawm ib tug neurosurgeon. Nws ua rau ib tug txiav txim txog kev phais. Thaum lub sij hawm uas cev xeeb tub microadenomas feem ntau tsis hloov, tiam sis hlav ntawm loj loj nyob rau hauv 20% ntawm cov neeg loj hlob.

Prolactin yog tseem nquag tsa nyob rau hauv lub raum tsis ua hauj lwm (mob). Thaum raum hloov ib tug normalization ntawm nws cov pa.

Yog hais tias prolactin yog tsa, rau lub hom phiaj nyob rau hauv cov kev kho mob ntawm cov nram qab no:

• txo cov theem;

• restore voj voog;

• txo lub qog loj, yog tias tam sim no.

Ib tug ntawm cov tshuaj siv kom txo tau cov tshuaj - yog Parlodel, uas yog ib tug dopamine agonist. Nws cheeb qhov uas cov pa ntawm prolactin los ntawm stimulating receptors nyob rau hauv lub hlwb. Koob nyob rau hauv lub heev thiab qhov xwm ntawm tus kab mob no. Tom qab cov kev taw qhia ntawm bromocriptine voj voog yog rov qab los tom qab ib tug nruab nrab ntawm 7 lub lis piam. Txawm tias ib co neeg mob nws tshwm sim nyob rau hauv ob peb hnub.

Bromocriptine feem ntau siv li ob peb zaug ib hnub twg. cov tshuaj yuav tau nce yog tias tsim nyog. Kev kho mob yuav tsum ntev li ob peb mus tom qab lub restoration ntawm poj niam los mus tiv thaiv tsis tshua mob heev. Tshwm sim los ntawm bromocriptine:

• qaug zog;

• kiv taub hau;

• mob taub hau;

• ntuav;

• qhov ncauj qhuav;

• xeev siab.

Yuav kom nce prolactin yuav ua rau hypothyroidism. Tau txais Gomonov nyob rau hauv cov ntaub ntawv no ua rau yus lub normalization ntawm cov theem.

Indications rau prolactin rau kev tsom xam cov nram qab no:

• txha;

• gynecomastia;

• qis potency thiab libido;

• hirsutism;

• rog;

• Hnyav kawg nkaus;

• lactation mob;

• ntxiv lawm tshob;

• anovulation;

• mis;

• xaiv ntawm lub txiv mis;

• amenorrhea, oligomenorrhea;

• cyclic mis mob.

Yog li, prolactin ntau zog, nyob rau hauv feem ntau tus neeg mob vim pituitary adenomas. Nyob rau hauv tas li ntawd, ib qho ua kom muaj nws cov high concentration yog hypothyroidism. Tus muaj zog concentration ntawm prolactin ua rau muaj kev cuam tshuam ntawm lub cev muaj nuj nqi thiab lub tsis tuaj kawm ntawv ntawm ovulation, li ntawd, lub conception thiab nyuam yuav xyaum tsis yooj yim sua. Kev kho mob muaj kev txo cov theem, tshem tawm ntawm tus kab mob no ua rau thiab rov qab voj voog.