Tshuaj rau migraine - triptans. Dosing thiab nta ntawm kev txiav txim

Migraine - qhov no yog ib qho ntawm feem ntau cov kab mob, uas muaj peev xwm txo tau cov efficiency ntawm ntau cov neeg mob. Tus kab mob no muaj feem xyuam rau txog li 6% ntawm cov txiv neej thiab 18% cov poj niam. Cov nuj nqis yog heev. Txawm li cas los, 60% ntawm cov neeg uas raug kev txom nyem los ntawm tus kab mob no, nws tus kheej tau ntau yam analgesics rau mob. Raws li ib tug txoj cai, tej yam ua tau tsuas yog thab cov chav kawm ntawm tus kab mob no.

Hais tsis muaj analgesics

Muaj coob tus neeg uas raug kev txom nyem los ntawm yastes yastaw, tsis paub yuav ua li cas kom tsis txhob tawm tsam, thiab lig dhau lawm mus coj painkillers. Los ntawm no kev kho mob nyhuv yog heev me me. Los yog nws tsis mus kawm. Qhov no ua rau kom tus neeg mob pib maj mam nce ntau npaum cov tshuaj. Raws li ib tug tshwm sim ntawm tej yam ua tau tsuas yog ua rau kom txoj kev pheej hmoo ntawm kev puas tsuaj rau lub raum, lub loj hlob ntawm gastritis. Nyob rau hauv tej rooj plaub, analgesics kom tsawg yuav ua tau kom loj teeb meem - lub rov tshwm sim ntawm cov tshuaj hob mob taub hau.

Uas yog vim li cas yog tias koj muaj tej yam ntawm migraine yuav tsum xa mus rau cov kws tshwj xeeb. Self-tshuaj nyob rau hauv cov ntaub ntawv no, muaj peev xwm tsuas thab tus neeg mob tus mob. Nyob rau hauv lub lig puv 19 xyoo pua cov neeg tshiab yog tsim antimigraine tshuaj - xim agonists ntawm 5 NT 18 / D-receptors. Tej yam yog derivatives ntawm 5-gidroksitritamina. Abbreviated lawv lub npe - triptanity. Tshuaj rau migraine no tiam yog ntau npaum li cas npaum li pa analgesics. Nyob rau hauv tas li ntawd, cov cuab yeej ua ntau mus siv cuag mus rau tag nrho pawg ntawm cov neeg mob.

Yuav ua li cas ua cov tshuaj

Triptans - lub feem ntau tshaj kev kho mob rau qhov no tsis kaj siab tus kab mob, migraine. Nws yog ntseeg hais tias tag nrho cov tshuaj ua hauj lwm tib txoj kev. Txawm li cas los, ib tug neeg mob yuav pab xwb ib ob peb ntawm ib tug loj tus naj npawb ntawm triptans. Yog li ntawd, qhov kawg xaiv ntawm cov khoom no tseem thiaj tau tuaj nrog tus neeg mob. Yuav kom txiav txim seb qhov hauj lwm zoo ntawm ib tug triptane, tsim nyog mus kuaj cov tshuaj thaum lub sij hawm migraine tawm tsam. Thaum kawg peb ntawm lawv yuav tsum mus. Yog hais tias cov tshuaj tau pab, nws yuav siv tau nyob rau hauv lub neej yav tom ntej. Ntawm cov hoob kawm, cov kev xaiv yuav zoo heev cuam tshuam qhov nqi ntawm ib tug triptan. Tom qab tag nrho, cov tshuaj tsis yog pheej yig. Nyob rau hauv tas li ntawd, txhua formulation muaj ib tug tej yam analgesic nyhuv. Nyob rau hauv tas li ntawd, nws yog tsim nyog los paub tias dab tsi yog cov triptans rau migraine, feature txiav txim, txoj kev txais tos thiab contraindications.

Ua ntej ntawm tag nrho cov, xws tshuaj muaj ib tug cawv rau receptors txog ntsha phab ntsa. raws li ib tug tshwm sim nws ua narrowing dilated cerebral cov hlab ntsha, raws li zoo raws li yuav pab tau kom tsis txhob mob taub hau.

Tej npaj muaj ib tug txaus siab selectivity. Uas yog vim li cas triptans muaj ib cov nyhuv rau cov hlab ntsha Dura. Qhov no yog ib tug ntawm lawv specialties. Txawm li cas los, lawv muaj tsis ntxim rau cov peripheral thiab coronary hlab ntsha. Nws yuav tsum tau muab sau tseg hais tias triptans - migraine tshuaj uas thaiv qhov tshwm sim ntawm qhov mob nyob rau receptor theem, muaj nyob rau hauv cov leeg nrob nucleus ntawm lub trigeminal paj. Qhov no zoo heev thiaj li rhiab heev rau mob.

Nyob rau hauv tas li ntawd, cov tshuaj yuav txo tau lub zaus ntawm rov, raws li zoo raws li ntau zoo tshem tawm kab mob, xws li suab thiab photophobia, ntuav thiab xeev siab.

Liaj teb ntawm kev txiav txim ntawm triptans

Yuav kom to taub li cas cov tshuaj ua, yog muab cov kev qhia tswj:

1. Vasoconstriction, nyob rau hauv lub hlwb.
2. Anti-inflammatory kev txiav txim: yuav txo tau ntawm o, uas txo nws hwj siab rau lub paj txoj.
3. Kev tsim txom siab trigeminal paj thiab txo nws rhiab heev rau mob.

Raws li koj tau pom, triptans rau migraine - qhov zoo tshaj cov tshuaj uas yuav tsis txhob tawm tsam ntawm tus kab mob. Qhov loj tshaj plaws yog xaiv qhov yog tshuaj

Zoo thiab tsis zoo ntawm cov triptans

Cov qhov zoo ntawm cov khoom xws li yog muab zoo tswj ntawm kev mob thiab mob cov tsos mob, ceev kev txiav txim. Nyob rau hauv tas li ntawd, lub triptans yuav siv tau rau cov kev kho mob ntawm tus kab mob nyob rau hauv hnub nyoog sib txawv pawg.

Ntawm cov hoob kawm, tej tshuaj muaj disadvantages. Zoo kawg nkaus pab triptans rau migraine thiab mob taub hau. Txawm li cas los, lub spectrum ntawm kev txiav txim ntawm cov tshuaj yog tseem tsis to taub. Nyob rau hauv tas li ntawd, tsis yog txhua tus muaj peev xwm mus coj triptans raws li lawv noj qab haus huv. Nws yog txwv tsis pub siv cov tshuaj rau cov neeg kev txom nyem los ntawm coronary mob plawv. Nyob rau hauv pawg yog cov neeg uas muaj cov ntshav txhaws thiab phem tawg yog tam sim no.

Tus thawj tiam

Migraine npaj - triptans - conditionally faib ua ob peb pab pawg. Qhov no yog tus thawj thiab tus thib ob tiam. Txhua cov tshuaj nws muaj nws tus kheej zoo thiab disadvantages. Yog li ntawd, cov thawj tiam ntawm yeej muaj tseeb "Sumatriptan". Qhov no yog thawj yeeb tshuaj. Nws yuav luag tag to taub thiab yog ib yam ntawm cov txheej txheem nyob rau hauv cov kev kho mob ntawm migraine. Nyob rau hauv soj ntsuam nws coj 60 txhiab tus neeg tau koom tes. Rau cov thawj lub sij hawm cov tshuaj twb nrhiav tau los ntawm GlaxoSmithKline nyob rau hauv 1989.

Yeej "sumatriptan" yog pom tau hais nyob rau hauv daim ntawv ntawm cov pa ntsiav tshuaj, coated ntsiav tshuaj, thiab tshuaj tsuag. Txhua yam ntawm lawv ua hauj lwm identically. Qhov siab tshaj plaws cov nyhuv tom qab noj cov tshuaj no tshwm sim tom qab ob thiab ib nrab sij hawm, thiab tshuaj tsuag - 90 feeb.

ob tiam

Triptans - tshuaj rau migraine, teej tug mus rau qhov no pab pawg neeg - yog heev heev. Nyob rau hauv tas li ntawd, lawv tsis txaus kawm. Tsim lawv nyob rau hauv daim ntawv ntawm cov ntsiav tshuaj. Cov qhov zoo tshaj yog:

1. "Natriptan" - cov nyhuv tau tau cai rau txog ib teev tom qab haus. Mob yog txo. Maximum nyhuv tshwm sim nyob rau hauv ib ob peb teev.
2. "Frovatripan" - qhov no tshuaj yog dog dig weaker, tab sis nws tau txais tsawg manifest phiv tsis kaj siab.
3. "Zolmitriptan" - ua hauj lwm tom qab 15 feeb tom qab thawj coj. Qhov siab tshaj plaws cov nyhuv yog tiav tom qab txog ib teev. Qhov no tshuaj yog heev zoo mus tua lub ncov.
4. "Rizatriptan" - uas zoo sib xws rau qhov kev npaj ntawm thawj tiam, tab sis muaj ib tug ntau pronounced nyhuv.
5. "Almotriptan" - qhov no tshuaj yog superior rau "Sumatriptan" ob peb lub sij hawm nyob rau hauv efficiency. Qhov siab tshaj plaws cov nyhuv yog tiav tom qab 1.5 teev.
6. "Relpaks" - qhov no tshuaj yog ntau inventive nyob rau hauv cov nqe lus ntawm tej yam rau lub paj hlwb cov ntshav hlab ntsha. Txawm hais tias kev kawm yog heev uas zoo sib xws rau "sumatriptan".

Tshuaj rau migraine (triptans): nqi thiab cov tswv yim rau kev txais tos

Yuav kom ua rau nws ntshiab uas tshuaj muaj nyob, peb muaj ib lub rooj:

nta txais tos

Yog li ntawd, yuav ua li cas zoo tshaj plaws los coj triptans rau migraine thiab mob taub hau? Cov lus qhia nyob rau hauv cov ntaub ntawv no yuav pab tau los mus txiav txim ntau npaum thiab lub sij hawm ntawm kev txais neeg kawm. Qhov loj tshaj plaws - nco ntsoov tias nyob rau hauv cov ntaub ntawv ntawm kev mob uas tsub kom maj mam thiab tsis muaj qhov xwm ntawm migraine, noj cov tshuaj xws li ib tug lub tswv yim ua rau tsis muaj kev txiav txim zoo. Nyob rau hauv cov ntaub ntawv no, koj yuav tsum siv sij hawm ib tug uas tsis yog-kev analgesic. Qhov no yog qho tseem ceeb heev. Feem ntau, triptans yuav tsum tau coj tom qab qhov kawg ntawm lub aura, los yog tsis pub dhau ob xuab moos tom qab qhov pib ntawm tsis xis nyob. Nyob rau hauv tas li ntawd, thaum ib tug triptan migraine thiab yuav siv tau nrog rau lwm cov tshuaj, xws li metoclopramide los yog domperidone.

Raws li rau cov tshuaj tsuag, lawv yuav tsum siv tau rau ib tug txaus cov lus hais xeev siab thiab, ntawm chav kawm, ntuav. "Imigran" yuav raug coj mus rau tshem tawm raws li txoj cai migraine. Triptanity yuav muab tsis tau tsuas yog rau txoj kev loj hlob ntawm tus kab mob, tab sis kuj nyob rau hauv lub sij hawm ntawm tawm tsam nyob rau hauv thiaj li yuav tiv thaiv. Qhov no yog tso cai nyob rau hauv tus neeg mob thaum:

1. Tus neeg mob lub neej zoo tau deteriorated.
2. Narcotics yuav muab yog heev yooj yim mus kho.
3. Migraine tawm tsam tshwm sim ntau tshaj ob zaug nyob rau hauv 30 hnub.

Yuav ua li cas mus nrog ib tug mob taub hau

Yuav kom tshem tawm ib tug migraine nres, nws yog tsim nyog los ua ntej sim muab 1,000 milligrams acetylsalicylic acid, lub qab zib haus uas muaj caffeine, los yog 10 milligrams ntawm cov tshuaj "Motilium". Yog hais tias tom qab 45 feeb tus mob taub hau tsawv, nws yog tej zaum yuav siv ib tug triptan.

Nws yuav tsum tau muab sau tseg tias nyob rau hauv tej qhov chaw rau peb tawm tsam nonspecific analgesic tsis tau muab cov kev kawm, koj yuav tam sim ntawd muab lub tshuaj rau migraine. Yog hais tias muaj yog ib tug aura, siv cov tshuaj aspirin nqi tsuas yog tom qab nws tau pib, thiab tom qab qhov tshwm sim ntawm ib tug mob - tshuaj rau migraine (triptans).

Yuav ua li cas yog hais tias tus mob xa rov qab?

Kwv yees li 50% ntawm cov neeg mob muaj yog ib tug rov qab los ntawm mob taub hau nyob rau hauv ib ob peb hnub. Kws txawj pom zoo kom hais tias nyob rau hauv xws li ib tug teeb meem no dua noj cov tshuaj rau migraine - triptans. Nws yuav tsum tau nco ntsoov hais tias hais txog lub siab tshaj plaws txhua txhua hnub koob tshuaj ntawm cov tshuaj. Noj cov tshuaj yog tsis muaj ntxov tshaj li ob xuab moos tom qab thawj zaug ntsiav tshuaj. Yog hais tias tus mob taub hau yuav zam lub txim rau, tus neeg mob tej zaum yuav hloov triptans nonspecific analgesic.

Nws yog ib nqi sau cia hais tias lub tsis xis nyob rov qab yog feem ntau pom nyob rau hauv cov neeg mob uas ib tug txaus ntev bouts uas yuav kav tsis tau noj mob tshuaj rau ntau tshaj 24 teev. Txawm thaum noj tej yam triptan zaus ntawm tej txheej xwm tseem muaj nyob zoo unchanged. Txawm li cas los, cov kws txawj ntseeg tau hais tias kev siv ntawm "Eletriptan" thiab "naratriptan" yuav pab txo tau cov naj npawb ntawm tshiab tawm tsam.

Yog hais tias muaj yog tsis muaj tshwm sim

Muaj tej lub sij hawm thaum cov tshuaj rau migraine (triptans) thiab uas tsis yog-kev tshuaj tsis muab cov kev kawm tshwm sim thiab tsis tshem tawm qhov mob. Nyob rau hauv cov ntaub ntawv no, ib tug kws kho mob yuav muab tshuaj rau ib tug complex txoj kev kho, uas muaj txoj kev saib xyuas anticonvulsant tshuaj, raws li zoo raws li B-blockers. Cov tshuaj xws li "nadolol," "acebutolol", "penbutolol", "Labetanol", "Betaxolol" thiab lwm tus neeg.

Tshwm sim los ntawm triptans

Cov tshuaj yuav tsum tau noj xwb 10 hnub hauv ib lub hlis. Txwv tsis pub, tej zaum koj yuav muaj kev ib co teeb meem. Ntau heev siv cov triptans yuav ua tau kom mob taub hau, uas tshwm sim nyob rau hauv cov neeg mob uas tau txais cov tshuaj no. Nyob rau hauv tas li ntawd, xws nkaus tshuaj muaj kev phiv, xws li:

1. Ib tug kev xav ntawm warmth thiab mob heev nyob rau hauv lub nqua, nkees nkees, qaug zog, kiv taub hau, rhiab heev.
2. Myocardial plab los yog tus po, ischemic mob plab, raws plab hemorrhagic, qhov ncauj qhuav, mob plab thiab xeev siab.
3. Myalgia thiab nqaij tsis muaj zog.
4. Coronary vasospasm, heart attack myocardial infarction, angina pectoris, tachycardia, palpitations.
5. Polyuria, thiab nquag tso zis.
6. Anaphylaxis, angioedema, urticaria.

Txawm tias tag nrho cov no, triptans rau migraine - ib tug ceev ceev-kuj noj tshuaj. Yog hais tias koj noj cov tshuaj nruj me ntsis raws li cov lus qhia, ces tsis muaj teeb meem. Lub tsuas tseem ceeb disadvantage ntawm xws tshuaj - nqi. Tsis yog txhua tus yuav them taus los yuav xws li ib tug yeeb tshuaj.