"Vilprafen 1000": phau ntawv, analogues, xyuas

Yuav ua li cas yog cov tshuaj "Vilprafen 1000"? Cov lus teb rau qhov no nyuab kho mob qhov teeb meem koj yuav nrhiav tau nyob rau hauv cov ntaub ntawv yog muab los ntawm tsab xov xwm. Tsis tas li ntawd tawm ntawm nws, koj yuav kawm txog yuav ua li cas coj cov tshuaj, yog dab tsi nws meant, seb tus mob tshwm sim thiab contraindications yog tshaj nws yuav tsum tau hloov, thiab hais txog.

Muaj pes tsawg leeg thiab rau hauv daim ntawv ntawm ntim ib tug kho mob ntaus ntawv

Kev npaj "Vilprafen 1000" yuav yuav nyob rau hauv ib tug muag tshuaj nyob rau hauv daim ntawv ntawm cov dawb dispersible ntsiav tshuaj (tej zaum yuav muaj ib tug yellowish tinge). Lawv muaj ib elongated lub cev nrog lub cim thiab lo lus "lub IOSA" rau ntawm ib sab, nrog "1000" xov tooj nyob rau lwm yam. Nws yuav tsum raug sau tseg hais tias qhov no lub cuab tam muaj ib tug Sweet saj thiab aroma ntawm txiv pos nphuab.

"Vilprafen 1000" active tshuaj yam khoom uas yog josamycin. Raws li rau lub koom haum pab Cheebtsam, ces lawv muaj xws li aspartame, giproloza, colloidal silicon dioxide, microcrystalline cellulose, sodium docusate, pos nphuab tsw, thiab magnesium stearate.

Nyob rau hauv lub qhov muag ntawm cov tshuaj nkag mus rau hauv sawv hlwv 5 ntsiav tshuaj muab tso nyob rau hauv ib tug cardboard lub thawv.

Lub pharmacological kev txiav txim ntawm cov tshuaj

Yuav ua li cas yog cov tshuaj "Vilprafen 1000"? Cov lus qhia rau kev siv ntawm cov tshuaj no muaj cov lus qhia hais txog dab tsi lub cuab tam yog ib tug tshuaj tua kab mob teej tug mus rau lub macrolide pab pawg neeg.

Lub mechanism ntawm qhov kev txiav txim ntawm cov tshuaj nyob rau hauv saib xyuas yog kev cob cog rua nrog lub txhaum ntawm cov protein synthesis nyob rau hauv lub hlwb ntawm microbes. Qhov no tej yam yog vim lub reversible losis tswvyim dabtsi ntawm lub active tshuaj los ntawm lub 50s-ribosomal subunit.

Nyob rau hauv kho nqi ntawm cov cuab tam yog muaj peev xwm sawv ntawm exerting ib bacteriostatic nyhuv los ntawm npleem lub tu tub tu kiv thiab kev loj hlob ntawm cov kab mob. Yog hais tias koj tsim nyob rau hauv nruab nrab ntawm o siab ntau, nws yog tau bactericidal nyhuv.

Lub medicament "Vilprafen 1000" yog tshwj xeeb yog active tiv thaiv kab-zoo thiab gram-tsis zoo microorganisms. Yog li ntawd nws tsis cuam tshuam rau enterobacteria. Nyob rau hauv no hais txog, cov kev npaj tej zaum yuav tsis adversely cuam tshuam rau kev mob ntawm lub digestive ib ntsuj av tau microflora.

Nyob rau hauv tej rooj plaub, cov tshuaj tseem active nrog tsis kam mus erythromycin thiab lwm yam macrolides.

Tshuaj ntawm cov tshuaj

tshuaj "Vilprafen 1000" Yuav ua li cas ntev yog absorbed? Coj lub cuab tam hais tias tom qab qhov ncauj thawj coj ntawm lub active keeb ntawm cov tshuaj heev sai absorbed ntawm lub digestive ib ntsuj av. Nyob rau hauv no noj mov tsis muaj feem xyuam rau lub bioavailability.

Qhov siab tshaj plaws concentration ntawm ib tug medicament tiav tom qab txog ib teev tom qab haus. Thaum ib tug ntau npaum ntawm 1 g ntawm lub siab tshaj plaws concentration yog hais txog 2-3 mg / ml.

Lub active tshuaj yog ib tug medicament haum zoo faib nyob rau hauv cov ntaub so ntswg thiab hauv nruab nrog cev (tshwj tsis yog nyob rau hauv lub hlwb). Nyob rau hauv cov ntaub ntawv no, cov tshuaj ua ntau tshaj ntshav thiab khaws cia nyob ib tug kho theem rau ib ntev lub sij hawm.

Josamycin END cai nyob rau hauv lub tonsils, lub ntsws, cov qaub ncaug, tsim kua muag dej thiab tawm hws. Cov tshuaj nkag kis los ntawm tus placental barrier thiab yog secreted nyob rau hauv niam cov kua mis.

Josamycin (active tshuaj tshuaj) yog metabolized nyob rau hauv lub siab. Qhov no ua active metabolites.

Kev npaj muab feem ntau nyob rau hauv lub bile. Tab sis cov tshem tawm ntawm cov zis tsis pub tshaj 10%.

Indications rau kev siv ntawm ib tug kws kho ntaus ntawv

Thaum twg kuv siv cov tshuaj "Vilprafen 1000"? Xyuas txog qhov no medicament peb yuav xav txog rau yav tom ntej. Tam sim no kuv xav qhia rau koj tias cov tshuaj yog tsa xwb nyob rau hauv kab thiab inflammatory kab mob, uas yog tshwm sim los ntawm kab mob rhiab rau qhov chaw:

• diphtheria (raws li ib tug adjunct mus rau kev kho nrog diphtheria antitoxin);
• kab mob ntawm Upper pa ib ntsuj av tau thiab Upper pa ib ntsuj av tau (laryngitis, pharyngitis, otitis media, tonsillitis, sinusitis thiab paratonzillite);
• sab pa ib ntsuj av tau kab mob (exacerbation ntawm tus kab mob bronchitis, mob ntsws, mob ntsws);
• hnoos;
• kub taub hau (thaum muaj npau taws me ntsis rau penicillin);
• kab mob ntawm lub qhov ncauj kab noj hniav (pericoronitis, gingivitis, alveolitis, periodontitis, alveolar rwj);
• psittacosis;
• nqaij mos thiab tawv nqaij (furuncles, folliculitis, pob txuv, abrasions, lymphangitis, rwj, phlegmon, lymphadenitis, txhaum cai loj, mob, hlawv, thiab post-phais kab mob);
• qhov muag mob (dacryocystitis thiab blepharitis);
• erysipelas (thaum muaj npau taws me ntsis rau penicillin);
• anthrax;
• qhov chaw mos mob, thiab mob txeeb zig (cervicitis, urethritis, prostatitis, epididymitis);
• lymphogranuloma venereum ;
• cov kab mob ntawm lub digestive system uas yog txuam nrog rau Helicobacter pylori;
• syphilis thiab gonorrhea (yog hais tias muaj yog ib tug npau taws me ntsis rau penicillin).

Contraindications rau kev siv ntawm cov tshuaj

Nyob rau hauv tej rooj plaub, koj muaj peev xwm siv tsis tau cov tshuaj "Vilprafen Soljutab 1000"? Guest kws txawj hais tias nyob rau hauv cov tshuaj no muaj cov nram qab contraindications:

• cov me nyuam nrog me me yug qhov ceeb thawj (tsawg tshaj li 10 kg);
• mob loj heev mob ntawm lub siab;
• Npau taws me ntsis rau lub active tshuaj;
• Npau taws me ntsis rau cov tshuaj tua kab mob tshuaj teej tug mus rau lub macrolide pab pawg neeg.

Tshuaj "Vilprafen 1000": cov lus qhia rau kev siv ntawm cov tshuaj

Cov tshuaj ntawm cov tshuaj yuav tsum tau txiav txim los ntawm lub mus kawm tus kws kho mob, thiab tsuas yog nyob rau ib tug neeg zus.

Rau cov neeg laus thiab cov me nyuam hluas tshaj 14 xyoo, lub cev ntim ntawm cov nyiaj yog 1-2, nws coj nws tus pom zoo 2-3 teev. Yog hais tias tsim nyog, lub koob tshuaj tej zaum yuav muab tau ntau zog (e.g., mus txog 3 g ib hnub twg).

Lub hnub koob tshuaj rau cov me nyuam, uas nws lub cev hnyav yog 10 kg, yog muab raws li nyob rau hauv lub xam ntawm 40-50 mg ib kg lub cev hnyav. Txais ntawm cov tshuaj tsim nyog los nqa tawm 2-3 lub sij hawm ib hnub twg.

Raws li cov foregoing, nws yog ib qho yooj yim los mus laij hais tias ib tug me nyuam uas 10-20 kg yuav tsum tau muab 250-500 mg tshuaj ib hnub ob zaug (ib tug peb lub hlis twg los yog ib nrab ib tug ntsiav tshuaj, pre-yaj nyob rau hauv dej).

Child los ntawm 20-40 kg lub cev hnyav muab 500-1000 mg ib hnub ob zaug (los yog ib nrab ntawm ib tug tag nrho cov ntsiav tshuaj yaj nyob rau hauv dej).

Cov me nyuam uas ntau tshaj 40 kg yog muab 1000 mg (i.e., ib ntsiav tshuaj) ib hnub ob zaug.

Yuav ua li cas npaum li cas koj yuav tsum tau noj cov tshuaj "Vilprafen" (1000 mg) Lub caij ntawm kev kho mob nrog rau qhov no cuab tam yog tsuas txiav txim los ntawm tus kws kho mob (feem ntau yog 5-21 hnub, nyob ntawm seb lub heev thiab qhov xwm ntawm tus kab mob).

Scheme Helicobacter txoj kev kho (kev kho mob ntawm pais plab ulcers)

Tam sim no uas koj paub yuav ua li cas coj "Vilprafen Soljutab 1000". Yog hais tias koj xav tau txoj kev kho ntawm H. pylori, cov tshuaj no yog muab nyob rau hauv ib tug ntim ntawm 1 g ib hnub ob zaug rau 1-2 lub lis piam. Nyob rau hauv kev npaj no yuav tsum tau ua ke nrog rau lwm cov tshuaj mas siv nyob rau hauv lawv cov txuj koob tshuaj ( "Famotidine" "Omeprazole" "omez" "omez D" thiab thiaj on.).

Dispersible tshuaj yuav tsum noj lus nyob rau hauv ntau txoj kev. Ntsiav tshuaj yog nqos tag nrho (cov dej) los yog pre-yaj nyob rau hauv 20 ml ntawm cov dej. Nyob rau hauv lub caij nyoog kawg no cov ntaub ntawv, ua ntej lub txais tos nws yog tsim nyog los sib tov meej lub resulting ncua kev kawm ntawv.

Sab los tom qab siv cov tshuaj

Analogs "Vilprafen 1000" thiab qhia tshuaj nws tus kheej tej zaum yuav ua rau ib tug xov tooj ntawm undesirable tshua. Ntawm cov kev phiv ntau cai no muaj raws li nram no:

• Hnyuv: plab tsis xis nyob, mob plab tsis xis nyob, xeev siab, raws plab, stomatitis, ntuav, quav tawv, pseudomembranous mob plab, thiab tsis qab los noj mov.
• Kev ua xua: urticaria, anaphylactoid tshua, erythema multiforme, angioedema, bullous dermatitis, Stevens-Johnson syndrome).
• Zhelchevyvodyashie txoj kev thiab lub siab daj ntseg, hepatic kawg.
• Tsis totaub: nraum koob-hais txog tsis hnov lus zoo.
• Lwm yam: purpura.

Sis nrog rau lwm cov kev kho mob txhais tau hais tias

Txij li thaum bacteriostatic tshuaj tua kab mob tej zaum yuav txo tus antimicrobial kev txiav txim ntawm tshuaj tua kab mob bactericidal, kom tsis txhob lawv sib koom daim ntawv thov.

Josamycin yog txwv tsis pub muab ua ke nrog lincosamides. Qhov no yog vim lub fact tias nws yog tau ib tug kev sib nrig sib yuav txo tau ntawm lawv cov efficiency.

Cov neeg sawv cev ntawm macrolide ho qeeb lub tshem tawm ntawm xanthine. Qhov no yuav ua rau cov tsos mob ntawm intoxication.

Thaum siv ua ke, josamycin thiab antihistamines muaj astemizole thiab terfenadine, tej zaum yuav ua rau kom txoj kev pheej hmoo ntawm kev tsim lub neej-hem arrhythmias.

Muaj cov ntaub ntawv rau lub strengthening ntawm vasoconstriction raws li ib tug tshwm sim ntawm cov kev sib koom siv cov tshuaj tua kab mob los ntawm lub macrolide thiab ergot alkaloids.

Co-thawj coj ntawm cyclosporine thiab josamycin ua rau ib qho kev nce rau hauv cyclosporine theem nyob rau hauv cov ntshav thiab tsub kom kev pheej hmoo ntawm nephrotoxicity.

Yog hais tias concomitant siv digoxin thiab josamycin yuav ua rau kom cov theem ntawm cov thawj cov ntshav.

Tshwj xeeb cov lus qhia rau kev siv "Vilprafen 1000" tshuaj

Nyob rau hauv cov kev tshwm sim ntawm loj thiab pheej zawv plab yuav tsum tau dais nyob rau hauv lub siab qhov yuav ua rau kev tsim ib lub neej-hem pseudomembranous mob plab (nyob rau hauv cov neeg mob uas tau txais josamycin).

Nyob rau hauv cov neeg mob uas raum tsis ua hauj lwm txoj kev kho yog pom zoo noj mus rau hauv tus account lub tau ntawm laboratory kev ntsuam xyuas.

Nws yog tsim nyog los xav txog qhov yuav ua ntawm tus ntoo khaub lig-kuj mus rau ntau yam tshuaj tua kab mob cov neeg ua hauj teej tug mus rau cov pab pawg neeg ntawm macrolides (kab mob resistant rau tshuaj tua kab mob, hais txog nyob rau hauv cov tshuaj qauv, tej zaum yuav resistant rau josamycin).

Nqi thiab analogues ntawm cov tshuaj

Nqe xam tau tias yog cov tshuaj tsis yog heev. Yog li ntawd, rau 10 ntsiav tshuaj ntawm cov tshuaj koj yuav tau them txog 150 Lavxias teb sab rubles. Pom zoo, qhov no yog ib tug ncaj uas tsis muaj nqi, noj mus rau hauv tus account lub hauj lwm zoo ntawm cov tshuaj "Vilprafen 1000". Analogs cheaper koj yog tsis zoo li mus nrhiav nyob rau hauv pharmacies.

Yog hais tias koj pom tau hais tias txhob noj tshuaj, nws yuav hloov los ntawm ib tug ntawm cov nram qab no cov tshuaj: "midecamycin" "Roxithromycin", "Spiramycin", "clarithromycin", "Azithromycin" los yog "Erythromycin". Cov tshuaj no zoo sib xws rau cov neeg ntawm lub active tshuaj. Lub thiaj li hu ua yam ntxwv analogs nyob rau hauv cov tshuaj no tsis yog.

Xyuas ntawm cov neeg mob thiab cov tub txawg txog lub chaw kho mob

Niaj hnub no, muaj cov heev heev ntawm zoo tswv yim hais txog qhov no medicament. Cov neeg mob uas tau coj cov tshuaj, hais tias nws sai kho nyhuv, uas yog pom twb tom qab thawj koob. Qhov no yog tshwj xeeb tshaj yog cai nrog xws li kev txawv txav raws li tonsillitis, otitis media, sinusitis thiab cystitis.

Sab los tom qab noj cov tshuaj tshwm sim tsis tshua. Tus sau phau ntawv ntawm ib co xyuas hais txog lub siab ntawm ib lub rooj zaum, raws li zoo raws li periodic xeev siab. Los ntawm txoj kev, cov tsis kaj siab los ploj nthawv nyob rau hauv ib ob peb hnub.

Nws yuav tsum raug sau tseg hais tias ib tug loj tus naj npawb ntawm cov neeg mob txaus siab nrog rau tus nqi ntawm cov tshuaj.

Nyob rau hauv cov kev ntsuam xyuas, cov kws txawj nco ntsoov tau ntawm kev kho mob "Vilprafen" thaum lub sij hawm cev xeeb tub.