Yuav ua li cas yog Lynch syndrome? Lynch syndrome: ua, cov tsos mob, kev kho mob, kev tiv thaiv

Yuav ua li cas yog lub syndrome ntawm Lynch? Qhov no raws roj ntsha pathology, cim tias seb thaum predisposition rau tib neeg nyuv mob cancer thiab lwm yam qog nqaij hlav.

Muaj lwm yam kab mob uas ua rau kom txoj kev pheej hmoo ntawm oncological mob, txawm li cas los, analyzed lub xeev yog cov feem ntau txaus ntshai thiab feem ntau ntau. Raws li ntxhib txheeb cais, txhua txhua peb cov neeg mob tawm ntawm ib puas tus neeg mob ntawm cov nyuv mob cancer raug kev txom nyem Lynch syndrome. Lub syndrome yog kis tau los ntawm tiam mus rau tiam.

cov tsos mob

Qhov no pathology tsis manifest nws tus kheej - ib txwm tsis tuaj kawm ntawv cov tsos mob. Xav ib tug ua txhaum yuav ua tau rau cov nram qab yog vim li cas:

• nyuv mob cancer uas tsim nyob rau hauv lub kuj thaum ntxov muaj hnub nyoog (ua ntej xeeb tsib caug xyoo);
• cov ntaub ntawv rau cov xwm txheej ntawm cov nyuv mob cancer ntawm ib tug tus hluas uas muaj hnub nyoog, tseem muaj sia nyob tsev neeg keeb kwm;
• ntaub ntawv nyob rau hauv tus neeg mob ntawm uterine cancer (endometrial cancer) tsev neeg keeb kwm;
• tsev neeg zaj keeb ntaub ntawv ntawm lub zaus ntawm tus kab mob lwm yam qog nqaij hlav, correlating nrog lub saum toj no pathologies (cancer ntawm lub zes qe menyuam, mob raum, mob plab, me me hnyuv, lub siab, hws qog thiab lwm yam).

Yog hais tias koj ntshai tsam mus nrhiav tau rau ntawm Lynch syndrome, ua rau, cov tsos mob, thiab tsim nyog diagnostic ntsuas yuav tsum tau tham nrog ib tug tshwj xeeb. Nrog ib tug kws kho mob yog tias nyob rau hauv tej kev ua xyem xyav nyob rau hauv lub pathology, raws li zoo raws li yog tias koj tus txheeb ze ze thiaj paub hais tias nrog tus mob.

yog vim li cas

Lynch syndrome yog kis tau nyob rau hauv ib tug autosomal hom yam. Qhov no txhais tau tias nyob rau hauv lub xub ntiag ntawm lub mutated noob los ntawm ib tug niam txiv uas muaj ib tug hloov ntau yam ntawm 50% yuav tsum pauv mus rau txhua tus me nyuam. kab mob kis tau tus mob uas muaj feem yuav tsis nyob ntawm seb tus txiv neej pw ntawm niam txiv los yog tus me nyuam.

Yuav ua li cas tshuaj ntsuam genetic change ua rau mob cancer

Noob nqa lub Lynch syndrome, nyob rau hauv lub qub xeev yog lub luag hauj lwm rau txoj kev kho uas tsis nyob rau hauv lub caj code. Txwv tsis pub, lawv yog hu ua noob, lub luag hauj lwm rau tus kho lus ntawm unpaired bases.

Lub noob muaj cov DNA, uas hau cov lus qhia mus rau txhua txoj kev tshuaj nyob rau hauv lub cev. Raws li lub hlwb loj hlob thiab sib faib, lawv replicate lawv DNA thiab tej zaum pib me uas tsis.

Tej hlwb muaj tshwj xeeb mechanisms rau tau thiab kho kev uas tsis. Txawm li cas los, cov neeg uas tau txais pathological tej yam tshwm sim, tsis muaj lub peev xwm los kho tej kev me ntawm tes hloov. Lub tsub zuj zuj ntawm cov teeb meem ua rau kom kev tshuaj ntsuam genetic kev puas tsuaj nyob rau hauv lub hlwb, thiab nws thiaj li cov hlwb ua ua cancer.

kev kho mob

Cancer ntawm cov nyuv thiab lwm yam kabmob uas txuam nrog Lynch syndrome yog kho nyob rau hauv tib txoj kev raws li ib tug pa cancer. Feem ntau cov feem ntau txoj kev kho yuav ua tau zoo phais kom tshem tawm cov cuam tshuam hloov khoom nruab nrog. Raws li ib tug txoj cai, nws yog cov nyuv los yog zes qe menyuam thiab lub tsev me nyuam. Yog hais tias koj yog ib tug poj niam thiab koj thiaj paub hais tias nrog Lynch syndrome, cov kws kho mob tej zaum yuav muaj kom tshem tawm cov internal qhov chaw mos kabmob tam sim ntawd tom qab koj muab yug tau ib tug yam tus naj npawb ntawm cov me nyuam. Kev tiv thaiv nyob rau hauv daim ntawv ntawm cov kev phais - proven zoo qauv rau kev tiv thaiv ntawm txoj kev tuag los ntawm mob cancer.

kev tiv thaiv

Coj koj tus kheej noj qab haus huv nyob rau hauv kev tswj, coj uas tsim nyog ntsuas:

• Ua raws li cov ntsiab cai ntawm khoom noj, noj txiv hmab txiv ntoo thiab zaub. Xaiv txawv txiv hmab txiv ntoo rau hauv cov zaub mov nws yog ib txwm tag nrho. Thaum twg ua tau, xaiv whole grains.
• Ib ce muaj zog tsis tu ncua. Siv zog yuav tsum tau txais tsawg kawg nkaus peb caug feeb ntawm tw ua si - yog hais tias tsis yog txhua txhua hnub, tsawg kawg yog tsib hnub ib lub lim tiam. Yog hais tias koj tsis tau siv ib tug tshwj xeeb lub cev ua si, sib tham txog qhov no nrog koj tus kws kho mob. Pib nrog ib qho yooj yim kawm ntawv, xws li mus taug kev nyob deb li cas los yog caij tsheb kauj vab.
• Saib koj qhov ceeb thawj. Ib tug noj qab nyob zoo noj haus thiab kev qoj ib ce yuav pab kom muaj li qub ceeb thawj. Yog hais tias koj yog rog, tham nrog ib tug kws muaj txuj, muaj peev xwm mus muab lub pom poob qhov kev pab cuam. Qhov zoo tshaj plaws txoj kev - mus noj tsawg high-calorie khoom noj, thiab nyob rau tib lub sij hawm kom tus nqi ntawm lub cev ua ub no. Taw kom poob ceeb thawj ntawm ib phaus los yog kilogram ib lub lim tiam.
• Txiav kev haus luam yeeb. Kev haus luam yeeb yuav tsub kev pheej hmoo ntawm kev tsim ntau hom mob cancer thiab lwm yam kab mob. Raws li tej kev tshawb fawb, luam yeeb yuav ua rau txoj kev loj hlob ntawm cov nyuv mob cancer nyob rau hauv cov neeg mob uas Lynch syndrome.

Lo rau tej yam yooj yim cov kev cai ntawm ib tug noj qab nyob zoo txoj kev ua neej thiab koj yuav txo tau txoj kev pheej hmoo ntawm tus kab mob manifestations.