Homocysteine. Norma tshuaj nyob rau hauv cov ntshav

Homocysteine - lub npe ntawm ib tug leej faj uas muaj acid, uas tshwm sim nyob rau hauv lub cev raws li ib tug tshwm sim ntawm kev ntawm methionine. Lub peculiarity ntawm no cov ntaub ntawv uas yog hais tias nws los txog rau ib tug neeg los ntawm cov khoom noj. Methionine nyob rau hauv loj qhov ntau nyob rau hauv cov nqaij, qe thiab mis nyuj haus. Nws yog nyob rau hauv tus txheej txheem ntawm kev zom zaub mov los ntawm lub cev, yog tsim los ntawm methionine thiab homocysteine.

Cov cai ntawm no substance nyob rau hauv ib tug lossi hloov thoob plaws hauv ib tug neeg lub neej. Nrog lub hnub nyoog, cov nuj nqis yog maj nce. Ua ntej mus rau lub pib ntawm tiav nkauj tiav nraug rau cov ntxhais thiab cov tub hluas homocysteine qib tshuaj uas nws cai 5 mol / L, yog kwv yees li tib yam. Thaum tiav nkauj tiav nraug lub theem ntawm lub nce mus 7 mmol / l, thiab nyob rau hauv cov neeg hluas yog nce ntau pronounced tshaj nyob rau hauv cov ntxhais.

Yog hais tias peb tham txog cov neeg laus, cov txiv neej homocysteine, nws cai yog nyob ib ncig ntawm 10 mmol / L, ho siab tshaj rau cov poj niam. Cov laus ib tug neeg tiav niam txiv, cov siab nws theem ntawm no acid.

Cev xeeb tub poj niam homocysteine tej zaum yuav ib nyuag qis. Qhov no yog tshwj xeeb tshaj yog hnov nyob rau hauv thawj ob trimesters ntawm cev xeeb tub. Nyob rau hauv cov ntaub ntawv no, tsis txhob panic txog qhov kev kawm ntawm yam khoom uas homocysteine, npaum nws zaug tom qab 3 hnub tom qab yug tus me nyuam. Tom qab yuav txo tau ntawm lub acid theem tswj placental ncig.

Qhov no cov ntaub ntawv uas accumulating nyob rau hauv tus kab mob, khaus, them nrog epithelium, lub puab phab ntsa ntawm cov hlab ntsha, uas ua rau ncua tsim. Calcium thiab roj uas txhaws taus, precipitating lub puas nto, txhawb lub tsim ntawm sclerotic plaques. Qhov no ua rau lub fact tias cov hlab yuav sim, yuav ua tau rau thrombosis los yog kev sib tawg, yuav ua ib tug mob stroke tej zaum yuav tsim, lub ntsws embolism los yog heart attack myocardial infarction.

Cov neeg uas tau tsa homocysteine theem, chav rau cov emergence ntawm tus kab mob Alzheimer , thiab txawm lub kev loj hlob ntawm ua tem toob dementia. Thiab nyob rau hauv ua ke nrog muaj ntshav qab zib, vascular mob feem ntau tshwm sim (nephropathy, retinopathy, etc.).

Homocysteine yuav tsum tau mus xyuas tag nrho cov neeg uas muaj keeb kwm tam sim no arterial los yog venous thrombosis, ischemic plawv tus kab mob. Thiab kuj cov poj niam uas tau raug cai gynecological kab mob, thiab nws nyob ze cov txheeb ze tau raug kev txom nyem lub plawv tuaj, mob stroke los yog thrombosis.

Nws yuav pab txiav txim seb lub theem ntawm homocysteine acid tsom xam. Ntshav zauv yuav tsum tau ua nyob rau hauv ib qho kev npliag plab (tom qab ib tug noj mov yuav tsum siv tsawg kawg yog yim cov xuaj moos).

Ua qhov kev kawm ntawm no cov ntaub ntawv uas tej zaum yuav ua tau vim ob peb yog vim li cas:

• Vitaminodefitsitnoe lub xeev, tshwj xeeb tshaj yog nrog ib tug tsis muaj peev xwm ntawm cov vitamins B6, B1, thiab 12, thiab folic acid.
• Kev haus luam yeeb thiab nquag siv los ntawm kas fes (cov nuj nqis tej zaum yuav ua rau kom los ntawm 3 mmol / l).
• Sedentary txoj kev ua neej.
• Haus dej cawv.
• Cov tshuaj. Qhov no siv tshwj xeeb rau kev npaj "MTX" - folic acid antagonist (muab nyob rau hauv psoriasis), thiab lub anticonvulsant tshuaj (fetitoin - eliminates folic acid nyob rau hauv lub siab), cov pa roj nitrous oxide (siv nyob rau hauv tshuaj loog), Metformin (mob ntshav qab zib thiab polycystic zes qe menyuam syndrome) , aminophylline (siv nyob rau hauv Gynecology rau cov kev kho mob ntawm preeclampsia, suppresses cov nyhuv ntawm vitamin B6) thiab hormonal contraceptives.
• Raum insufficiency.
• Psoriasis.
• Leukemia.
• Mob ntshav qab zib mellitus.
• Congenital Hypothyroidism.
• Kab mob ntawm cov hnyuv, yuav ua tau rau malabsorption ntawm cov vitamins.

Peb niam raising homocysteine yuav ua loj teeb meem thaum lub sij hawm cev xeeb tub: intrauterine txoj kev loj hlob ruamqauj, placental abruption, thiab txawm me nyuam hauv plab tuag. Hyperhomocysteinemia - lub ntsiab zoo tshaj provoking ncuav me nyuam tau, nyob rau hauv tas li ntawd, cov me nyuam yuav yug nrog neural raj tsis xws luag thiab clubfoot. Cov tib yog vim li cas muaj peev xwm ua rau ntxiv lawm tshob rau cov poj niam, nyob rau hauv uas lub implantation ntawm lub embryo yuav tsis yooj yim sua.

Tej homocysteine cai nyob rau hauv ntau yam sclerosis.