Lozap Plus - Cov lus qhia rau Siv

Tshuaj "Lozap plus" yog nkag li zaj duab xis-coated ntsiav tshuaj, lub teeb daj los yog daj ntseg nyob rau hauv cov xim. Cov ntsiav tshuaj muaj ib tug oblong zoo thiab faib txoj kev pheej hmoo nyob rau ib sab.

qauv

Active khoom xyaw:

• hydrochlorothiazide - 12.5 mg (1 tab.);
• losartan - 50 mg (Rooj 1).

cam:

• macrogol 6000;
• microcrystalline cellulose;
• mannitol;
• krosparmelloza sodium;
• magnesium stearate;
• povidone;
• Valium;
• talc;
• zas;
• simethicone emulsion.

pharmacological los

Losartan - yog angiotensin receptor 2 antagonist uas tsis inhibit kinase 2. Kev npaj thiaj OPSS, ntshav siab, ntshav ntawm aldosterone thiab epinephrine. Ntxiv mus, cov tshuaj muaj kev vam meej diuretic nyhuv thiab thiaj li afterload.

Losartan tej zaum yuav ncua txoj kev loj hlob ntawm tej pathology li myocardial hypertrophy, raws li zoo raws li kev txhim kho cov stability ntawm tus neeg mob uas noj cov tshuaj no lub plawv tsis ua hauj lwm.

Hydrochlorothiazide belongs rau lub thiazide diuretics. Nws thiaj li reabsorption ntawm sodium thiab tsub kom cov qhov tso zis ntawm poov tshuaj, phosphate thiab hydrogen nyob rau hauv cov zis.

Nws siab tshaj plaws antihypertensive nyhuv tej zaum yuav mus txog 3 lub lis piam.

zaj lus tim khawv

• tawg nyob rau hauv ib tug neeg mob;
• txo txoj kev pheej hmoo ntawm CVD nyob rau hauv cov neeg mob uas tshaj sab laug ventricular hypertrophy thiab tawg

phiv

Sab los ntxiv rau Lozap piav nyob rau hauv cov lus qhia rau lub hauv paus ntawm lub sab los ntawm nws cov ntsiab active cov khoom xyaw - losartan thiab hydrochlorothiazide.

Kev phiv uas muaj feem xyuam rau lub hauv paus poob siab system

• kiv taub hau (tshwm sim nquag txaus).

Sab teebmeem uas ntxias fab ntawm lub cev:

• angioedema;
• laryngeal edema (thiab lwm qhov chaw ntawm lub Upper pa ib ntsuj av tau);
• ua xua;
• vasculitis;
• Henoch tus kab mob.

Kev phiv uas muaj feem xyuam rau lub plawv (plawv system):

• tawg.

Kev phiv uas muaj feem xyuam rau cov hnyuv (kev pheej hmoo ntawm tsawg tshaj li 1%):

• kab mob siab;
• raws plab;
• kom nyob rau hauv daim siab transaminases.

Kev phiv uas muaj feem xyuam rau cov pa system:

• hnoos.

Kev phiv uas muaj feem xyuam rau cov dej-ntsha tshuav (kev pheej hmoo ntawm tsawg tshaj li 1%):

• hyperkalemia.

Contraindications

• tawg;
• anuria;
• hypovolemia;
• kawg ntawm lub raum thiab lub siab;
• muaj hnub nyoog ntawm 18 xyoo;
• rhiab heev rau lub Cheebtsam;
• cev xeeb tub;
• lactation.

Yog hais tias tus neeg mob lub cev xeeb tub tshwm sim tiv thaiv ib tug tom qab ntawm cov tshuaj noj, nws yuav tsum tam sim ntawd yuav muab tso tseg. Qhov tseeb hais tias Lozap ntxiv ncaj qha kev cuam tshuam rau lub renin-angiotensin system, uas yuav ua tau kom me nyuam hauv plab tuag nyob rau hauv lub xeem ob trimesters ntawm cev xeeb tub.

Ntsiav tshuaj "Lozap plus" mus coj ib tug cev xeeb tub tus neeg mob tseem ua tsis tau pom zoo vim hais tias cov tshuaj yuav ua rau mob daj ntseg nyob rau hauv tus me nyuam mos, thiab thrombocytopenia nyob rau hauv leej niam. Therapy ua siv diuretics, nyob rau hauv cov ntaub ntawv no tsis pab kom tsis txhob muaj toxicity.

overdose

Cov tsos mob ntawm overdose:

• txos cov ntshav siab;
• bradycardia;
• tachycardia;
• lub cev qhuav dej (vim muaj zog zis tso zis).

overdose tshuaj kho mob yuav tsum tau pib nrog pais plab lavage nyob rau hauv cov kev tshwm sim hais tias tus neeg mob tau noj Lozap ntxiv tsis ntev los no. Ces tus neeg mob yog tsim nyog symptomatic kev kho mob, thiab nyob rau hauv lwm tus neeg mob - tus kho lus dej thiab mob electrolyte teeb. Hemodialysis yuav tsis tau tshem tawm raws li losartan thiab nws cov metabolites.

tshuaj cov kev sib tshuam

Losap ntxiv potentiates qhov kev txiav txim ntawm lwm yam antihypertensive tshuaj nyob rau hauv cov ntaub ntawv ntawm lawv cov neej coj siv. Cov tshuaj kuj ua rau ib tug potentiation ntawm orthostatic hypotension, nyob rau hauv rooj plaub thaum ua ntawv thov ua ke nrog barbiturates.