"TSifran ST": analogues, cov lus qhia rau kev siv thiab tus nqi

"TSifran ST" - thaum lawv tseem tshuaj nrog active tshuaj tinidazole thiab ciprofloxacin. Nws yog npaj rau cov kev kho mob ntawm kis kab mob ntawm tus mob huam thiab mixed kab mob, txoj kev loj hlob ntawm cov uas pab aerobes thiab anaerobes.

Nws nqa tawm zus tau tej cov ntau hom ntawm kev npaj "TSifran". tso tawm hauv daim ntawv ntawm cov tshuaj - coated ntsiav tshuaj, qhov muag dauv, tov rau Txoj kev lis ntshav.

Tinidazole yog tsim ntawm imidazole. Cov khoom muaj antibacterial thiab antiprotozoal kev ua si, siv nyob rau hauv cov kab mob tshwm sim los ntawm anaerobes.

Ciprofloxacin belongs rau lub tshuaj tua kab mob, rendering ib tug ntau ntawm cov kev ua ub no. Yuav kom nws raug aerobic (feem ntau ntawm cov aerobic, uas yog gram-zoo, gram-tsis zoo).

Ib yam li cov thawj, thiab analogues "TSifran ST", zoo tiv nrog kev pab raws qib.

pharmacodynamics

Tinidazole uas muaj feem xyuam rau anaerobes, yog siv los kho cov cov ntsws kabmob nyob rau hauv lub qhov ncauj kab noj hniav, nyob rau hauv lub peritoneum thiab pelvic.

Txij li thaum co kab mob feem ntau yog tov (tsim nyob rau hauv tus ntawm aerobic thiab co), raws li ib feem ntawm cov tshuaj yog tam sim no ciprofloxacin tshuaj tua kab mob, ib tug depressing ntxim rau cov kab mob teej tug mus rau lub aerobes.

tshuaj

Basic tshuaj muaj thawj siv yeeb tshuaj thiab analogues "TSifran ST", yog zoo yaim nyob rau hauv lub mob huam thiab muab faib rau ntaub so ntswg, lub cev. Lawv siab tshaj plaws concentration cai nyob rau hauv lub cev tom qab ib qho nruab nrab ntawm 1.5 lub sij hawm tom qab lub allergic ntawm cov tshuaj mus rau hauv txoj hnyuv ib ntsuj av.

Tinidazole muaj ib tug bioavailability ntawm 100%, yog cov tso tawm rau 10-12 teev. Kev sib txuas lus nrog cov ntshav cov nqaijrog yog negligible - 12%. Ekskretirovanie tshwm sim nyob rau hauv cov kua tsib, tinidazole txog 25% tas nyob hauv cov zis unchanged. Metabolites yog tshem tawm nyob rau hauv tib yam. Ib tug me ib feem ntawm cov tivthaiv nyob ntawm lub cev nyob rau hauv cov quav.

Ciprofloxacin nrog bioavailability ntawm kwv yees li 70% ntawm cov feem ntau zoo-absorbed thaum nrog siv. Tob tob mus rau hauv lub cev nrog rau khoom noj khoom haus, muaj kev tivthaiv uas muaj nyob rau hauv nws cov qauv "TSifran ST" (analogue ntawm lub lub tebchaw) yog absorbed ntau maj mam. Ciprofloxacin uake rau ntshav ntawm 20-40%. Ib nrab metabolism tshwm sim nyob rau hauv lub siab, ib nrab ntawm cov tshuaj nkag mus rau hauv cov zis zoo nkaus li unchanged. Hais txog 15% ntawm ciprofloxacin yuav siv sij hawm rau hauv daim ntawv ntawm metabolites thiab tso tawm nyob rau hauv ib daim ntawv 15-30% ntawm cov quav raug muab tshem tawm, lub tshuav ib feem - nrog bile. Rau ib nrab kev tshem tawm yuav siv sij hawm ib tug nruab nrab ntawm 4 teev, tab sis lub sij hawm no yuav ua tau ntev dua nyob rau hauv cov neeg laus cov neeg mob, thiab yog hais tias tus neeg mob qhia nyob rau hauv lub raum mob.

Indications "TSifran ST" tshuaj

Xav txog cov neeg nyob rau hauv uas tso cai rau kev siv ntawm cov nyiaj "TSifran" phau ntawv qhia. Nqe thiab analogues ntawm cov tshuaj txiav txim cov hauj lwm zoo ntawm cov kev kho mob ntawm cov nram qab no cov kab mob:

• mixed kab mob, txoj kev loj hlob ntawm uas tshwm sim nyob rau hauv tus ntawm cov kab mob (aerobic thiab co);
• raws plab thiab dysentery ntawm ntau yam etiologies (amoebic mixed (kab mob thiab amoebic)).

Cov tshuaj haum rau cov kev kho mob ntawm mixed kab mob:

• kab dab tshwm sim nyob rau hauv lub qhov ncauj kab noj hniav kabmob (.. nyob rau hauv t h periostitis, periodontitis);
• txaj tawm;
• trophic ulcers, ntshav qab zib ko taw syndrome;
• kab dab rau nqaij mos, daim tawv nqaij;
• nyob rau hauv mob osteomyelitis;
• kab mob uas ua los ntawm cov lag luam thiab sawv nyob rau hauv qhov kev txiav txim ntawm cov kab mob (aerobes, anaerobes);
• gynecological kab mob inflammatory xwm;
• kab mob nyob rau hauv lub peritoneum;
• empyema;
• mob ntsws rwj;
• sinusitis, uas dhau nyob rau hauv lub mob daim ntawv.

Contraindications

"TSifran" yuav tsum noj nyob rau hauv tag nrho cov mob. Xyuas analogs pub rau xaiv tsim nyog kho.

Cov lus qhia txwv tsis pub siv cov tshuaj nyob rau hauv lub xub ntiag ntawm ib co ntawm cov teeb meem:

• organic Cns kab mob;
• Leaky mob porphyria;
• Hloov hlwb pob txha pathology (lus hematopoiesis txheej txheem);
• cov kab mob ntawm cov ntshav (nyob rau hauv keeb kwm).

Contraindications kuj npau taws me ntsis rau Cheebtsam ntawm cov tshuaj, nyuam, mis-pub mis. Cov tshuaj tsis yog muab rau cov neeg mob uas yau dua 18 xyoo. Cov lus qhia "TSifran ST" tsis tso cai rau cov kev siv cov dej cawv.

Cov tshuaj nyob rau hauv cov neeg laus muaj ib co nta tshwj xeeb, yog li yuav paub tseeb tias nws yog tsim nyog los ua raws li cov tswv yim pom zoo ntawm cov kws kho mob. Ceev faj yog yuav tsum tau thaum:

• kev ua txhaum qhia nyob rau hauv daim siab thiab lub raum;
• convulsive lub xeev (keeb kwm);
• qaug dab peg;
• kev puas hlwb;
• cov neeg pluag ncig nyob rau hauv lub hlwb;
• vascular atherosclerosis, nyob rau hauv lub hlwb.

Siv cov tshuaj, tshuaj

"TSifran ST", ib tug analog ntawm cov tshuaj yog cov sib txawv txoj kev ntawm daim ntawv thov thiab siv nyob rau hauv txawv koob tshuaj. Tus thawj formulation npaj rau hauv kev siv, noj tom qab noj mov (2 lub sij hawm txhua txhua hnub). "TSifran ST" ntxuav cia nrog dej kom ntau. Nws yog txwv tsis pub ua txhaum lub meej mom ntawm cov ntsiav tshuaj, koj yuav tsum tau haus nws nyob rau hauv nws txoj kev paub.

Cov pom zoo koob tshuaj rau cov neeg laus yog:

• ntsiav tshuaj, uas muaj xws li cov neeg ntawm ciprofloxacin thiab tinidazole tam sim no ntawm 250 thiab 300 mg, feem - 2 pieces;
• ntsiav tshuaj uas muaj ciprofloxacin thiab Tinidazole 500 mg thiab 600 - 1 pcs.

Rau cov tshuaj pleev siv cov tshuaj rau kub lug ob lub qhov muag yuav tsum tau ib tug los yog ob tug ncos txhais tau tias. Kev kho mob yuav tsum tau nqa tawm nrog ib tug caij nyoog ntawm 1-4 lub sij hawm. Yog hais tias tus mob pab, koj yuav ua rau kom lub luv.

Sab los "TSifran ST" tshuaj

"TSifran ST" (analogue ntawm yooj yim tshuaj) tej zaum yuav ntxias ib co undesirable tshua.

Digestive system:

• gepatonekroz;
• kab mob siab;
• cholestatic daj ntseg (lub siab tshaj plaws uas yuav muaj ntawm nws txoj kev loj hlob nyob rau hauv cov neeg mob uas mob siab);
• raws plab, flatulence, mob plab;
• xeev siab thiab ntuav;
• unpleasant saj nyob rau hauv lub qhov ncauj hlau;
• cov neeg pluag qab los noj mov;
• dryness ntawm txheej hauv ob sab phlu ntawm lub qhov ncauj kab noj hniav.

Lub paj hlwb:

• thrombosis rau cerebral leeg;
• tsaus muag;
• High ICP;
• migraine;
• kiv taub hau, mob taub hau;
• psychotic tshua;
• tawm hws;
• tsis muaj cov pw tsaug zog;
• co;
• tsis muaj zog, qaug zog;
• convulsions;
• peripheral neuropathy;
• dysarthria;
• teeb meem nrog kev sib koom tes ntawm taw.

Sau ntawv thiab lwm yam undesirable los "TSifran ST" kev qhia ntawv. Nqe nyob rau hauv pharmacies analogues txiav txim tsis tau tsuas yog cov miv nyuas siv zug ntawm cov tshuaj, tab sis kuj muaj cov ib co mob tshwm sim.

tsis totaub:

• qhov muag plooj tsis pom kev;
• hloov nyob rau hauv kev txiav txim zoo ntawm tsis hnov tsw;
• dysgeusia;
• cov neeg pluag lub rooj sib hais.

Plawv system:

• tsis tshua muaj ntshav siab;
• kev hloov nyob rau hauv cov atherosclerosis ntawm lub siab los;
• tachycardia.

Mob txeeb system :

• interstitial nephritis;
• teeb meem nrog feem ntawm cov zis;
• tsim ntawm ntau cov nqi ntawm cov zis;
• raum glomerular lesion;
• zis nyob rau ntawd tsim ntsev muaju;
• Ntshav txiav txim nyob rau hauv cov zis muaj pes tsawg leeg.

Tau cov tsos mob ntawm kev ua xua thiab lwm yam phiv los, cov kev hloov nyob rau hauv laboratory tsis, ntau yam teeb nyob rau hauv lub hematopoietic system.

tshuaj cov kev sib tshuam

"TSifran ST" (analogue ntawm lub active tivthaiv) yuav tsum tsis txhob ua ke nrog "ethionamide". Cov tshuaj ua ke nrog tej yam tshuaj tua kab mob thiab sulfonamides.

Thaum siv nrog cov "pentobarbital" pom tus acceleration ntawm metabolism. Cov tshuaj yuav pab kev txiav txim ntawm ethanol thiab anticoagulants.

ceev faj

Thaum lub sij hawm txoj kev kho xav tau raws li me ntsis li sai tau mus nyob twj ywm nyob rau hauv tus ntawm tshav ntuj. Nws yog txwv tsis pub mus koom ua ub no uas nyob rau hauv cov kev kho mob ntawm cov tshuaj tej zaum yuav phomsij lub noj qab haus huv (kev saib xyuas xav tau kev pab, sai manifestation ntawm lub cev muaj zog thiab kev puas hlwb tshua). Thaum lub sij hawm txoj kev kho, xyuas ntawm peripheral cov ntshav.

Analogs, xyuas, nqi

Thaum muab "TSifran ST" analogues, nqe tseem ceeb rau cov neeg mob. Cov feem ntau siv tshuaj. Nqi ntsiav tshuaj nrog ib tug cov ntsiab lus uas yooj yim tshuaj 250 thiab 300 yog kwv yees li 36-460 mg rubles nqi ntsiav tshuaj qhov twg muaj ib 500 thiab 600 mg loj Cheebtsam - txog 79-500 rubles.

Yuav ua li cas yuav hloov tau "TSifran ST"? Lavxias teb sab analogs yog cheaper. Tus thawj cov tshuaj yuav tsum tau hloov, piv txwv li, "Ciprofloxacin" (10-25 rubles). Indian counterparts, koj muaj peev xwm xaiv "Tanidazol Ciprofloxacin +" los yog "Tsiprolet A" (150-325 rubles). Nws yog ib cov tshuaj no mas hloov los ntawm "TSifran ST".

Judging los ntawm cov kev txheeb xyuas, tus thawj tshuaj copes zoo nrog tus mob khaub thuas, tshwj xeeb tshaj yog yog hais tias tus kab mob pib. Thaum siv nyob rau hauv thaum ntxov hnub ntawm lub cev ntas, nws tso cai rau koj mus kho ntau yam poj niam o. "TSifran ST" mus sai sai pab txhawb rau tus neeg mob tus mob.

Yeej tshuaj tua kab mob siv tom qab ua hauj lwm thiab nyob rau hauv tus neeg mob qhov twg cov khiav nyob rau hauv lub cev mob hnyav o, uas rau ib ntev lub sij hawm tsis ploj, vim muaj ntau li ntau tshwm sim. Cov neeg xyuas taw tes tias lub analogues yog tsis zoo li thiab zoo taus.

Tshuaj "TSifran ST" coj tsuas yog tom qab qhov kev xeem thiab tus kws kho mob li tau teem tseg. Nws yog tsis tsim nyog rau nws tus kheej-medicate, vim hais tias lub txim yuav ua tau teeb meem loj.