Cov tshuaj "famotidine": xyuas ntawm cov kws kho mob nyob rau kev siv ntawm

Pais plab hyperacidity txhawb tsis tau tsuas yog cov tsos ntawm tsis kaj siab ncus, tab sis txoj kev loj hlob ntawm loj cov kab mob, xws li yaig thiab mucosal ulcers. Yog li ntawd, nyob rau lub thawj kos npe rau ntawm tej sib txawv yuav tsum tam sim ntawd sab laj ib tug kws kho mob, ib tug gastroenterologist.

Cov kev pab ua niaj hnub no muaj ntau ntau cov tshuaj uas inhibit acid secretion ntsev. Cov feem ntau pheej yig thiab siv tau txhais tau tias muaj xws li tshuaj "famotidine". Xyuas ntawm cov kws kho mob hais tias cov tshuaj yuav tsum tau muab nthuav hauv qab no.

tso tawm daim ntawv no, ntim, kev piav qhia thiab muaj pes tsawg leeg

Kev npaj "ntawm famotidine" yog muab nyob rau hauv daim ntawv ntawm cov me me pellets. Lawv yog cov yeej thiab lenticular zoo, thiab daim tawv nqaij daj los yog xim av.

Lub active ingredient ntawm no neeg uas sawv cev famotidine. Dhau li nws, cov khoom muaj koom haum pab Cheebtsam li magnesium stearate, pob kws starch, microcrystalline cellulose, pob zeb ntais dioxide, talc, thiab sodium croscarmellose.

Nrog kev hwm rau lub plhaub, nws muaj hypromellose, talc, Macrogol 6000, titanium dioxide (E171) thiab xim av hlau oxide xim.

Tshuaj "famotidine" Diam duab uas yog nyob rau hauv no tsab xov xwm no yog muaj nyob rau hauv sawv hlwv packs, uas yog muaj nyob rau hauv daim ntawv cartons.

Pharmacology ntawm anti-rwj tshuaj

Yuav ua li cas yog zoo tshaj plaws tshuaj "famotidine"? Xyuas tau qhia hais tias nws yog ib tug sib tw antagonist ntawm histamine. Sej lub histamine H2-receptors ntawm lub parietal hlwb, nws thiaj li muaj qhov tso pa tawm ntawm hydrochloric acid, ntxias los ntawm ntau yam stimuli. Nws kuj txo cov basal ntau lawm. Thaum zoo li no tshwm sim rau ib tus twg lesser secretion inhibition tshwm sim los pepsinogen.

Txais ntawm cov tshuaj nyob rau hauv kev saib xyuas tsis hloov ntau ntau ntawm gastrin nyob rau hauv cov ntshav. Lub caij ntawm qhov kev txiav txim raws li qhov ib daim ntawv thov koob-dependent thiab yog 12-25 teev.

Lub kinetics ntawm yeeb tshuaj

Nyob qhov twg lub haum ntawm cov tshuaj "famotidine"? Xyuas hais tias tom qab qhov ncauj thawj coj ntawm cov tshuaj yog sai absorbed los ntawm cov hnyuv ib ntsuj av. Ntxiv mus, nws ncov concentration yog tiav nyob rau hauv cov ntshav rau 1-3 teev.

Kev sib txuas lus ntshav protein yog 17-20%. Ib tug tshuaj yog tas nyob rau hauv niam cov kua mis thiab penetrates los ntawm lub placental barrier.

Kwv yees li 30-37% ntawm cov famotidine yog metabolized nyob rau hauv lub siab. Nws tso zis yog tas los ntawm ob lub raum.

zaj lus tim khawv

Yuav ua li cas qhia tau hais tias cov tshuaj "famotidine"? Kev siv cov no neeg sawv cev muaj ib tug zoo ntxim nyob rau lub xeev ntawm cov hnyuv nyob rau hauv:

• erosive gastroduodenitis;
• rwj thiab kev tiv thaiv ntawm nws cov tsis tshua mob heev;
• haumxeeb dyspepsia ;
• symptomatic thiab kev nyuaj siab rwj;
• reflux esophagitis;
• ntau endocrine adenomatosis;
• Zollinger-Ellison syndrome;
• mauj mastocytosis;
• kev tiv thaiv ntawm relapse ntawm los ntshav nyob rau hauv lub postoperative lub sij hawm;
• Kev tiv thaiv ntawm aspiration ntawm pais plab kua txiv nyob rau hauv cov neeg niaj phais nyob rau hauv kev tshuaj loog (nrog Mendelson tus syndrome) ;
• kev tiv thaiv ntawm aspiration pneumonitis;
• nrog retrosternal dyspepsia los yog epigastric mob uas tshwm sim nyob rau hmo ntuj los yog tom qab ib tug noj mov.

Contraindications kom tau txais kev tiv thaiv-rwj ntsiav tshuaj

Thaum koj yuav tsum tsis txhob siv cov ntsiav tshuaj "famotidine"? Xyuas lub xeev uas lub contraindications ntawm cov tshuaj no yog cov nram qab no hais tias:

• kev pub niam mis;
• cev xeeb tub;
• hnub nyoog peb xyoos thiab ib lub cev muaj ceeb thawj mus rau 20 kg;
• npau taws me ntsis rau famotidine thiab lwm yam blockers ntawm histamine H2-receptors.

Nrog huab ceev faj yog ib yam tshuaj kws kho rau tiv thaiv, daim siab los yog raum tsis ua hauj lwm nyob rau hauv cov me nyuam thiab mob npuas paug ntawm lub siab encephalopathy (portosystemic).

Yuav ua li cas kuv yuav tsum tau coj "famotidine" ntsiav tshuaj?

Xyuas tau qhia tias cov tshuaj yog coj hais lus, tsis muaj kev zom khoom.

Cov neeg laus nrog ulcers ntawm lub digestive ib ntsuj av tau thiab erosive gastroduodenitis taw 20 mg ib hnub ob zaug. Yog hais tias qhov kev kawm, txhua hnub ntau npaum yuav muab ntau zog rau 80 los sis 160 mg. Qhov no txoj kev kho yuav tsum kav tsawg kawg yog 4-8 lub lis piam.

Nyob rau hauv lub xub ntiag ntawm dyspepsia, yog txuam nrog ntau zog secretion ntawm lub plab, cov neeg mob yuav muab 20 mg ntawm yeeb tshuaj ib zaug ib hnub twg.

Rau kev tiv thaiv ntawm lub rwj rov siv yeeb tshuaj 20 mg txhua hnub thaum yuav mus pw.

Thaum Zollinger-Ellison syndrome ntau npaum ntawm cov tshuaj thiab ntev ntawm txoj kev kho kev kawm no teem ib lub zuj zus. Cov thawj zaug koob tshuaj medicament thaum xws mob yog feem ntau 20 mg. Nws yog coj txhua 6 teev. Yog hais tias tsim nyog, nws yuav muab ntau zog rau 160 mg.

Thaum refpyuks esophagitis siv yeeb tshuaj los ntawm 20-40 mg ib hnub ob zaug rau - kaum ob lub lis piam.

Cov me nyuam muaj peb xyoos ntawm lub rwj thiab reflux esophagitis tshuaj ntawm tus nqi ntawm 2 mg / kg ib hnub twg.

phiv

Yuav ua li cas tshwm sim tsis zoo yog xam qhovkev nyob rau hauv cov tshuaj "famotidine"? Xyuas ntawm cov kws kho mob qhia cov nram qab no cov tshuaj tiv thaiv:

• qhov ncauj qhuav, qaug zog, ntuav, kiv taub hau, mob plab, nkees nkees, cem quav, disturbance ntawm qab los noj mov, nervousness, nce ua si ntawm lub siab enzymes, daim tawv nqaij ua pob liab vog, mob pancreatitis;
• tsis meej pem, bradycardia, hallucinations, vasculitis, pyrexia;
• arrhythmia, qhuav tawv nqaij, txo cov ntshav siab, AV-thaiv;
• alopecia, leukopenia, pob txuv vulgaris, qhov muag plooj tsis pom kev, antionevrotichesky o, khaus, agranulocytosis, bronchospasm;
• mob taub hau, xeev siab, insomnia, ntxhov siab vim, tsam plab, tinnitus, raws plab, kev nyuaj siab, kab mob siab, psychosis, paresis ntawm kev pab;
• anaphylactic poob siab, hypoplasia, ces meem kev txhawj xeeb;
• thrombocytopenia, amenorrhea, pancytopenia, hyperprolactinemia, aplasia ntawm lub hlwb pob txha;
• gynecomastia, impotence, kub taub hau, mob nyob rau hauv cov pob qij txha;
• tsis libido, leeg mob, nce nyob rau hauv urea theem nyob rau hauv cov ntshav.

Xyuas

Kws txawj hais tias cov tshuaj "famotidine" no tsis yog tus zoo tshaj plaws los tiv thaiv-rwj neeg sawv cev. Dua li no, nws yog heev feem ntau siv nyob rau hauv cov kev kho mob ntawm txoj hnyuv kab mob.

Raws li rau cov neeg mob, lawv cam hais tias nyob rau hauv thaum ntxov hnub ntawm kev kho mob cov tshuaj behaves zoo heev. Tom qab, nws yog haujlwm.